All the essential ingredients to make the DNA and RNA underpinning life on Earth have been discovered in samples collected from the asteroid Ryugu, scientists said Monday.

It is proposed that happiness be classified as a psychiatric disorder and be included in future editions of the major diagnostic manuals under the new name: major affective disorder, pleasant type. In a review of the relevant literature it is shown ...

Exclusive: Jonathan Powell thought Tehran’s ‘surprising’ offer on its nuclear programme could prevent rush to war, sources say

It ran for ~5 hours and got 1 tok/s. Another ~3 hours of optimizing and it's at 4.74 tok/s using 5.9GB RAM

Hi! If you like this piece and want to support my work, please subscribe to my premium newsletter. It’s $70 a year, or $7 a month, and in return you get a weekly newsletter that’s usually anywhere from 5000 to 185,000 words, including vast, extremely detailed…

GPT-5.4 mini and nano are smaller, faster versions of GPT-5.4 optimized for coding, tool use, multimodal reasoning, and high-volume API and sub-agent workloads.

AI coding tools are optimising the wrong thing and nobody wants to hear it. Writing code was already fast. The bottleneck is everything else: unclear requirements, review queues, terrified deploy cultures, and an org chart that needs six meetings to decide…

GPU-accelerated terminal board that puts all your sessions on an infinite canvas - peters/horizon

The data layer for AI agents. Memory that evolves, state that recovers, context that stays current. Open-source SDK, local-first SQLite, no API keys.

Earlier this year, we shared an update on our renewed focus for VR and Horizon. We are separating the two platforms so each can grow with greater focus, and... - 1369435

A light-weight and powerful meta-prompting, context engineering and spec-driven development system for Claude Code by TÂCHES. - gsd-build/get-shit-done

Companies allowed more harmful content on user’s feeds, knowing their algorithms ran on outrage, BBC hears.

The Den is a curated cohort community for early-stage founders — structured accountability, honest peer support, and a place that actually feels like yours.

Use Garry Tan's exact Claude Code setup: 23 opinionated tools that serve as CEO, Designer, Eng Manager, Release Manager, Doc Engineer, and QA - garrytan/gstack

We critically examine the limitations of current AI models in achieving autonomous learning and propose a learning architecture inspired by human and animal cognition. The proposed framework...

A tool for running on-premises large language models on non-public data