Covid19 Proportional Vaccine Adoption [USA]
#Covid #Covid19 #Corona #Coronavirus #Omicron
> We can see that Americans are done with the vaccine, so far only 21% booster uptake, Israel at 46%, and Germany at 39%.
> Germany seems to be going up faster than previous doses.
@USMortality
#Covid #Covid19 #Corona #Coronavirus #Omicron
> We can see that Americans are done with the vaccine, so far only 21% booster uptake, Israel at 46%, and Germany at 39%.
> Germany seems to be going up faster than previous doses.
@USMortality
US states with a higher fully vaccinated #Covid19 population, saw an increase in all-cause mortality in Q4/2021 compared to Q4/2020!
Slight positive Pearson correlation is visible R2=0.22, p=0.00.
1) When comparing mortality and the impact of vaccination from an epidemiological perspective, it is important to look at similar time periods and then assess the impact of the vaccines.
2) Some jump to early conclusions, when just looking at a single time period.
3) same chart with Q4/2020 data. As we can clearly see, there was already a strong difference/slope in mortality even without any vaccination.
Likely explanation for this are other con-founders such as, general health, drug use, co-morbidities, obesity, etc.
Hence it is important to compare the change in mortality after the vaccination has been introduced to asses it's impact.
If you want to see the individual states https://www.usmortality.com @USMortality
Slight positive Pearson correlation is visible R2=0.22, p=0.00.
1) When comparing mortality and the impact of vaccination from an epidemiological perspective, it is important to look at similar time periods and then assess the impact of the vaccines.
2) Some jump to early conclusions, when just looking at a single time period.
3) same chart with Q4/2020 data. As we can clearly see, there was already a strong difference/slope in mortality even without any vaccination.
Likely explanation for this are other con-founders such as, general health, drug use, co-morbidities, obesity, etc.
Hence it is important to compare the change in mortality after the vaccination has been introduced to asses it's impact.
If you want to see the individual states https://www.usmortality.com @USMortality
JUST IN: New analysis of all-cause mortality data from Massachussets, acquired through a FOIA, shows that only 6% of the 39k all-cause deaths (acd) in the first wave and 3% of the 48k acd have #COVID19 listed as the main cause of death on the death certificate!
Even when just looking at COVID-19 deaths mentioned on the death certificate, it makes up 30% and 13% respectively for each wave.
NPI's had little to no impact.
@USMortality, Full analysis: https://metatron.substack.com/p/the-definitive-guide-to-covid-and
Even when just looking at COVID-19 deaths mentioned on the death certificate, it makes up 30% and 13% respectively for each wave.
NPI's had little to no impact.
@USMortality, Full analysis: https://metatron.substack.com/p/the-definitive-guide-to-covid-and
BIG USA All-Cause Age-Adjusted Mortality Update!
> The US is now going into seasonal appearing normal mortality pattern, that is just a statistical anomaly, caused by the pull forward effect in 85+
> 25-74 still in significant excess!
#COVID #Covid19 #Corona #LockdownsKill
@USMortality
> The US is now going into seasonal appearing normal mortality pattern, that is just a statistical anomaly, caused by the pull forward effect in 85+
> 25-74 still in significant excess!
#COVID #Covid19 #Corona #LockdownsKill
@USMortality
US Age-Adjusted All-Cause Mortality Update!
> Year-to-date, first 18 weeks, are as bad as it can get:
> 2020: +7.7%
> 2021: +15.8%
> 2022: +17.8%*
*adjusted for delay in reporting
#Covid #Covid19 #Corona #Coronavirus
@USMortality
> Year-to-date, first 18 weeks, are as bad as it can get:
> 2020: +7.7%
> 2021: +15.8%
> 2022: +17.8%*
*adjusted for delay in reporting
#Covid #Covid19 #Corona #Coronavirus
@USMortality
The confidence intervals for Pfizer's pediatric COVID-19 vaccine are crazy.
> Almost -400% (!!) efficacy lower end of the 95% CI.
> This could mean that it is within likelihood that vaccinated children have a almost 4x greater chance of getting sick with #Covid19.
@USMortality
> Almost -400% (!!) efficacy lower end of the 95% CI.
> This could mean that it is within likelihood that vaccinated children have a almost 4x greater chance of getting sick with #Covid19.
@USMortality
In Germany we are seeing almost 1,000 #covid19 deaths now per week! That's 10x higher than in the last 2 years without the vaccines!
CFR is stable at 0.12% and Cases are coming down from their latest record summer wave.
@USMortality
CFR is stable at 0.12% and Cases are coming down from their latest record summer wave.
@USMortality
Is the US about to see another summer #covid19 death wave?
Cases are at similar levels as last year, while CFR is at 0.44%...
@USMortality
Cases are at similar levels as last year, while CFR is at 0.44%...
@USMortality
All-Cause Deaths in the last 4 weeks, in Germany rise to the highest levels since 2000!
> 9,233 more people have died than expected!
> RKI only reports 972 deaths for W 27 & 28 as #COVID19 related! Other weeks not in yet.
> Latest week is +16% excess, while YTD at +5%.
@USMortality
> 9,233 more people have died than expected!
> RKI only reports 972 deaths for W 27 & 28 as #COVID19 related! Other weeks not in yet.
> Latest week is +16% excess, while YTD at +5%.
@USMortality
University of Oxford has updated its covid policy tracker to distinguish between #COVID19 stringency for unvaccinated & vaccinated.
Here's a map of countries that still discriminate based on individuals health status, which is unscientific and a human rights violation.
@USMortality
Here's a map of countries that still discriminate based on individuals health status, which is unscientific and a human rights violation.
@USMortality
Weekly US #COVID19 update:
> Cases are lower this week, about in between 2020 and 2021 levels.
> Deaths are lower than '20 & '21, but slowly rising...
> CFR at about 0.5%, just started to rise again slightly...
@USMortality https://www.usmortality.com
> Cases are lower this week, about in between 2020 and 2021 levels.
> Deaths are lower than '20 & '21, but slowly rising...
> CFR at about 0.5%, just started to rise again slightly...
@USMortality https://www.usmortality.com
🔥 New German Study shows that up to 99.4% (Mid: 98.9%, [97.9% - 99.4%]) of the German population have antibodies against the #COVID19 spike protein.
Source: https://t.co/tikL1qp7jN
@USMortality
Source: https://t.co/tikL1qp7jN
@USMortality
On July 1st the US had 88% of its seniors fully vaccinated against #Covid19. So what happened the year after that?
Excess Mortality hit another high surpassing the previous season by 12,300 excess deaths, a total of 344,525 people died.
Only the 85+ age bin had about 30k less excess death (likely pull forward effect); In contrast the other two age bins had each excess of 20k over the previous season.
https://web.archive.org/web/20210701012041/https://www.nytimes.com/interactive/2020/us/covid-19-vaccine-doses.html
https://www.usmortality.com/deaths/excess-seasonal-cumulative/united-states
@USMortality
Excess Mortality hit another high surpassing the previous season by 12,300 excess deaths, a total of 344,525 people died.
Only the 85+ age bin had about 30k less excess death (likely pull forward effect); In contrast the other two age bins had each excess of 20k over the previous season.
https://web.archive.org/web/20210701012041/https://www.nytimes.com/interactive/2020/us/covid-19-vaccine-doses.html
https://www.usmortality.com/deaths/excess-seasonal-cumulative/united-states
@USMortality
🔥 BREAKING 🚨 - UK ONS All-Cause Mortality Data for England Reveals:
‼️ The vaccine has never significantly protected the vulnerable 70+ from death!
‼️ The vaccine seems to lead to more deaths in 2022+!
#COVID19 #Covid #AllCause #ONS #DiedSuddendly #Corona #Coronavirus @USMortality
Read the full analysis - for free - on my substack:
https://usmortality.substack.com/p/covid-19-vaccine-efficacy-against
‼️ The vaccine has never significantly protected the vulnerable 70+ from death!
‼️ The vaccine seems to lead to more deaths in 2022+!
#COVID19 #Covid #AllCause #ONS #DiedSuddendly #Corona #Coronavirus @USMortality
Read the full analysis - for free - on my substack:
https://usmortality.substack.com/p/covid-19-vaccine-efficacy-against
I have verified (blasted) the published Megahit assemblies by McKernan et al. (@Kevin_McKernan
) against the SV40 promoter sequence (317bp).
Here's respectively the longest matching contig:
- Pfizer 1: Identities = 245/245 (100%), Gaps = 0/245 (0%); 77.3% match
- Pfizer 2: Identities = 245/245 (100%), Gaps = 0/245 (0%); 77.3% match
- Moderna 1: Identities = Identities = 67/67 (100%), Gaps = 0/67 (0%); 21.1% match
- Moderna 2: Identities = 317/317 (100%), Gaps = 0/317 (0%); 100% match
While Megahit was not able to assemble the entire SV40 sequence with the Pfizer 1&2 and Moderna 1 samples, it found a 100% match against the Moderna 2 sample!
My conclusion, while I could not verify the original SARS2 sequence - in this case I agree with McKernan et al., and the SV40 promoter appears to be present in the COVID-19 vaccines.
Sources & Code:
- Samples from Study: https://osf.io/b9t7m/
- SV40: https://snapgene.com/plasmids/basic_cloning_vectors/SV40_promoter opened in SnapGene Viewer, saved as .fa file.
- Code for each sample:
#Covid #Covid19 #Pfizer #Moderna #DNA #mRNA
) against the SV40 promoter sequence (317bp).
Here's respectively the longest matching contig:
- Pfizer 1: Identities = 245/245 (100%), Gaps = 0/245 (0%); 77.3% match
- Pfizer 2: Identities = 245/245 (100%), Gaps = 0/245 (0%); 77.3% match
- Moderna 1: Identities = Identities = 67/67 (100%), Gaps = 0/67 (0%); 21.1% match
- Moderna 2: Identities = 317/317 (100%), Gaps = 0/317 (0%); 100% match
While Megahit was not able to assemble the entire SV40 sequence with the Pfizer 1&2 and Moderna 1 samples, it found a 100% match against the Moderna 2 sample!
My conclusion, while I could not verify the original SARS2 sequence - in this case I agree with McKernan et al., and the SV40 promoter appears to be present in the COVID-19 vaccines.
Sources & Code:
- Samples from Study: https://osf.io/b9t7m/
- SV40: https://snapgene.com/plasmids/basic_cloning_vectors/SV40_promoter opened in SnapGene Viewer, saved as .fa file.
- Code for each sample:
makeblastdb -in PbiV1-cs-Megahit-assem.fa -dbtype nucl
blastn -query sv40.fa -db PbiV1-cs-Megahit-assem.fa -evalue 1 -task megablast > Pfi1.crunch
#Covid #Covid19 #Pfizer #Moderna #DNA #mRNA
OSF
Sequencing of bivalent Moderna and Pfizer mRNA vaccines reveals nanogram to microgram quantities of expression vector dsDNA per…
Several methods were deployed to assess the nucleic acid composition of four vials of the Moderna and Pfizer bivalent mRNA vaccines. Two vials from each vendor were evaluated with Illumina sequencing, qPCR, RT-qPCR, Qubit™ 3 fluorometry and Agilent Tape Station™…