They are the most common type of renal cysts. The incidence increases with age. Approximately 25% of people who are 40 years or older and approximately 50% of people 50 years and older have simple kidney cysts.

They are mostly asymptomatic and detected incidentally upon radiological exams of the abdomen or at autopsy. And they can be bilateral. Management is not required unless the cyst becomes infected or enlarges and causes symptoms.

If a cyst becomes infected, antibiotics are necessary. If a cyst is so large that it is exerting mass effect or pressure on another organ, the two most common procedures for treating simple kidney cysts are (1) aspiration and sclerotherapy and (2) laparoscopic surgery to remove the cyst. Ethanol is most commonly used in sclerotherapy.

Signs and symptoms of cystic renal cell carcinoma include:

- Macroscopic hematuria (in 60% of patients)
- Flank pain (40%)
- Palpable flank mass (30-40%)

But only 10-15% of patients will present with the classic triad of symptoms.

Notes on Hematuria:

Red urine is not always caused by hematuria. A variety of medications, food dyes, and metabolites can cause heme-negative red urine, or pigmenturia. Furthermore, not all dipstick tests positive for blood are due to hematuria. In addition to detecting heme in intact red blood cells (RBCs), urine dipsticks detect free hemoglobin (commonly associated with hemolytic anemia) and myoglobin (commonly associated with rhabdomyolysis), hence leading to false-positive tests for hematuria.

Whenever the urine dipstick is positive for blood, and the microscopic exam of the urine does not show RBCs, myoglobinuria and hemoglobinuria should be considered.

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Bot:

من ضمنهم الشوندر (beets) ممكن يسبب ادرار لونه وردي مائل للحمر لأن بيه محتوى عالي من الصبغات واكو بعض الادوية تناولها هم يسبب discoloration of urine but I forgot the names
فالمحللين الي يشتغلون بالمختبرات.. questioner is important for the patient when we do these tests (especially the urine test) before we can give any conclusion by ourselves

يب صحيح
أدوية مثل ال phenazopyridine (مسكن آلام يستخدموه لآلام الجهاز البولي بالتحديد)، وال rifampin ويمكن حتى الفلاجيل (metronidazole)

Wilms tumor, or nephroblastoma:
is the most common renal cancer in the pediatric age group. It is also the most common pediatric abdominal cancer and the fourth most common pediatric cancer overall. 
Wilms tumor is typically found in children younger than five years old. The tumor is named after the German physician, Dr. Max Wilms, who first described it in 1899.

A 4-year-old boy was presented with right side abdominal distension and discomfort. Before that, haematuria with clots occurred intermittently and the child cried at each time of urination. That is reason the parents brought him to Children’s Hospital.

On examination:
The child’s skin looked normal,
well-nourished and apyrexial,
the abdomen was soft and not tender. At the right-side of the abdominal wall was a mass with freely movable and smooth edges. It easily palpated above and below the mass.
At the time of the clinical exam, they had to consider 4 potential diagnoses that differentiate:
(1) Wilms’ Tumor
(2) Neuroblastoma
(3) Polycystic kidney disease
(4) Rhabdomyosarcoma.

This was confirmed more by histology.

Wilms’ tumor can also run in families, although this is rare. When the child was diagnosed as Wilms’ tumors, tests can be done on parents. Screening for Wilms’ tumor is very important for children because it relates to child survival. To find kidney tumors when they are still small and have not yet spread to other organs can save their life in 4 years. Therefore, screening for Wilms’ tumor is very important for the child who has syndromes, or birth defects, or a family history.
A very simple and cheap way is for physical exams to be done by a specialist, ultrasound on a regular basis is recommended, it could be done on a 3- 4 months interval until the child reaches age of 8 years old.

+ its common metastasis is: the other kidney and lung.

Bot:

Nitrofurantoin (UT local antiseptic)
ايضا يسبب تغيير بلون الادرار جوزي مائل للاحمرار

البارحة شكد ردت اتذكره وما كدرت :")