Lab Rats In Lab Coats
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A lot of the appeal of internal medicine is Sherlockian—solving the case from the clues. We are detectives; we revel in the process of figuring it all out. It’s what doctors most love to do.

- Every patient tells a story
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What the patient brings to the process of diagnosis is unique: the particular and private facts of his life and illness.” And what the physician brings is the knowledge and understanding that will help him order that story so that it makes sense both to the doctor—who uses it to make a diagnosis—and to the patient—who must then incorporate that subplot into the larger story of his life.

- Every patient tells a story
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What the patient brings to the process of diagnosis is unique: the particular and private facts of his life and illness.” And what the physician brings is the knowledge and understanding that will help him order that story so that it makes sense both to the…
يأتي المريض لعملية التشخيص بشيءٍ فريد: التفاصيل الخاصة بحياته الشخصية ومرَضِه. أمّا ما يأتي به الطبيب، فهو المعرفة العلمية والقدرة الإستنتاجية التي تجعله قادرًا على ترتيب اللغز وحياكة القصة بشكلٍ يجعلها مفهومة للطبيب—الذي يستخدمها للوصول لتشخيص طبي—وللمريض—الذي يدمج قصة المرض مع القصة الأكبر التي هي حياتُه.
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From the outset, the clinician is assimilating potentially relevant information from the patient’s posture, appearance, speech, demeanour and response to questions. Who is this patient? What kind of person is he? What are his anxieties? What is the reason for consulting a doctor at this time?
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From the outset, the clinician is assimilating potentially relevant information from the patient’s posture, appearance, speech, demeanour and response to questions. Who is this patient? What kind of person is he? What are his anxieties? What is the reason…
يجمع الطبيبُ منذ بداية اللقاءِ معلوماتٍ قد تكون ذات صلة بالتشخيص مثل وقفة المريض ومظهره وطريقته بالكلام وتصرّفاته وطريقته بالإجابة. من هو هذا المريض؟ أيُّ نوعٍ من الأشخاصِ هو؟ ما هي مخاوفه والأسباب التي جعلته يزور الطبيب الآن؟
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Much information comes out of the first interaction.
The face, particularly the eyes, indicate real feelings better than words. Did your patient smile when you introduced yourself? Was it symmetrical or was there obvious facial weakness? Did he make eye contact? Was the face animated or expressionless as in Parkinson’s disease? Was the voice hoarse due to laryngeal disease, recurrent laryngeal nerve palsy or myxoedema?
Was the speech pressured, as in thyrotoxicosis or mania, or monotonous and expressionless as in severe depression? Was it slurred from cerebellar disease or a previous stroke?
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Much information comes out of the first interaction. The face, particularly the eyes, indicate real feelings better than words. Did your patient smile when you introduced yourself? Was it symmetrical or was there obvious facial weakness? Did he make eye contact?…
يمكن الحصول على الكثير من المعلومات من اللقاء الأول.
إذ يعبِّر الوجهُ، والعيونُ تحديدًا، عن المشاعر بشكل حقيقيٍ أكثر من الكلمات. هل ابتسمَ المريض عندما حيّيتَه؟ هل كانت الإبتسامة متناسقةً أم أنّ هناك ضعفًا واضحًا في أحد جانبيه؟ هل قام بأي تواصل بصري؟
هل كان الوجه طبيعيًا أم بلا تعابير كما في مرضى الشلل الرعاشي؟ هل كان الصوت غليظًا كما في أمراض الحنجرة (مثل الـ Laryngeal nerve palsy)؟ هل كان كثير الكلام ومتسرعًا كما في بعض أمراض الغدة الدرقية أو الهوس؟ أم كان رتيبًا وبلا تعابير كما في الإكتئاب الشديد؟ أو كان ثقيلًا وغير واضح كما بأمراض المخيخ والجلطات الدماغية؟
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Cortisol is a bitch
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Cortisol is a bitch
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Cushing Syndrome (CS)
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More about CS
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Cushing & Hypertension.

Also, the reason why cortisol is a bitch,
And why aldosterone is a push-over
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More about Hypertension and cortisol
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CS and hypokalemia
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CS and GFR
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A weird case of CS and nephrotic syndrome
Abdominal pain