The synthesis of fatty acids from Acetyl-CoA is called:
Anonymous Quiz
69%
A) Lipogenesis
6%
B) Lipolysis
6%
C) Ketogenesis
15%
D) ฮฒ-Oxidation
3%
E) Steroidogenesis
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Which sequence correctly represents the pathway leading to steroid synthesis?
Anonymous Quiz
8%
A) Acetyl-CoA โ Ketone bodies โ Steroids
20%
B) Fatty acids โ Cholesterol โ Steroids
47%
C) Acetyl-CoA โ Cholesterol โ Steroids
20%
D) Triacylglycerol โ Cholesterol โ Steroids
5%
E) Amino acids โ Ketone bodies โ Steroids
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๐ฎ๐ถโ๏ธ The exam โ๏ธ๐ต๐ธ pinned ยซ๐งชOrganic ๐
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ููุฒ ู ูู ุฌุฏุงู ููุฌุงุจุชุฑ ุงูุซุงูู ุนุถููุฉ
Quiz Organic Ch.2 METABOLIC
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ูุฒุงุฑูุงุช ฺุงุจุชุฑ 3 ุนุถููุฉ ูุธุฑู (1).pdf
ุดุจุงุจ ูุฐุง ุงูุงู ุชุญุงู ููุด ู ูู ุจุงููุณุจุฉ ููProdrug ุญุงููู ุชุถุจุทูู ุฒูู ๐ซฃ๐คซ
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Compared with esters, amides are:
Anonymous Quiz
15%
A) Hydrolyzed faster
14%
B) Hydrolyzed at the same rate
57%
C) Hydrolyzed more slowly
10%
D) Resistant to metabolism
3%
E) Non above
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Reduction of ketones yields:
Anonymous Quiz
5%
A) Acids
12%
B) Aldehydes
18%
C) Primary alcohols
63%
D) Secondary alcohols
2%
E) Amines
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Which Phase II pathway mainly protects DNA, RNA and proteins from reactive metabolites?
Anonymous Quiz
6%
A) Sulfation conjugation
78%
B) GSH conjugation
8%
C) Acetylation conjugation
7%
D) Methylation conjugation
1%
E) Glycine conjugation
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Which Phase II reactions usually terminate or attenuate pharmacological activity without markedly increasing water solubility?
Anonymous Quiz
3%
A) Sulfation and glucuronidation
48%
B) Methylation and acetylation
29%
C) Glycine and glutamine conjugation
14%
D) GSH conjugation and sulfation
5%
E) O-glucuronidation and sulfation
Large glucuronide conjugates (>300 Da) are often excreted in:
Anonymous Quiz
2%
A) Sweat
0%
B) Saliva
30%
C) Urine
66%
D) Bile
2%
E) Lungs
The most common functional groups forming O-glucuronides are:
Anonymous Quiz
6%
A) Nitro and azo
13%
B) Carbonyl and imine
66%
C) Hydroxy and carboxyl groups
11%
D) Sulfoxides and sulfones
5%
E) Ketones and aldehydes
ูุง ุฌุงุจุชุฑ ุตุนุจ ุจุงููุณุจุฉ ุงูู ......
Anonymous Poll
21%
. ุงูุงูู Drug Design
69%
. ุงูุซุงูู Metabolic
10%
. ุงูุซุงูุซ Prodrug
๐1
Which of the following is true about the pKa of a weak acid?
Anonymous Quiz
49%
a. It has a high pKa value.
32%
b. It has low pka value.
9%
c. Both A and B .
10%
d. It is the pKa of the conjugate acid.
๐ฎ๐ถโ๏ธ The exam โ๏ธ๐ต๐ธ
Which of the following is true about the pKa of a weak acid?
Strong acid = decrease PKa = increase Ionized โ
Weak acid = increase PKa = decrease Ionized โ
Weak acid = increase PKa = decrease Ionized โ
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The pH of a solution of weak acid with pka value equal to 4.5, with ionized part of 3ฮง10^-3 and the free acid is 9ฮง10^-3 is
Anonymous Quiz
6%
a. 1.5
19%
b. 2.2
63%
c. 3.9
10%
d. 3
2%
e. 1
the ratio between percent of ionization and pka, which one is true:
Anonymous Quiz
11%
a. weak acid, pka=4, pH=4, percent of ionization= 90%
40%
b. weak acid, pka=4, pH=5, percent of ionization = 99%
27%
c. weak acid, pka=4, pH=5, percent of ionization = 91%
12%
d. weak acid, pka=4, pH=3, percent of ionization = 50%
10%
e. weak acid, pka=4, pH=6, percent of ionization = 93%
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What is the ratio of ephedrine to ephedrine HCl (pKa 9.6) in the intestinal tract at pH 8.0?
Anonymous Quiz
16%
A. 0.025
30%
B. 0.082
22%
C. 0.222
15%
D. 0.678
16%
E. 1
๐1
What is the percentage ionization of ephedrine HCl (pKa 9.6) in an intestinal tract buffered at pH 8.0 ..
Anonymous Quiz
27%
90.1%
6%
95%
35%
97.6%
23%
99.9%
10%
Non above
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