There are 3 species of Tryoanosoma that can infected man these are

*Description: African trypanosomes remain exclusively extracellular,

Final host of Trypanosoma gambiense: Human epimastigote

Life stages of Trypanosoma rhodesiense : amastigote , promastigote epimastigote& trypamastigote.

Diagnostic stage of Trypanosoma rhodesiense: trypomastigote only

Disease :Sleeping sickness or African trypanosomiasis.

Intermediate host : Tse-tse fly genus Glossina palpalis (epimastigote).

Tse-tse fly genus Glossina morsitans
(epimastigote)

Description: Intracellular parasite have ability to invade tissues

*Habitat or site of infection: firstly in blood & tissue of reticuloendothelial system especially lymph nodes & spleen.

Habitat or site of infection In Trypanosoma cruzi : blood & tissue especially cardiac muscle

Final host of Trypanosoma cruzi: Human(amastigote / Metacyclic trypomastigotes,)

Intermediate host of Cruzi: Reduvid bug genus Triatomine (epimastigote).

Disease: chaga’s disease or American trypanosomiasis

Diagnostic stages of cruzi : Trypomastigte in tissue and Amastigote in blood

Three types of
development in the insect vector in trypanosoma

when the vector feeds, (e g. Trypanosoma gambiense) transmitted by vectors such as the tsetse fly.

transmitted by insects such as the reduvid bugs.

First stage on Pathogensity of T. rhodesiense & T. gambiense : initial haemolymphatic stage