the replacement of lost tissue by granulation tissue which
matures to form scar tissue

These are cells which have a continuous turn over by programmed division of stem cells

Their
chances of regeneration are good

they don
not have the capacity to proliferate

The word healing refers to the body replaced the destroyed tissue by living tissue

Healing by fibrosis is inevitable when the surrounding specialized cells do not possess the
capacity to proliferate

The capacity of a tissue for regeneration depends on the type and severity of the damage

A wound in which only the lining epithelium is affected heals exclusively by regeneration.

wounds that extend through the basement membrane to the connective tissue, for
example, the dermis in the skin or the sub-mucosa in the gastrointestinal tract, lead to the
formation of granulation tissue and eventual scarring.

This is characterized by proliferation of fibroblasts and an in growth of new blood vessels
into the area of injury, with a variable number of inflammatory cells

Fibroblasts actively synthesize and secrete extra-cellular matrix components, including
fibronectin, proteoglycans, and collagen types I and III

The synthesis of collagen by fibroblasts begins within 24
hours of the injury although its deposition in the tissue is not apparent until 5 days

This type 2 collagen is responsible for providing the tensile strength of the matrix in a scar

With further healing, there is an decrease in extracellular constituents, mostly collagen

With further healing, there is a decrease in the number of active fibroblasts and new vessels

In wound primary healing ,definitely important is

healing by first intention, which is incorrect?

The following accours during the first 24 h in primary intention, except

.