MCQ/Cancer Chemotherapy

الأجوبة الصحيحة تحتها خط

1. Methotrexate is:
a) A purine antagonist
b) A folic acid antagonist
c) An antibiotic
d) An alkylating agent

2. Tick the antibiotic for cancer chemotherapy:
a) Cytarabine
b) Doxorubicin
c) Gentamycin
d) Etoposide

3. Fluorouracil belongs to:
a) Antibiotics
b) Antimetabolites
c) Plant alkaloids
d) Bone marrow growth factor


4.Tick the action mechanism of anticancer drugs belonging to plant alkaloids:
a) Inhibition of DNA-dependent RNA synthesis
b) Cross-linking of DNA
c) Mitotic arrest at a metaphase
d) Nonselective inhibition of aromatases

5.General contraindications for anticancer drugs are:
a) Depression of bone marrow
b) Acute infections
c) Severe hepatic and/or renal insufficiency
d) All of the above

6.Action mechanism of methotrexate is:
a) Inhibition of dihydrofolate reductase
b) Activation of cell differentiation
c) Catabolic depletion of serum asparagine
d) All of the above

7.Tick the anticancer drug belonging to inorganic metal complexes:
a) Dacarbazine
b) Cisplatin
c) Methotrexate
d) Vincristine

8.Tick the indication for estrogens in oncological practice:
a) Leukemia
b) Cancer of prostate
c) Endometrial cancer
d) Brain tumors

9.Enzyme drug used for acute leukemia treatment:
a) Dihydrofolate reductase
b) Asparaginase
c) Aromatase
d) DNA gyrase

10.All of the following drugs are derivatives of nitrosoureas, EXCEPT:
a) Carmustine
b) Vincristine
c) Lomustine
d) Semustine

11.Tick the group of drugs used as subsidiary medicines in cancer treatment:
a) Cytoprotectors
b) Bone marrow growth factors
c) Antimetastatic agents
d) All of the above

12.Tick the estrogen inhibitor:
a) Leuprolide
b) Tamoxifen
c) Flutamide
d) Anastrozole

13.Tick the anticancer drug of plant origin:
a) Dactinomycin
b) Vincristine
c) Methotrexate
d) Procarbazine

14.Tick the anticancer drug, a pyrimidine antagonist:
a) Fluorouracil
b) Mercaptopurine
c) Thioguanine
d) Methotrexate

15.All of the following effects are disadvantages of anticancer drugs, EXCEPT:
a) Low selectivity to cancer cells
b) Depression of bone marrow
c) Depression of angiogenesis
d) Depression of immune system

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