World Genetics
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Hi everyone, make sure to watch the video where my friend Laurent and I discuss French identity, DNA tests and population genetics in general 🇫🇷

The interview was recorded in French but it’s dubbed and subtitled in English.

https://www.youtube.com/watch?v=UfVhlq9IsB0
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🇵🇭 Five waves into the Philippines, not one

Genetic evidence shows the islands were peopled by multiple waves, not a single migration. The earliest were Negrito ancestors (in at least two branches). Later movements came from the south (including Manobo and Sama groups).

A final major wave brought Cordilleran-related people—early Basal East Asians—arriving ~8–10 thousand years ago, well before rice farming.

Cordillerans today are the least mixed and a better stand-in than Taiwanese groups for early Austronesian ancestry.

Some coastal communities (especially Sama) also show South Asian input from trade about 1,000 years ago, while Spanish ancestry in sampled lowlanders is very small.

Takeaway: The archipelago’s DNA reflects several pulses plus regional mixing, not a single “out of Taiwan” story.

Source: Larena et al., 2021. Multiple migrations to the Philippines during the last 50,000 years.
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🏜️ A deep North African lineage in the Green Sahara

Ancient DNA from two ~7,000-year-old pastoralist women at Takarkori (SW Libya) reveals a previously unknown North African lineage that split early and stayed largely isolated.

Pastoralism in the Sahara likely spread by culture, not by large population movements. The genomes show only a tiny Neanderthal signal (much less than in non-Africans) plus a small Levantine input, while ties to sub-Saharan groups during the Green Sahara were minimal.

This helps reframe Taforalt (15,000 years ago) as a mix of Levantine and deep North African ancestry rather than “Levantine + sub-Saharan.”

Takeaway: North Africa harbored a distinct, long-isolated ancestry through the Green Sahara — with herding practices arriving mainly through cultural diffusion, not mass migration.

Source: Salem et al., 2025. Ancient DNA from the Green Sahara reveals ancestral North African lineage.
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🇯🇵 A Jomon–Kamchatka mix before the Okhotsk

An early Okhotsk genome from Rebun Island (Hokkaido) shows ancestry from Jomon (the Indigenous hunter-gatherers of Japan) mixed with Kamchatka/Chukotka–related peoples from Russia’s Far East — giving the first direct genetic proof of this pre-Okhotsk mixed population.

Later Okhotsk individuals carry extra Amur Basin ancestry, but this early person does not, which helps pin down the sequence of movements into northern Japan: first Jomon + Kamchatka, then Amur.

Takeaway: Northern Japan’s ancient DNA records a two-step story — Jomon–Kamchatka mixing came before later arrivals from the Amur Basin, not one single wave.

Source: Sato et al., 2025. Genome of an early Okhotsk individual reveals ancient admixture between Jomon and Kamchatka lineages.
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🦴 A Crimean Neanderthal linked to Siberia

A tiny bone from the Starosele cave in Crimea turned out to be Neanderthal and about 45,000 years old. Collagen “fingerprinting” and mtDNA show this individual is closest to Altai (Siberian) Neanderthals — roughly 3,000 km away — hinting at long-distance links.

Stone tools at Starosele also match the Micoquian tradition seen across these regions, and climate models point to a northern corridor that would have eased movement during warmer phases.

Takeaway: Late Neanderthals were connected across Eurasia — by genes, tools, and favorable climate windows — not isolated in small local pockets.

Source: Pigott et al., 2025. A new late Neanderthal from Crimea reveals long-distance connections across Eurasia.
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🐎 Where Indo-European ancestors formed

Genetic data show the Yamnaya formed on the Dnipro–Don steppe from local hunter-gatherers mixing with people of the Caucasus–lower Volga (CLV) cline.

The CLV group provided about four-fifths of Yamnaya ancestry, and the key mixing began around 4000 BC, followed by a rapid expansion after ~3300 BC.

The authors propose that speakers of proto-Indo-Anatolian — the ancestor of Indo-European and Anatolian — were among CLV people sometime between 4400 and 4000 BC, with CLV-related ancestry later reaching Central Anatolia.

Takeaway: Indo-European origins trace to a Dnipro–Don fusion dominated by a CLV-derived ancestry, timed to the late fifth–early fourth millennium BC.

Source: Lazaridis et al., 2025. The genetic origin of the Indo-Europeans.
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🇮🇩 Borneo’s deep foragers

Genetic evidence shows the Punan form a distinct cluster with shared ancestry across subgroups — a biological unity, not just a cultural label.

Their core lineage split before Proto-Austronesians, and the Punan Batu carry no Austronesian gene flow, pointing to ancestry rooted in northeast Borneo for over 7,500 years.

Nearby farming groups (Dusun/Lundayeh) show a sizable Mainland Southeast Asian component, but the Punan lack this signal. A tiny ~0–2% link to the ancient Leang Panninge hunter-gatherer appears in models but remains weak.

Takeaway: Punan ancestry is ancient and locally rooted, predating the Austronesian expansion and staying comparatively insulated from later farmer-related gene flow.

Source: Kusuma et al., 2023. Deep ancestry of Bornean hunter-gatherers supports long-term local ancestry dynamics.
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🇲🇽 Mexico City is mostly Indigenous, genetically

DNA from Mexico City shows people are, on average, about two-thirds Indigenous and about one-third European, with a small African component.

The X chromosome carries more Indigenous ancestry than the rest of the genome, which fits a history with more Indigenous women and more European men contributing to today’s population.

The dataset also helps make medical genetics work better for people with high Indigenous Mexican ancestry.

Takeaway: Mexico City’s genome reflects a predominantly Indigenous heritage shaped by sex-biased mixing during and after colonization.

Source: Ziyatdinov et al., 2023. Genotyping, sequencing and analysis of 140,000 adults from Mexico City.
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🏛️ Rome was a genetic crossroads

Genomes from 127 people at 29 sites around Rome, spanning 12,000 years, reveal two big shifts: first with incoming Neolithic farmers, then before the Iron Age with added Steppe ancestry.

By Rome’s founding, locals already looked like modern Mediterranean people. In the Imperial era, most newcomers traced to the eastern Mediterranean and Near East; later, in Late Antiquity, ancestry shifted back toward central and northern Europe. The constant theme is high diversity through time.

Takeaway: Ancient Rome drew people from across the Mediterranean and beyond, and its DNA mirrors those changing connections.

Source: Antonio et al., 2019. Ancient Rome: A genetic crossroads of Europe and the Mediterranean.
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🛡️ Roman soldiers in a well at Mursa?

Archaeologists found seven adult men stacked in a reused well at Roman Mursa (Osijek, Croatia). Radiocarbon dates place the burial in the mid-3rd century CE, during the Crisis of the Third Century. The bones show violent injuries consistent with battle, and isotopes point to a grain-heavy diet with limited meat, which fits army rations.

Ancient DNA shows mixed, non-local ancestries, not continuous with the earlier local Iron Age group, matching the makeup of imperial units. Together, the evidence points to victims of a military event, most likely tied to the 260 CE battle of Mursa.

Takeaway: This mass grave likely holds Roman soldiers from a single violent episode in the mid-3rd century, with DNA revealing a diverse army drawn from across the empire.

Source: Novak et al., 2025. Multidisciplinary study of human remains from the 3rd century mass grave in the Roman city of Mursa, Croatia.
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⛰️ Early Tibetans: local roots with southern links

Ancient DNA from 16 people at the high-altitude Mabu Co site shows a stable southern-plateau ancestry from ~4,400–3,500 years ago, with periodic contacts from outside.

Part of the community carries a Basal Asian (Xingyi-related) signal from southwestern China, hinting at movement along the Tibetan–Yi corridor. Some individuals also show input from Yellow River farmers, likely tied to millet farming.

Maternal lineages are diverse, while Y-chromosomes are more uniform — consistent with male-biased gene flow from lowlands. The high-altitude adaptation gene EPAS1 is present and its frequency shifts over time between women and men.

Takeaway: Early Tibet wasn’t a single migration. A core plateau ancestry persisted while selective pulses from the south and lowlands reshaped the gene pool — alongside ongoing high-altitude adaptation.

Source: Ran et al., 2025. Ancient genomes reveal basal Asian ancestries and dynamic population interactions over time on the southern Tibetan Plateau.
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🇲🇦 How the Maghreb became Neolithic

Ancient DNA from Morocco shows that early farmers in northwest Africa came largely from Iberia, bringing crops and animals across the Strait of Gibraltar around 7,400–6,900 years ago.

Those earliest Neolithic people carry mostly European farmer ancestry with a local Maghrebi layer, while nearby hunter-gatherer groups (Maghrebi ancestry from Taforalt) continued alongside them.

A bit later, during the Middle Neolithic, a strong Levant-related ancestry appears and mixes with local groups, matching the spread of pastoralism.

Takeaway: Farming in northwest Africa started with Iberian migrants, then the region blended local Maghrebi and Levant-related ancestries into today’s North African genetic mosaic.

Source: Simões et al., 2023. Northwest African Neolithic initiated by migrants from Iberia and Levant.
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🇨🇺 Cuba’s three-way ancestry

Genome data from 860 Cubans shows a three-way mix: mostly European on average (about 70%), with African and smaller Native American components.

The east carries more African and Native American ancestry than the west. The mixing was sex-biased overall, with more European male and African/Native American female input.

Source populations point to Iberia for the European part, West-Central Africa and the Bights of Benin/Biafra for the African part, and South American/Mesoamerican groups for the Native American part.

Timing analyses suggest early-colonial Indigenous and African inputs, plus a later African pulse in the east consistent with Haitian migration.

Takeaway: Cuba’s DNA is regional and layered, shaped by early colonial mixing and later movements, not a single event.

Source: Fortes-Lima et al., 2018. Exploring Cuba’s population structure and demographic history using genome-wide data.
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🇮🇹 Picenes on the Adriatic had more Steppe ancestry

Ancient DNA from Picene cemeteries shows they were broadly similar to other Italic Iron Age peoples, but those on the Adriatic side (Picenes, Apulia) carried more Yamnaya/Steppe-related ancestry than groups on the Tyrrhenian side (Etruscans, early Romans).

The pattern fits steady contacts across the Adriatic and a slightly different path of Bronze–Iron Age gene flow into central Italy. Individual outliers reveal links to the Eastern Mediterranean and Central/Northern Europe, highlighting high mobility.

In Late Antiquity, nearby burials shift strongly toward Near Eastern–related ancestry, matching the demographic pull of the Roman Empire.

Takeaway: Central Italy’s Iron Age shared a common base, but the Adriatic corridor brought in extra Steppe ancestry and more Balkan connections — later reshaped by Imperial-era Near Eastern influx.

Source: Ravasini et al., 2024. The Genomic portrait of the Picene culture: new insights into the Italic Iron Age and the legacy of the Roman expansion in Central Italy.
🏛️ Corinthian DNA in an Epirus colony

Ancient genomes show that Amvrakia’s first settlers were mostly people from the Corinth area, not locals. The earliest Amvrakians share long DNA chunks with individuals from Tenea near Corinth, which fits a 7th-century BCE foundation by migrants from the metropolis.

Through the Classical and Hellenistic periods the city’s gene pool stays broadly continuous, with only modest shifts. A direct contribution from the nearby Late Bronze Age population is not clearly detected at the founding stage, suggesting culture and people moved together from Corinth.

Takeaway: Amvrakia’s origin story is genetic as well as cultural — founded mainly by Corinthians, then maintained with local continuity over time.

Source: Psonis et al., 2025. Genetic affinities between an ancient Greek colony and its metropolis: the case of Amvrakia in western Greece.
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🪆 Slavic ancestry across today’s Europe

Ancient DNA ties the 6th–8th century movements from northeastern Europe to the ancestry seen in many modern groups. Today, Slavic-speaking populations carry the highest Slavic-period (SP) ancestry—especially Ukraine, Belarus, and Poland.

In Germany, there’s a sharp contrast: Sorbs in Upper Lusatia retain very high SP ancestry (~88%), while nearby German-speaking Saxony averages ~40%.

Across the Balkans, SP ancestry is widespread but mixed with local layers, and it tapers toward Greece and Albania.

Overall, SP ancestry forms a north-to-south and west-to-south gradient, strongest around the Baltic–Polish–Belarusian zone and decreasing toward Central Europe and the Mediterranean.

Takeaway: The Slavic expansions left a dominant genetic imprint in eastern Central & Eastern Europe, with gradients into neighboring non-Slavic groups—mirroring early medieval migrations and subsequent local mixing.

Source: Gretzinger et al., 2025. Ancient DNA connects large-scale migration with the spread of Slavs.
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🏜️ Tarim mummies were isolated locals — Tocharian came from the north

Ancient DNA splits Xinjiang into two stories. In the Tarim Basin (south), the earliest Bronze Age people (~2100–1700 BC, n=13) formed a genetically isolated local population, best modeled as mostly Ancient North Eurasian with a smaller ancient Northeast Asian component — and no detectable Afanasievo or BMAC ancestry.

By contrast, in the Dzungarian Basin (north) the Early Bronze Age communities show strong Afanasievo steppe ancestry mixed with locals. That northern steppe profile matches the expected vector for Tocharian, the early Indo-European language later attested in Xinjiang.

Takeaway: The famous Tarim mummies were not steppe migrants and likely not Tocharian speakers. Tocharian most plausibly arrived via Afanasievo-derived groups in Dzungaria, while the Tarim people represent a distinct local lineage.

Source: Zhang et al., 2021. The genomic origins of the Bronze Age Tarim Basin mummies.
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🗿 How Neanderthals disappeared: slow mixing, not sudden doom

A new model shows that repeated small arrivals of Homo sapiens into small, scattered Neanderthal groups could, by gene flow alone, replace most Neanderthal DNA in ~10,000–30,000 years.

The math works with tiny per-episode inputs (~0.8–8% newcomers each cycle), matching the archaeological window and what we see today — small Neanderthal traces persisting in non-Africans without needing a catastrophe or big selective advantage.

Takeaway: Neanderthals may have faded mainly through steady admixture with incoming modern humans, not a single extinction event.

Source: Amadei et al., 2025. A simple analytical model for Neanderthal disappearance due to genetic dilution by recurrent small-scale immigrations of modern humans.
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