ACEi + ARBs have anti-proteinuria effect in addition to their anti-hypertensive effect
عود فرحان خلصت من الهستو
رجعلي بالباثو وهسة بالنفرولوجي لكيته كدامي:
رجعلي بالباثو وهسة بالنفرولوجي لكيته كدامي:
Lab Rats In Lab Coats
عود فرحان خلصت من الهستو رجعلي بالباثو وهسة بالنفرولوجي لكيته كدامي:
Normal glomerulus
(Green arrows point to glomerular capillaries)
(Green arrows point to glomerular capillaries)
Lab Rats In Lab Coats
Focal Segmental GlomeruloSclerosis (FSGS)
FSGS
Blue arrow: segmental sclerosis
Yellow arrow: normal glomerulus
Blue arrow: segmental sclerosis
Yellow arrow: normal glomerulus
Wegener's granulomatosis
Is an autoimmune disorder that results in inflammatory reactions, necrotizing vasculitis and granulomatous lesions in various tissues and organs of the body.
Is an autoimmune disorder that results in inflammatory reactions, necrotizing vasculitis and granulomatous lesions in various tissues and organs of the body.
What parts of the body are affected by Wegener's?
Almost any part of the body can be affected. However, three sites are most typically involved: these are the upper airways - such as the ears, nose and sinuses; the lungs; and the kidneys.
In the case of the ears and
sinuses, the patient may complain of pain in these areas، deafness may also develop, bleeding from the nose (epistaxis) is also a very common event, lung involvement may be noticed by the haemoptysis and kidney inflammation by haematuria.
Almost any part of the body can be affected. However, three sites are most typically involved: these are the upper airways - such as the ears, nose and sinuses; the lungs; and the kidneys.
In the case of the ears and
sinuses, the patient may complain of pain in these areas، deafness may also develop, bleeding from the nose (epistaxis) is also a very common event, lung involvement may be noticed by the haemoptysis and kidney inflammation by haematuria.
There are several other commonly affected sites, These include the skin in which typical rash or even ulcers may be present, Joint inflammation, Fingertips inflammation and tongue ulcers.
In addition to ESR, CRP, CBC and taking biopsy is there any specific blood test to make the dx?
Yes, a big breakthrough in diagnosing Wegener's was described in the 1980s, when it was found that a particular blood test was very useful in identifying patients with Wegener's.
This is called :ANCA (antineutrophil cytoplasmic antibodies) test.
This test is very accurate and can tell us very precisely what’s the diagnosis.
Yes, a big breakthrough in diagnosing Wegener's was described in the 1980s, when it was found that a particular blood test was very useful in identifying patients with Wegener's.
This is called :ANCA (antineutrophil cytoplasmic antibodies) test.
This test is very accurate and can tell us very precisely what’s the diagnosis.