MCQ NO 911 | pharmaceutical jurisprudence
List of drugs marked under generic name
List of drugs marked under generic name
Anonymous Quiz
18%
A. Schedule-E
21%
B. Schedule-X
55%
C. Schedule-W
6%
D. Schedule -y
MCQ NO 912 | Pharmaceutical jurisprudence
Minimum age limit for registration as pharmacist is
Minimum age limit for registration as pharmacist is
Anonymous Quiz
46%
A. 18 Years
41%
B. 21 Years
5%
C. 19 Years
7%
D. 25 Years
MCQ NO 913 | Pharmaceutical jurisprudence
Poisonous act came on ?
Poisonous act came on ?
Anonymous Quiz
59%
A. 1919
22%
B. 1948
13%
C. 1930
6%
D. 1942
MCQ NO 914 | Pharmaceutical jurisprudence
List of minimum equipments required for efficient running of pharmacy is given in schedule?
List of minimum equipments required for efficient running of pharmacy is given in schedule?
Anonymous Quiz
21%
A. Schedule-M
14%
B. Schedule-O
61%
C. Schedule-N
4%
D. Schedule-W
MCQ NO 915 | Pharmaceutical jurisprudence
Medicinal and Toilet preparation act 1955 is effectively implemented throughout India from
Medicinal and Toilet preparation act 1955 is effectively implemented throughout India from
Anonymous Quiz
31%
a) 2 nd May 1956
33%
b) 5 th June 1957
19%
c) 2 nd April 1952
17%
d) 2 nd April 1957
MCQ NO 916 | Pharmacology
Idiosyncrasy reaction of a drug is.....
Idiosyncrasy reaction of a drug is.....
Anonymous Quiz
5%
Quantitatively exaggerated response
24%
A type of hypersensitivity reaction
64%
Unpredictable, inherent, qualitatively abnormal reaction of a drug
6%
A type of drug antagonism
MCQ NO 917 | Pharmacology
A-50-year-old man has a history of frequent episodes of renal colic with high calcium renal stones. The most useful agent in the treatment of recurrent calcium stones is?
A-50-year-old man has a history of frequent episodes of renal colic with high calcium renal stones. The most useful agent in the treatment of recurrent calcium stones is?
Anonymous Quiz
23%
Acetazolamide
23%
Mannitol
30%
Furosemide
24%
Hydrochlorothiazide
MCA NO 918 | microbiology
Treponema pallidum was discovered by.....
Treponema pallidum was discovered by.....
Anonymous Quiz
11%
Burgey
26%
Louis Pasteur
36%
Landsteiner and Weiner
26%
Schaudinn and Hoffman
MCQ NO 919 | Microbiology
Peptone water medium is an example of?
Peptone water medium is an example of?
Anonymous Quiz
20%
Differential medium
45%
Semisynthetic medium
30%
Synthetic medium
5%
None of these
MCQ NO 920 | Pharmacognosy
How many isoprene unit are involved in construction of triterpenes?
How many isoprene unit are involved in construction of triterpenes?
Anonymous Quiz
29%
3
34%
4
11%
5
26%
6
🔴 Mechanism of Action 🔴
🔺Oral antidiabetic Drugs:-
🔸1. Sulfonylureas (K ATP channel blockers) & Meglitinide Or Phenilalanine analogues.
Sulfonylureas bind to Sulfonylurea receptor SUR1 on pancreatic beta cells membrane and provoke a brisk release of insulin. (Details given in below Fig.)
Meglitinide....... Also acts on SUR receptor closure to ATP sensitive potassium channels... depolarisation..... And finally insulin get released.
🔸2.Dipeptidyl peptidase4 inhibitors..... Indirectly acting secretagogues by preventing inactivation of GLP-1, GIP.
🔸3.Thiazolidinedione
Acts by enhancing the transcription of several insulin responsive genes.... Tends to reverse insulin resistance by enhancing GLUT4 expression and translocation.
🔸4. Alpha Glucosidase inhibitors.
Alpha Glucosidase is an enzyme located in brush border of small intestine & this is the final enzyme for the digestion of carbohydrates.
Inhibitors of this enzyme simply inhibit it... And there is slow down of degradation of carbohydrates and polysaccharides and Sucrose.... And less glucose get absorbed and blood glucose level get near to normal.
🔸5. Dopamine D2 agonist... Bromocriptine... Reset the insulin resistance.
🔸6.Sodium glucose co-transport-2 (SGLT-2) inhibitor.
SGLT2 transporter inhibition causes induction glucosuria and lowers blood glucose .
🔺Oral antidiabetic Drugs:-
🔸1. Sulfonylureas (K ATP channel blockers) & Meglitinide Or Phenilalanine analogues.
Sulfonylureas bind to Sulfonylurea receptor SUR1 on pancreatic beta cells membrane and provoke a brisk release of insulin. (Details given in below Fig.)
Meglitinide....... Also acts on SUR receptor closure to ATP sensitive potassium channels... depolarisation..... And finally insulin get released.
🔸2.Dipeptidyl peptidase4 inhibitors..... Indirectly acting secretagogues by preventing inactivation of GLP-1, GIP.
🔸3.Thiazolidinedione
Acts by enhancing the transcription of several insulin responsive genes.... Tends to reverse insulin resistance by enhancing GLUT4 expression and translocation.
🔸4. Alpha Glucosidase inhibitors.
Alpha Glucosidase is an enzyme located in brush border of small intestine & this is the final enzyme for the digestion of carbohydrates.
Inhibitors of this enzyme simply inhibit it... And there is slow down of degradation of carbohydrates and polysaccharides and Sucrose.... And less glucose get absorbed and blood glucose level get near to normal.
🔸5. Dopamine D2 agonist... Bromocriptine... Reset the insulin resistance.
🔸6.Sodium glucose co-transport-2 (SGLT-2) inhibitor.
SGLT2 transporter inhibition causes induction glucosuria and lowers blood glucose .
🔴ADRS OF INSULIN🔴
➡️Hypoglycemia
➡️Local reactions
➡️Allergy
➡️Edema
🔴ADRS OF SULFONYLUREAS🔴
➡️Hypoglycemia
➡️Nonspecific side effects as like nausea,vomiting, diarrhea, headache.
➡️Hypersensitivity reactionsas like rashes, Photosensitivity, flushing,and disulfiram like reactions.
➡️Hypoglycemia
➡️Local reactions
➡️Allergy
➡️Edema
🔴ADRS OF SULFONYLUREAS🔴
➡️Hypoglycemia
➡️Nonspecific side effects as like nausea,vomiting, diarrhea, headache.
➡️Hypersensitivity reactionsas like rashes, Photosensitivity, flushing,and disulfiram like reactions.
MCQ NO 921 | Pharmacology
A teratogenic action is:
A teratogenic action is:
Anonymous Quiz
8%
Toxic action on the liver
81%
Negative action on the fetus causing fetal malformation
9%
Toxic action on blood system
3%
Toxic action on kidneys
MCQ NO 922 | Pharmacology
The situation when failure due to continue administering the drug results in serious psychological and somatic disturbances is called?
The situation when failure due to continue administering the drug results in serious psychological and somatic disturbances is called?
Anonymous Quiz
8%
Sensibilization
42%
Tachyphylaxis
33%
Abstinence syndrome
16%
Idiosyncrasy
MCQ NO 923 | Pharmacology
Characteristics of ephedrine include all of the following EXCEPT:
Characteristics of ephedrine include all of the following EXCEPT:
Anonymous Quiz
16%
It is a mild CNS stimulant
26%
It decreases arterial pressure
31%
It causes tachyphylaxis with repeated administration
27%
It acts primarily through the release of stored cathecholamines
MCQ NO 924 | Microbiology
The main product of glycolysis under aerobic conditions is.....
The main product of glycolysis under aerobic conditions is.....
Anonymous Quiz
58%
Pyruvate
13%
Lactate
27%
Both
2%
None of these
MCQ NO 925 | Microbiology
The major immunoglobulin present in the human serum is?
The major immunoglobulin present in the human serum is?
Anonymous Quiz
49%
IgG
23%
IgE
9%
IgA
19%
All of these
🔴 Mechanism of Action 🔴
🔺 Glucagon :-
🔸Glucagon is hyperglycaemic principle & single chain polypeptide containing 29 Amino acids having molecular weight 3500. Secreted by alpha cells of islet of langerhans and commercially produced now by recombinant DNA technology.
🔸Glucagon binds its own receptor and couple with Gs protein activates AC and increase cAMP in liver, fat cells, heart and other tissues.
Glucagon causes hyperglycaemia by enhancing glycogenolysis and gluconeogenesis in liver.
🟢 Other hyperglycaemics..... e.g. Diazoxide, somatostatin, streptozocin.
🔺 Glucagon :-
🔸Glucagon is hyperglycaemic principle & single chain polypeptide containing 29 Amino acids having molecular weight 3500. Secreted by alpha cells of islet of langerhans and commercially produced now by recombinant DNA technology.
🔸Glucagon binds its own receptor and couple with Gs protein activates AC and increase cAMP in liver, fat cells, heart and other tissues.
Glucagon causes hyperglycaemia by enhancing glycogenolysis and gluconeogenesis in liver.
🟢 Other hyperglycaemics..... e.g. Diazoxide, somatostatin, streptozocin.
🔴ADRS OF GENERAL ANASTHESIA🔴
During
➡️Respiratory depression
➡️Salivation
➡️Fall in bp
➡️Cardiac arrthymias
➡️Delirium
After
➡️Nausea and vomiting
➡️Organ toxicities. liver, kidney, damage.
➡️Emergence delirium
During
➡️Respiratory depression
➡️Salivation
➡️Fall in bp
➡️Cardiac arrthymias
➡️Delirium
After
➡️Nausea and vomiting
➡️Organ toxicities. liver, kidney, damage.
➡️Emergence delirium
MCQ NO 926 | Biochemistry
In biosynthesis of proteins the chain terminating codons are......
In biosynthesis of proteins the chain terminating codons are......
Anonymous Quiz
61%
UAA, UAG and UGA
13%
GCG, GCA and GCU
18%
UGG, UGU and AGU
8%
AAU, AAG and GAU