Atherosclerosis alone accounts for less than half of all deaths in the western world

:men are much more prone to atheroma and its consequences than women that's because
His protective hormones

All of these are major factor predispose for atherosclerosis expete

SMCs also synthesize
collagen, elastin and glycoproteins to form mature fibro-fatty atheroma

the accumulation of foamy cells appear macroscopically as fibrous streaks,

Thrombosis is a complication of early -stage atherosclerosis

The atheroma plaque may be dark if lipid content more

Hyaline arteriolosclerosis:-seen in elderly patients who are hypertensive, diabetic only

systemic necrotizing vasculitis which induced by immune complexes, these
complexes found accumulate in vessel walls by deposition from circulation, by in
situ formation or by combination of these mechanism.

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All are true regard to Hyperplastic arteriolosclerosis

any organ or tissue of the body
may be affected except kidney and aorta in Polyarteritis nodosa

Regard toThe clinical signs and symptoms of Polyarteritis nodosa all true except:

Clinical diagnosis depend on biopsy of suspected areas of involvement especially
kidney and smooth muscles.

Wegener's granulomatosis:-
It's a disease of small to mdedium-sized arteries, the type of vasculiltis is necrotizing only .

clinical signs and symptoms ofWegener's granulomatosis is very similar to PAN but the lung is involved.

Microscopic polyangitis:-
This type of necrotizing vasculitis generally affects larger vessels than PAN

Microscopic polyangitis It's usually wide spread but especially the skin, necrotizing glomerulonephritis
and pulmonary capillaries are common