MCQ NO . 794 | Pharmacology
Which immunoglobulin is agglutinating and cytolytic
Which immunoglobulin is agglutinating and cytolytic
Anonymous Quiz
30%
A. IgG
35%
B. IgM
18%
C .IgA
17%
D . IgE
MCQ NO . 795 | Microbiology
Microorganism having the comma and S shaped form
Microorganism having the comma and S shaped form
Anonymous Quiz
30%
A. Streptococci
9%
B. Sarcina
6%
C. B.antracis
55%
D. Vibrio and Spirilla
MCQ NO 796 | Pharmacology
Among the immunising agents listed below one of them is orally administered. Identify.
Among the immunising agents listed below one of them is orally administered. Identify.
Anonymous Quiz
14%
A. Taranus toxid
13%
B. Rabies vaccine
62%
C. Poliomyelitis vaccine
10%
D. Mumps virus vaccine
MCQ NO 797 | pharmaceutical jurisprudence
List of coaltar colours permitted to be used in cosmetics is come under schedule
List of coaltar colours permitted to be used in cosmetics is come under schedule
Anonymous Quiz
12%
A. O
14%
B. P
68%
C. Q
7%
D. R
MCQ NO 798 | pharmaceutical jurisprudence
Drug Inspector is appointed under section-----of the act.
Drug Inspector is appointed under section-----of the act.
Anonymous Quiz
11%
A. 42 of IPC
70%
B. 21 of IPC
13%
C. 46 of IPC
6%
D. 31 of IPC
MCQ NO 799 | Microbiology
Which of the following microorganism is particularly dangerous to the eyes
Which of the following microorganism is particularly dangerous to the eyes
Anonymous Quiz
15%
A. E. Coli
22%
B. S. Thermophilus
49%
C. P. Aeruginosa
14%
D. S. Cerevisiae
MCQ NO 800 | Microbiology
Chemotaxis is a phenomenon that refers to:
Chemotaxis is a phenomenon that refers to:
Anonymous Quiz
45%
A) directed movement in response to a chemical stimulus
25%
B) taxonomic classification of biochemicals
24%
C) large influx of a chemical molecule within bacterial cells
6%
D) adherence of bacterial proteins to host cells
🔴DEFINITION
🔶Prostaglandin:
One of a number of hormone-like substances that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
🔶Prostaglandin E2:
One of the prostaglandins, a group of hormone-like substances that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
🔶Prostaglandin PGI2:
It is synthesized by endothelial cells lining the walls of arteries and veins; it is a potent vasodilator and a potent inhibitor of platelet aggregation.
🔶Prostaglandin:
One of a number of hormone-like substances that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
🔶Prostaglandin E2:
One of the prostaglandins, a group of hormone-like substances that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.
🔶Prostaglandin PGI2:
It is synthesized by endothelial cells lining the walls of arteries and veins; it is a potent vasodilator and a potent inhibitor of platelet aggregation.
🔴Mechanism🔴
📌 prostaglandins synthesis
◾️Arachidonic acid is a key component of phospholipids, which are themselves integral components of cell membranes. In response to many different stimuli, including various hormonal, chemical, or physical agents, a chain of events is set in motion that results in prostaglandin formation and release.
◾️ These stimuli, either directly or indirectly, result in the activation of an enzyme called phospholipase A2.
◾️This enzyme catalyzes the release of arachidonic acid from phospholipid molecules.
◾️ Depending on the type of stimulus and the enzymes present, arachidonic acid may diverge down one of several possible pathways.
◾️One enzyme, lipoxygenase, catalyzes the conversion of arachidonic acid to one of several possible leukotrienes, which are important mediators of the inflammatory process.
◾️Another enzyme, cyclooxygenase, catalyzes the conversion of arachidonic acid to one of several possible endoperoxides.
◾️The endoperoxides undergo further modifications to form prostaglandins, prostacyclin, and thromboxanes.
◾️The thromboxanes and prostacyclin have important functions in the process of blood coagulation.
📌 prostaglandins synthesis
◾️Arachidonic acid is a key component of phospholipids, which are themselves integral components of cell membranes. In response to many different stimuli, including various hormonal, chemical, or physical agents, a chain of events is set in motion that results in prostaglandin formation and release.
◾️ These stimuli, either directly or indirectly, result in the activation of an enzyme called phospholipase A2.
◾️This enzyme catalyzes the release of arachidonic acid from phospholipid molecules.
◾️ Depending on the type of stimulus and the enzymes present, arachidonic acid may diverge down one of several possible pathways.
◾️One enzyme, lipoxygenase, catalyzes the conversion of arachidonic acid to one of several possible leukotrienes, which are important mediators of the inflammatory process.
◾️Another enzyme, cyclooxygenase, catalyzes the conversion of arachidonic acid to one of several possible endoperoxides.
◾️The endoperoxides undergo further modifications to form prostaglandins, prostacyclin, and thromboxanes.
◾️The thromboxanes and prostacyclin have important functions in the process of blood coagulation.
🔴ADR OF PROSTAGLANDINS🔴
➡️Tachy systole
➡️Fetal heart rate changes
➡️Meconium passage high
➡️Rupture of uterus rarely
➡️Tachy systole
➡️Fetal heart rate changes
➡️Meconium passage high
➡️Rupture of uterus rarely
MCQ NO 801 | pharmaceutics
Which one of the folowing sweetener is ≈600 times sweeter than sucrose .
Which one of the folowing sweetener is ≈600 times sweeter than sucrose .
Anonymous Quiz
32%
(A)sucralose
18%
(B)acesulfame-k
44%
(C)aspartame
7%
(D)sodium cyclamate
MCQ NO 802 | pharmaceutics
List of direct compresible diluents used in tablet formulation is given below except
List of direct compresible diluents used in tablet formulation is given below except
Anonymous Quiz
24%
(A)hydrous lactose
29%
(B)spray dried lactose
23%
(C)anyhydrous lactose
25%
(D)starch 1500
MCQ NO 803 | pharmaceutics
Deflocculated suspensions usually have a suspend
Deflocculated suspensions usually have a suspend
Anonymous Quiz
17%
(A)With a high sedimentation rate
60%
(B)That becomes compacted and dificult to redisperse after sedimentation
17%
(C)That redisperses easily after sedimentation
5%
(D)With a low suspendabilty
MCQ NO 804 | pharmaceutics
The formulation of pharmaceutical dosage form refers to
The formulation of pharmaceutical dosage form refers to
Anonymous Quiz
51%
(A)It’s compounding
24%
(B)It’s constituents
15%
(C)It’s design
10%
(D)It’s application
MCQ NO 805 | pharmaceutics
Non-nutritive syrups for diabetic use may contain
Non-nutritive syrups for diabetic use may contain
Anonymous Quiz
35%
(A)sorbital
47%
(B)Invert syrup
13%
(C)Cane sugar
5%
(D)Milk sugar
MCQ NO 806 | pharmaceutics
Good manufacturing practice protocols in the production of pharmaceutical dosage forms ensures their
Good manufacturing practice protocols in the production of pharmaceutical dosage forms ensures their
Anonymous Quiz
7%
(A)potency
9%
(B)purity
12%
(C)quality
72%
(D)all of the above
MCQ NO 807| Pharmacology
`Essential drugs’ are:
`Essential drugs’ are:
Anonymous Quiz
15%
A. Life saving drugs
65%
B. Drugs that meet the priority health care needs of the population
14%
C. Drugs that must be present in the emergency bag of a doctor
5%
D. Drugs that are listed in the pharmacopoia of a country
MCQ NO 808 | Pharmacology
If a drug is eliminated by first order kinetics:
If a drug is eliminated by first order kinetics:
Anonymous Quiz
39%
A. A constant amount of the drug will be eliminated per unit time
24%
B. Its clearance value will remain constant
25%
C. Its elimination half life will increase with dose
12%
D. It will be completely eliminated from the body in 2 × half life period
MCQ NO 809 | Pharmacology
Monitoring plasma drug concentration is useful while using:
Monitoring plasma drug concentration is useful while using:
Anonymous Quiz
20%
A. Antihypertensive drugs
20%
B. Levodopa
47%
C. Lithium carbonate
13%
D. MAO inhibitors
MCQ NO 810 | Pharmacology
‘Addiction’ and ‘habituation’:
‘Addiction’ and ‘habituation’:
Anonymous Quiz
9%
A. Are fundamentally different phenomena
11%
B. Are produced by different set of drugs/substances
51%
C. Differ from one another by the presence or absence of physical dependence
29%
D. Differ from each other in the degree of attendant psychological dependence