Age and sex stratified incidence rates for 15 adverse events of covid-19 vaccines in eight countries:
https://pubmed.ncbi.nlm.nih.gov/35727911/
https://pubmed.ncbi.nlm.nih.gov/35727911/
A case of hypophysitis associated with SARS-CoV2 vaccination:
https://www.aaceclinicalcasereports.com/article/S2376-0605(22)00040-2/fulltext
- "SARS-CoV2 vaccine-related endocrinopathy seems indeed possible"
- "Endocrinopathies may be underestimated in post- SARS-CoV2 vaccinated population."
- "The mechanism of endocrinopathies after SARS-CoV2 vaccination is unknown."
https://www.aaceclinicalcasereports.com/article/S2376-0605(22)00040-2/fulltext
- "SARS-CoV2 vaccine-related endocrinopathy seems indeed possible"
- "Endocrinopathies may be underestimated in post- SARS-CoV2 vaccinated population."
- "The mechanism of endocrinopathies after SARS-CoV2 vaccination is unknown."
Intracranial hemorrhage in a patient with COVID-19 vaccine-induced immune thrombotic thrombocytopenia and cerebral venous thrombosis:
https://www.sciencedirect.com/science/article/pii/S1015958422007849?via%3Dihub
https://www.sciencedirect.com/science/article/pii/S1015958422007849?via%3Dihub
- "Studies have now confirmed that “original antigenic sin”, or a detrimental fixation on a suboptimal immune response, is a real problem for people who’ve gotten COVID-19 vaccines."
- "In addition to a blunted antibody response against the nucleocapsid protein, people whose immune systems are primed by vaccination appear to have impaired cellular immunity relative to those with natural immunity."
https://www.jeremyrhammond.com/2022/06/22/original-antigenic-sin-is-a-real-problem-with-covid-19-vaccines/
- "In addition to a blunted antibody response against the nucleocapsid protein, people whose immune systems are primed by vaccination appear to have impaired cellular immunity relative to those with natural immunity."
https://www.jeremyrhammond.com/2022/06/22/original-antigenic-sin-is-a-real-problem-with-covid-19-vaccines/
Jeremy R. Hammond
Original Antigenic Sin Is a Problem with COVID-19 Vaccines
Studies have confirmed that a detrimental fixation on a suboptimal immune response is a real problem for people who’ve gotten COVID-19 vaccines.
https://www.statnews.com/2022/06/13/lessons-from-earlier-pandemics-vaccine-panel-must-discuss-imprinting-among-infants-and-toddlers/
"The immune systems of infants and toddlers — the targets of the latest Covid-19 vaccination approval — are immature and developing. If an immature immune system is immunologically imprinted ... by a Covid-19 vaccine based on the original, wild-type variant that is no longer in circulation, it may fail to develop appropriate defenses when confronted — even years later — by a Covid variant or another totally different pathogen."
"The immune systems of infants and toddlers — the targets of the latest Covid-19 vaccination approval — are immature and developing. If an immature immune system is immunologically imprinted ... by a Covid-19 vaccine based on the original, wild-type variant that is no longer in circulation, it may fail to develop appropriate defenses when confronted — even years later — by a Covid variant or another totally different pathogen."
STAT
Lessons from earlier pandemics: Vaccine panel must discuss imprinting among infants and toddlers
Rather than hastening to extend emergency use authorization of Covid-19 vaccines to infants and toddlers, the VRBPAC should pause and demand more than the two hours allotted for discussion and voting.
Thalamic hemichorea after #Covidvaccination:
https://ecevr.org/DOIx.php?id=10.7774/cevr.2022.11.2.217
" ... thromboembolic thalamic stroke with severe thrombocytopenia, presence of the IgG PF-4 in the blood, negative HIPA test, and positive modified HIPA, 4–16 days after receiving the first dose of the ChAdOx1 nCoV-19 vaccine, represent ... novel immune-mediated responses ..."
"We believe that vaccine-induced prothrombotic immune thrombocytopenia (VIPIT) due to the ChAdOx1 nCoV-19 needs more extensive investigations in the future and has great importance for clinicians worldwide for rapid identification, diagnosis, and treatment of similar cases."
https://ecevr.org/DOIx.php?id=10.7774/cevr.2022.11.2.217
" ... thromboembolic thalamic stroke with severe thrombocytopenia, presence of the IgG PF-4 in the blood, negative HIPA test, and positive modified HIPA, 4–16 days after receiving the first dose of the ChAdOx1 nCoV-19 vaccine, represent ... novel immune-mediated responses ..."
"We believe that vaccine-induced prothrombotic immune thrombocytopenia (VIPIT) due to the ChAdOx1 nCoV-19 needs more extensive investigations in the future and has great importance for clinicians worldwide for rapid identification, diagnosis, and treatment of similar cases."
Subacute thyroiditis after #Covidvaccination:
https://ecevr.org/DOIx.php?id=10.7774/cevr.2022.11.2.226
" ... clinicians should be aware that subacute thyroiditis might be a probably adverse effect of COVID-19 vaccines, especially among patients presenting with neck pain following a SARS-CoV-2 vaccination."
"The mechanism of SAT following the SARS-CoV-2 vaccination remains unknown."
https://ecevr.org/DOIx.php?id=10.7774/cevr.2022.11.2.226
" ... clinicians should be aware that subacute thyroiditis might be a probably adverse effect of COVID-19 vaccines, especially among patients presenting with neck pain following a SARS-CoV-2 vaccination."
"The mechanism of SAT following the SARS-CoV-2 vaccination remains unknown."
Epstein-Barr virus reactivation after #Covidvaccination:
https://ecevr.org/DOIx.php?id=10.7774/cevr.2022.11.2.222
https://ecevr.org/DOIx.php?id=10.7774/cevr.2022.11.2.222
Leukocytoclastic vasculitis following the COVID-19 vaccination:
https://journals.sagepub.com/doi/10.1177/00185787211067379
".. may be a new vaccine-linked event, which needs further investigation and long term studies ..."
https://journals.sagepub.com/doi/10.1177/00185787211067379
".. may be a new vaccine-linked event, which needs further investigation and long term studies ..."
Post-vaccinal encephalitis with early relapse after #covidvaccination:
https://www.mdpi.com/2076-393X/10/7/1065/htm
- "One day after receiving the first dose, he cursed with malaise, headache, fever, confusion, aggressiveness, and gait alterations."
- "The patient was readmitted due to early clinical relapse four days after receiving his second dose."
"... we report the case of a patient with a clinical picture of encephalopathy of probable autoimmune etiology after vaccination with BNT162b2 (COMIRNATY) who presented an early clinical relapse after the second dose."
https://www.mdpi.com/2076-393X/10/7/1065/htm
- "One day after receiving the first dose, he cursed with malaise, headache, fever, confusion, aggressiveness, and gait alterations."
- "The patient was readmitted due to early clinical relapse four days after receiving his second dose."
"... we report the case of a patient with a clinical picture of encephalopathy of probable autoimmune etiology after vaccination with BNT162b2 (COMIRNATY) who presented an early clinical relapse after the second dose."
COVID-19 vaccination might induce postural orthostatic tachycardia syndrome (POTS): A case report
https://www.mdpi.com/2076-393X/10/7/991
" ... the patient presented with fatigue, palpitations, dizziness, and presyncope, with symptoms beginning 7 days after vaccination."
https://www.mdpi.com/2076-393X/10/7/991
" ... the patient presented with fatigue, palpitations, dizziness, and presyncope, with symptoms beginning 7 days after vaccination."
Adenomesenteritis following #covidvaccination:
https://www.mdpi.com/2227-9067/9/7/993/htm
A case of a 13-year-old girl.
- "The vaccination could act as a trigger and cause an immune-mediated inflammatory response in the gastrointestinal tract resulting in the adenomesenteritis."
- "Certainly, larger studies with a longer follow-up are needed to investigate all possible adverse effects after COVID-19 vaccination in children."
https://www.mdpi.com/2227-9067/9/7/993/htm
A case of a 13-year-old girl.
- "The vaccination could act as a trigger and cause an immune-mediated inflammatory response in the gastrointestinal tract resulting in the adenomesenteritis."
- "Certainly, larger studies with a longer follow-up are needed to investigate all possible adverse effects after COVID-19 vaccination in children."
Acute pulmonary embolism following #covidvaccination:
https://pubmed.ncbi.nlm.nih.gov/35873116/
- "Thromboembolic events can occur in patients after SARS-CoV2 mRNA vaccination."
- "The pathophysiology of SARS-CoV2 vaccine-related thromboembolic events may be caused by anti-PF4 antibodies, but is probably multifactorial."
- "How long pathogenic anti-PF4 antibodies persist and the correlations between levels of PF4-heparin antibodies and anti-SARS-CoV-2 IgG antibodies are not currently well understood."
https://pubmed.ncbi.nlm.nih.gov/35873116/
- "Thromboembolic events can occur in patients after SARS-CoV2 mRNA vaccination."
- "The pathophysiology of SARS-CoV2 vaccine-related thromboembolic events may be caused by anti-PF4 antibodies, but is probably multifactorial."
- "How long pathogenic anti-PF4 antibodies persist and the correlations between levels of PF4-heparin antibodies and anti-SARS-CoV-2 IgG antibodies are not currently well understood."
#Covidvaccination → Stroke (multiple acute infarction areas in the left temporoparietal, right temporofrontal, and right parietal cortex).
Case of a 22‐year‐old woman:
http://caspjim.com/article-1-3282-en.html
Case of a 22‐year‐old woman:
http://caspjim.com/article-1-3282-en.html
Onset of bilateral visual disturbance 6 days after #COVIDVaccination cination → corneal edema.
https://journals.lww.com/md-journal/Fulltext/2022/07220/Case_report_of_transient_corneal_edema_after.67.aspx
https://journals.lww.com/md-journal/Fulltext/2022/07220/Case_report_of_transient_corneal_edema_after.67.aspx
Fulminant hepatitis following #Covidvaccination:
https://onlinelibrary.wiley.com/doi/10.1002/ccr3.6066
- A 35-year-old man was admitted to the hospital with generalized weakness, abdominal pain, and jaundice
- He died 3 days later of disseminated intravascular coagulopathy
https://onlinelibrary.wiley.com/doi/10.1002/ccr3.6066
- A 35-year-old man was admitted to the hospital with generalized weakness, abdominal pain, and jaundice
- He died 3 days later of disseminated intravascular coagulopathy
Fulminant myocarditis after the first dose of mRNA-1273 vaccination in a patient with previous COVID-19: a case report
https://pubmed.ncbi.nlm.nih.gov/35860438/
"The mechanism of COVID-19 vaccine-associated myocarditis needs to be urgently investigated."
https://pubmed.ncbi.nlm.nih.gov/35860438/
"The mechanism of COVID-19 vaccine-associated myocarditis needs to be urgently investigated."