Forwarded from 0/0 (Haidar A. Fahad)
Cysteine & Uric acid stones both cause (and are precipitated) by acidic urine.
Therefore we treat them by alkalinizing the urine with (carbonic-anhydrase inhibitors)
Therefore we treat them by alkalinizing the urine with (carbonic-anhydrase inhibitors)
Forwarded from 0/0 (Haidar A. Fahad)
0/0
Cysteine & Uric acid stones both cause (and are precipitated) by acidic urine. Therefore we treat them by alkalinizing the urine with (carbonic-anhydrase inhibitors)
أكو مركبات بالرمان (أكثر شي بقشور و—شحم—الرمان) يسموهن ellagitannins. هاي المركبات همين يعتبرن
Carbonic-anhydrase inhibitors
Carbonic-anhydrase inhibitors
Forwarded from 0/0 (Haidar A. Fahad)
أكو مركبات ثانية مثل الـ Ellagic acid (والـ metabolite مالته اللي هو الـ urolithin) يُشاع أنهن يعالجن السرطان أو على الأقل يقللن من شدته ويساهمن بالحماية منه، ولهذا أكو بعض المكملات الغذائية اللي تحتوي هالمركبات بالإضافة لهواي بوستات تكول أنّ الرمان يحمي من السرطان...
باختصار: ماكو هيج شي والسالفة جذب.
باختصار: ماكو هيج شي والسالفة جذب.
As a general rule:
An alkaline pH favors the crystallization of calcium- and phosphate-containing stones, whereas and acidic urine pH promotes uric acid or cystine stones.
An alkaline pH favors the crystallization of calcium- and phosphate-containing stones, whereas and acidic urine pH promotes uric acid or cystine stones.
Forwarded from 0/0 (Haidar A. Fahad)
A 37-year-old ADPKD* female patient with positive family history was admitted in the hospital for repeated urinary tract infections for 3 years. CTU showed a complete staghorn calculus in her right kidney
Forwarded from 0/0 (Haidar A. Fahad)
0/0
A 37-year-old ADPKD* female patient with positive family history was admitted in the hospital for repeated urinary tract infections for 3 years. CTU showed a complete staghorn calculus in her right kidney
*Autosomal-Dominant Polycystic Kidney Disease (ADPKD)
Autism spectrum disorder at the molecular level:
While neurological disorders like Alzheimer's disease or Parkinson's disease have well-defined pathologies, autism and other psychiatric disorders have had a lack of defining pathology, making it difficult to develop more effective treatments.
While neurological disorders like Alzheimer's disease or Parkinson's disease have well-defined pathologies, autism and other psychiatric disorders have had a lack of defining pathology, making it difficult to develop more effective treatments.
For the new study, published in 2 November 2022, researchers examined gene expression in 11 cortical regions by sequencing RNA from each of the four main cortical lobes.They compared brain tissue samples obtained after death from 112 people with ASD against healthy brain tissue.
While each profiled cortical region showed changes, the largest drop off in gene levels were in the visual cortex and the parietal cortex, which processes information like touch, pain and temperature. The researchers said this may reflect the sensory hypersensitivity that is frequently reported in people with ASD.
Researchers found strong evidence that the genetic risk for autism is enriched in a specific neuronal module that has lower expression across the brain, indicating that RNA changes in the brain are likely the cause of ASD rather than a result of the disorder.
While each profiled cortical region showed changes, the largest drop off in gene levels were in the visual cortex and the parietal cortex, which processes information like touch, pain and temperature. The researchers said this may reflect the sensory hypersensitivity that is frequently reported in people with ASD.
Researchers found strong evidence that the genetic risk for autism is enriched in a specific neuronal module that has lower expression across the brain, indicating that RNA changes in the brain are likely the cause of ASD rather than a result of the disorder.
Source : University of California - Los Angeles Health Sciences
So the next step will be developing therapies according to these genes expression changes.
Forwarded from 0/0 (Haidar A. Fahad)
Passenger pilots are likely more susceptible to nephrolithiasis as a result of FAA* cockpit regulations, which have amplified the prevalence of a modifiable risk factor, dehydration, by causing pilots to reduce fluid intake to use the lavatory less frequently.
*FAA: Federal Aviation Administration
*FAA: Federal Aviation Administration
Forwarded from 0/0 (Haidar A. Fahad)
0/0
Passenger pilots are likely more susceptible to nephrolithiasis as a result of FAA* cockpit regulations, which have amplified the prevalence of a modifiable risk factor, dehydration, by causing pilots to reduce fluid intake to use the lavatory less frequently.…
Forwarded from 0/0 (Haidar A. Fahad)
Steinstrasse (stone street)
0/0
Steinstrasse (stone street)
Stein (stone) + Strasse (street) = Steinstrasse