Maxemo EMREE 26-27
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🔬 Today's Test: EMERGENCY MEDICINE
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A 37 y/o M with HIV on ART presents with progressive gynecomastia, a buffalo hump, hollowed cheeks, and dyslipidemia. The medication class responsible for this syndrome is most known to induce which metabolic abnormality?
Anonymous Quiz
6%
Hypocalcemia
81%
Insulin resistance
6%
Hyperuricemia
6%
Hypothyroidism
Maxemo EMREE 26-27
A 37 y/o M with HIV on ART presents with progressive gynecomastia, a buffalo hump, hollowed cheeks, and dyslipidemia. The medication class responsible for this syndrome is most known to induce which metabolic abnormality?
💡 EXPLANATION:
Protease inhibitors can cause lipodystrophy syndrome, altering adipocyte function and glucose transporters. This leads to peripheral insulin resistance, hyperglycemia, dyslipidemia, and characteristic fat redistribution.
A 68 y/o M presents with worsening confusion, polyuria, and 7 kg weight loss over 3 weeks. Labs show severe hypercalcemia (Ca2+ 3.05 mmol/L) and a suppressed PTH level (8 pg/mL). What is the most likely cause of his presentation?
Anonymous Quiz
18%
Primary hyperparathyroidism
76%
Occult malignancy
6%
Vitamin D toxicity
0%
Thiazide-induced hypercalcemia
Maxemo EMREE 26-27
A 68 y/o M presents with worsening confusion, polyuria, and 7 kg weight loss over 3 weeks. Labs show severe hypercalcemia (Ca2+ 3.05 mmol/L) and a suppressed PTH level (8 pg/mL). What is the most likely cause of his presentation?
💡 EXPLANATION:
Severe hypercalcemia with suppressed PTH and significant weight loss in an elderly patient strongly indicates a PTH-independent cause, most commonly an occult malignancy producing PTH-related peptide (PTHrP).
A 65M with diaphoresis presents with 2 hours of substernal chest pain. His ECG shows ST elevation in leads II, III, and aVF. What is the most likely diagnosis?
Anonymous Quiz
10%
Anterior wall myocardial infarction
90%
Inferior wall myocardial infarction
0%
Lateral wall myocardial infarction
0%
Acute pericarditis
Maxemo EMREE 26-27
A 65M with diaphoresis presents with 2 hours of substernal chest pain. His ECG shows ST elevation in leads II, III, and aVF. What is the most likely diagnosis?
💡 EXPLANATION:
ST elevation in leads II, III, and aVF localizes the infarct to the inferior wall of the heart. Anterior MI involves V1 to V4, lateral MI involves leads I, aVL, V5, and V6, and acute pericarditis typically causes diffuse ST elevation.
A child presents with a bright red rash on both cheeks giving a classic slapped cheek appearance. What is the most likely diagnosis?
Anonymous Quiz
64%
Erythema infectiosum
32%
Scarlet fever
5%
Measles
0%
Rubella
Maxemo EMREE 26-27
A child presents with a bright red rash on both cheeks giving a classic slapped cheek appearance. What is the most likely diagnosis?
💡 EXPLANATION:
Erythema infectiosum, also called fifth disease, is caused by parvovirus B19. The characteristic slapped cheek rash is pathognomonic.
A 45-year-old woman presents with fatigue, weight gain, and cold intolerance. Labs show TSH 14 mIU per L and free T4 0.5 ng per dL. No goiter is palpated. What is the most appropriate next step?
Anonymous Quiz
50%
Start levothyroxine therapy
15%
Repeat TSH and free T4 in 4 weeks
10%
Order a thyroid ultrasound
25%
Check for anti TPO antibodies
Maxemo EMREE 26-27
A 45-year-old woman presents with fatigue, weight gain, and cold intolerance. Labs show TSH 14 mIU per L and free T4 0.5 ng per dL. No goiter is palpated. What is the most appropriate next step?
💡 EXPLANATION:
The patient has overt primary hypothyroidism with both clinical features and biochemical confirmation. Immediate treatment with levothyroxine is indicated. Further testing can be done later but should not delay therapy.
Postoperative fever and confusion in an elderly patient with an indwelling urinary catheter is most indicative of which condition?
Anonymous Quiz
10%
Atelectasis
85%
Urosepsis
5%
Surgical site infection
0%
Anastomotic leak
Maxemo EMREE 26-27
Postoperative fever and confusion in an elderly patient with an indwelling urinary catheter is most indicative of which condition?
💡 EXPLANATION:
In an elderly catheterized patient, fever with delirium strongly suggests urinary tract infection progressing to urosepsis. This corresponds to the water category in postoperative fever causes.
Maxemo EMREE 26-27
What is the primary mechanism of action of spironolactone?
💡 EXPLANATION:
Spironolactone is a potassium sparing diuretic that competitively antagonizes aldosterone receptors in the distal nephron, reducing sodium reabsorption and potassium excretion.
A 55M with resistant hypertension, carotid bruits, and peripheral artery disease has hypokalemia and elevated plasma renin activity. These findings are most consistent with which condition?
Anonymous Quiz
29%
Primary aldosteronism
48%
Renovascular hypertension
10%
Cushing syndrome
14%
Pheochromocytoma
Maxemo EMREE 26-27
A 55M with resistant hypertension, carotid bruits, and peripheral artery disease has hypokalemia and elevated plasma renin activity. These findings are most consistent with which condition?
💡 EXPLANATION:
Widespread atherosclerosis with resistant hypertension and high renin levels suggests renal artery stenosis causing renovascular hypertension. Primary aldosteronism typically suppresses renin.
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Maxemo EMREE 26-27
The underlying pathophysiology of iron deficiency anemia involves:
💡 EXPLANATION:
Iron is essential for heme synthesis. Deficiency leads to reduced hemoglobin production and microcytic hypochromic red blood cells.
A stable 30-year-old woman with pain and bleeding at 8 weeks amenorrhea has ultrasound evidence of a right adnexal mass and no intrauterine pregnancy. Beta hCG is 1200. What is the most appropriate management?
Anonymous Quiz
25%
Administer methotrexate
67%
Repeat beta hCG in 48 hours
8%
Laparoscopic salpingectomy
0%
Expectant management