Today, the U.S. Food and Drug Administration is announcing its intent to take decisive steps to restrict GLP-1 active pharmaceutical ingredients (APIs) intended for use in non-FDA-approved compounded drugs that are being mass-marketed by companies

A Farcaster mini app reframing Black History Month as a GitHub-style dependency tree.

His departure came days after the company cut 30 percent of the staff. He will be replaced in the interim by Jeff D’Onofrio, the chief financial officer, the company said.

Contribute to localgpt-app/localgpt development by creating an account on GitHub.

AI eliminated the natural barrier to entry that let OSS projects trust by default. People told me to do something rather than just complain. So I did. Introducing Vouch: explicit trust management for open source. Trusted people vouch for others. https://t.co/Ift5qOnani…

It’s been talked about for a while (in fact I covered this 6 years ago), but a lot of things have been said about the potential collapse of the Atlantic Gulf Stream, also known as the Atlantic Meridional Overturning Circulation or AMOC. This global current…

Leak show feds tracking anti-ICE Reddit users like "Budget-Chicken-2425"

Substack said that customer data was accessed in October 2025 but wasn't discovered until early February.

Material Expressive is here!

I want to share some thoughts on my recent experience with OpenClaw. Over the past year, I’ve been actively using Claude Code for development. Many people believed AI could already assist with programming—seemingly replacing programmers—but I never felt it…

The real risk for American broadcasters is not that dissent will be visible. It is that audiences will start assuming anything they do not show is being hidden

DoNotNotify is now open source. View the source code, contribute, and help improve the Android notification manager.

As the New START treaty curbing the US and Russian nuclear weapons programs expires, the work we do here in the red centre has become more important than ever before.

What if this is as good as software is ever going to be? What if AI stops getting better and what if people stop caring?

Bitcoin tumbled below $61,000, as the unwinding of leveraged bets and broader market turbulence deepened a selloff that has wiped out all of the gains since President Donald Trump’s election set off a speculative rush into cryptocurrencies.

How I obtained my own AS number and IPv6 prefix, set up a FreeBSD BGP router with FRR, and built a tunnel overlay to bring globally routable addresses to servers that already have provider-assigned IPv6 - using dual-FIB policy routing to make both coexist.

Approximately 212 RFCs so far, starting with RFC 269, contain the terms `foo', `bar', or `foobar' as metasyntactic variables without any proper explanation or definition. This document rectifies that deficiency. This memo provides information for the Internet…