Bot:
Also scarlet fever

Why Leptospirosis is a bitch?

Pathophysiology

Phase II (immune phase)

• CNS-dominant anicteric
• Respiratory-dominant anicteric
• Hepatic, or icteric (Weil's disease)

Diagnosis

Treatment

+ وياها fever بس نسيت اذكرها

I also forgot to mention: Leptospirosis can also cause petechial rash, purpura, and epistaxis.

This is due to endothelial dysfunction & resultant thrombocytopenia

وهاي كيسات عن الليبتو:

A 47-year-old health-care worker presents to the ER with 2 days of fever and dry cough. He returned home from a 2-week trip to Puerto Rico 6 days ago. In Puerto Rico, he volunteered to assist in recovery efforts following Hurricane Irma. He reports fever and myalgias a few days before returning home. He states that he felt fine for the last 3 days, but woke up this morning with fever and cough. He also noticed that he was jaundiced and had developed a petechial rash on his lower extremities. On physical examination, his vital signs show a temperature of 39 °C, heart rate of 123 beats per minute, respiratory rate of 20 breaths per minute, and blood pressure of 100/70. He is icteric, has an enlarged liver 3 cm below the right costal margin, and a fi ne petechial rash on both lower extremities. You suspect leptospirosis and have just ordered the appropriate diagnostic tests including a microscopic agglutination test (MAT), blood PCR test, and blood and urine cultures.
Results will not be available for several days. Of the following options, the best next steps in managing the patient include:


(a) Hospitalization, await definitive test results, provide aggressive supportive care
(b) Hospitalization, begin empiric intravenous benzylpenicillin, provide aggressive supportive care
(c) Request a chest radiograph, complete blood count, comprehensive metabolic panel, and coagulation studies, and advise the patient to return to the office the next day to review the test results
(d) Hospitalization, begin empiric oral amoxicillin, provide aggressive supportive care