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The 5th Stage of Pharmacy College -
Al-Esraa University ๐Ÿ’Š
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โ˜† ูƒูŠููŠู‡ ุญุณุงุจ ุงู„ Valance ููŠ Chapter 12.

#ุญุณุงุจ_ู‚ูŠู…ู‡_ุงู„_Valance ....... โœ…


#Chapter_12_ โ˜‘๏ธ


---โ€---------------โ˜†โ™ก๐Ÿ’Š๐Ÿ’Šโ™กโ˜†---------------



ุจู‡ุฐุง ุงู„ฺ†ุงุจุชุฑ ู†ุญุชุงุฌ ู‚ูŠู…ุฉ ุงู„ Valance
ูˆุจุณ ู„ู„ุงู…ู„ุงุญ ู„ุงู† ุจู‡ุฐุง ุงู„ฺ†ุงุจุชุฑ ู†ุญุณุจ ู„ู„ุงู…ู„ุงุญ ูู‚ุท .


ู ุงู„ูุงู„ู†ุณ ู…ุงู„ ุงู„ุงู…ู„ุงุญ ุดู†ูˆุŸ

[Valance = ุนุฏุฏ ุงู„ุงูŠูˆู†ุงุช ุงู„ู…ูˆุฌุจุฉโœ–๏ธ ุชูƒุงูุคู‡ุง]

ูŠุนู†ูŠ ู…ุซู„ุง ุนุฏู†ู‡ :-
โ–  (( CaCl2 )) ..

ฺฏู„ู†ู‡ ุนู„ู‰ ุงู„ุงูŠูˆู† ุงู„ู…ูˆุฌุจ ู†ุฑูˆุญ ุงู„ู‡ ุงู„ู„ูŠ ุฏุงุฆู…ุง ุนู„ู‰ ุงู„ุฌู‡ู‡ ุงู„ูŠุณุฑู‡ .
ู†ุฌูŠ ู‡ุณู‡ Ca ูƒู… ุงูŠูˆู† ุนุฏู†ู‡ ุงูŠูˆู† ูˆุงุญุฏ ู„ุงู† ู…ุง ูŠู…ู‡ ุฑู‚ู… ุญู„ูˆ ุฒูŠู† ุดู†ูˆ ุชูƒุงูุค ุงู„ Ca ุงู†ุชู… ุญุงูุธูŠู†ู‡ ุงู„ู„ูŠ ู‡ูˆ 2 ู ุงู„ูุงู„ู†ุณ ู…ุงู„ " CaCl2 "

ู‡ูˆ โฌ…๏ธ (( 1x2=2 ))





โ–  ู…ุซู„ุง ุนุฏู†ู‡ Kcl .

ูƒู… ุงูŠูˆู† ู…ูˆุฌุจ ู‡ู†ุงู†ู‡ ุŸ .. ุญู„ูˆ ุนุฏู†ู‡ ุงูŠูˆู† ูˆุงุญุฏ
ุดู†ูˆ ุชูƒุงูุค ู…ุงู„ ุงูŠูˆู† ุงู„ุจูˆุชุงุณูŠูˆู…
ุงู„ุชูƒุงูุค ุญุงูุธูŠู†ู‡ ู‡ูˆ 1 ู
(( 1ร—1=1 )) ..


โ–  ู…ุซู„ุง Na2Cro4 .
ุดฺฏุฏ ุนุฏุฏ ุงู„ุงูŠูˆู†ุงุช ุงู„ู…ูˆุฌุจุฉุŸ ุญู„ูˆ ุนุฏู†ู‡ 2 ุงูŠูˆู†
ุดู†ูˆ ุชูƒุงูุค ุงู„ุตูˆุฏูŠูˆู…ุŸ ุชูƒุงูุค ู…ุงู„ุชู‡ 1 ู

(( 2x1=2 ))



ูˆู†ู†ุชุจู‡ โ€ผ๏ธ ู„ู„ NH4 ู‡ุงูŠ ุงู„ 4 ู‡ูŠู‡ ู…ู† ุถู…ู† ุงู„ู…ุฑูƒุจ ู…ูˆ ุชุฑุญูˆู† ุชุถุฑุจูˆู† ุงู„ 4 ุจ ุงู„ุชูƒุงูุค ู„ุง
ุงุฐุง ุฑุงุฏ ูŠุฒูŠุฏ ุนุฏุฏ ุงู„ NH4 ู ูŠุฎู„ูŠ ุจูŠู† ู‚ูˆุณูŠู†
ูŠุนู†ูŠ ูŠุตูŠุฑ
(NH4)2

ู‡ู†ุง ู†ุถุฑุจ ุงู„2 ุจุงู„ุชูƒุงูุค

ู‡ุงูŠ ุดู„ูˆู† ู†ุญุณุจ ุงู„ูุงู„ู†ุณ ู…ุงู„ุชู‡ุง ู ู†ุถุฑุจ ุนุฏุฏ ุงู„ุงูŠูˆู†ุงุช ุงู„ู…ูˆุฌุจู‡ ุงู„ู„ูŠ ู‡ูŠู‡ 2 ู†ุถุฑุจู‡ุง ููŠ ุนุฏุฏ ุงู„ุชูƒุงูุค ู…ุงู„ ุงูŠูˆู† ุงู„ุงู…ูˆู†ูŠูˆู… ุงู„ู„ูŠ ู‡ูˆู‡ ู‡ู†ุงู†ู‡ ูŠุณุงูˆูŠ 1 ูˆูƒุงู„ุขุชูŠ :-

(( 2x1= 2 )) .




๐Ÿ”ปูˆุฐู†ูŠ ุฅุนุฏุงุฏ ุงู„ุชุฃูƒุณุฏ ู„ุจุนุถ ุงู„ุงูŠูˆู†ุงุช ุงู„ู…ูˆุฌุจุฉ ู„ุงุฒู… ุชุญูุธูˆู†ู‡ู† ู„ุฃู† ุงู„ุญู„ ูŠุนุชู…ุฏ ุนู„ูŠู‡ู†

Mg=2
Ca=2
K=1
Al=3
Na=1
NH4=1

ูˆุฅุฐุง ุงู†ุทูˆูƒู… ุงู„ุญุฏูŠุฏ ุงูˆ ุงู„ู†ุญุงุณ ู ู‡ู…ู‡ ูŠุญุฏุฏูˆู„ูƒู… ุซู†ุงุฆูŠ ุงูˆ ุซู„ุงุซูŠ
ุฅุฐุง ุซู†ุงุฆูŠ ู 2 .
ูˆุฅุฐุง ุซู„ุงุซูŠ ู 3 .
โš›ู…ู„ุฎุต ุฌุงุจุชุฑ 12๐Ÿ‘Š๐Ÿค โš›

โ˜†Electrolytes Solutionโ˜†

โœณ๏ธ ุฑูƒุฒูˆู„ูŠ ุนู„ู‰ ุฐู†ูŠ ุงู„ุงูŠูˆู†ุงุช โœณ๏ธ

Valence
________
โคต๏ธ

โ–ช๏ธNH4+=1
โ–ช๏ธMg+=2
โ–ช๏ธK+=1
โ–ช๏ธCa+=2
โ–ช๏ธNa+=1
โ–ช๏ธCL-=1


๐Ÿ‘โ€๐Ÿ—จ ุฃู†ุชุจู‡ูˆู„ูŠ ู‡ู†ุงู†ู‡ ุฐู†ูŠ ุงู„ุนู†ุงุตุฑ ุฑุงุญ ูŠู†ุฐูƒุฑู† ููŠ ุจุฏุงูŠู‡ ุงู„ู…ุฑูƒุจ ูˆุงุญู†ุง ุนู„ูŠู†ุง ู†ุฃุฎุฐ ุฃูˆู„ ุนู†ุตุฑ ู…ู† ุงู„ู…ุฑูƒุจ ูˆุงุญู†ุง ุทุจุนุง ุญุงูุถูŠู† ุงู„ฺคู„ู†ุณ ู…ุงู„ุชู‡
๐ŸŒž๐ŸคŽ....

ุŒุŒุŒุŒุฑุงุญ ู†ุทูŠูƒู… ู…ุซุงู„:


โœด๏ธ Potassium Chlorideใ€ฐKCLใ€ฐK+=1

โœด๏ธ ammonium Chlorideใ€ฐNH4CLใ€ฐNH4+=1ุŒุŒุŒุŒุŒุŒุŒุŒ

ูˆู‡ูƒุฐุง ุจู‚ูŠู‡ ุงู„ุงู…ุซู„ู‡ ๐ŸŒš


๐ŸŒŸู‡ุณู‡ ู†ุฌูŠ ู„ู„ู‚ูˆุงู†ูŠู† ุงู„ู„ูŠ ุชุฎุต ุญุณุงุจ ุงู„ู€. ู…ู„ูŠ ุงูŠูƒูˆูŠฺคู„ูŠู†ุช๐ŸŒŸ


๐ŸŒ€ Calculation of milliequivalent ๐ŸŒ€


๐ŸŒŸ ุจู‡ุฐุง ุงู„ู…ูˆุถูˆุน ุฑุงุญ ู†ุณุชุฎุฏู… 3โƒฃ ู‚ูˆุงู†ูŠู† ......


mgโœ–๏ธValence
โญ•๏ธ MEq = -------------------------
M.wt



MEqโœ–๏ธM.wt
โ– Mg/ML = ---------------------------
Valence




W (g)
๐Ÿ’  W/V % = --------------โœ–๏ธ100%
V(mL)


๐Ÿ”† ุจุงู„ู†ุณุจู‡ ู„ู‡ุฐุง ุงู„ู…ูˆุถูˆุน ูƒู„ ุงู„ุงู…ุซู„ู‡ ุงู„ู„ูŠ ุชุฌูŠ ุชุทุจูŠู‚ ู…ุจุงุดุฑ ู„ู„ู‚ุงู†ูˆู† ูู‚ุท ู†ู†ุชุจู‡ ู„ู„ูˆุญุฏุงุช ุงู„ู„ูŠ ู…ุทู„ูˆุจู‡ ุงูˆ ู…ุนุทุงู‡ ู„ุฃู† ูŠุชู„ุงุนุจ ุจุงู„ูˆุญุฏุงุช ููŠ ู…ู†ุทูˆู‚ ุงู„ุณุคุงู„ ๐Ÿฅบ๐Ÿ’œ.




๐ŸŒ€Calculations of Millimols and Micro moles๐ŸŒ€



๐ŸŒŸุนุฏู†ุง ู…ูˆุถูˆุน ุงู„ู…ู„ูŠ ู…ูˆู„ุŒุŒุŒูˆุงู„ู…ุงูŠูƒุฑูˆ ู…ูˆู„ุŒุŒุŒ ุจูŠู‡ู† ุจุณ ู‚ุงู†ูˆู†ูŠู† ุทุจู‚ูˆู†ู‡ู† ูˆุดูˆููˆุง ุงู„ู†ุชูŠุฌู‡ ๐Ÿ˜‹



M(mg)
โœณ๏ธ MMOL = -------------
M.wt



Mic (g)
๐Ÿ”… MicmoL = -------------
M.wt


๐Ÿ”† ู‡ุฐุง ุงู„ู…ูˆุถูˆุน ู‡ู…ุงุช ุชุทุจูŠู‚ ู…ุจุงุดุฑ ู„ู„ู‚ุงู†ูˆู† ุจุณ ุชู†ุชุจู‡ูˆู† ู„ู„ุชุญูˆูŠู„ุงุช ุญุณุจ ู…ุทู„ูˆุจ ุงู„ุณุคุงู„.๐Ÿฅบ๐Ÿ’œ


๐ŸŽ€๐Ÿ’–๐ŸŒธโœจ


๐ŸŒŸุชุญูˆูŠู„ุงุช ู…ู‡ู…ู‡ :-

โ™ฆ๏ธ1mol=1000mmol
โ™ฆ๏ธ1L=1000ml
โ™ฆ๏ธ1g=1000mg
โ™ฆ๏ธ1Kg=2.2lb


โš› ู†ูƒู…ู„ ู…ู„ุฎุต ุฌุงุจุชุฑ 12๐Ÿ‘Š๐Ÿค โš›



๐Ÿ”†Calculations of Milliosmoles๐Ÿ”†

๐ŸŒ€mosmol/L = ๐Ÿ‘‡๐Ÿ‘‡๐Ÿ‘‡๐Ÿ‘‡


Weight of substance (g/L)
โœ–๏ธ Number of species โœ–๏ธ 1000
------------------------------------------------------------
Molecular weight (g)



๐ŸŒŸุฑุงุญ ุงุฎุชุตุฑู„ูƒู… ู‡ู„ ุงู„ู‚ุงู†ูˆู† ุจุงู„ุฑู…ูˆุฒ ๐Ÿ˜‚๐Ÿ’”



๐ŸŒ€mosmol/L ๐Ÿ‘‡๐Ÿ‘‡๐Ÿ‘‡๐Ÿ‘‡


m(g/L)โœ–๏ธ Nu โœ–๏ธ1000
= ------------------------------------
M.wt (g)

๐ŸŒŸ ุชุนุงู„ูˆุง ุฎู„ูŠ ุงุณูˆู„ูู„ูƒู… ุนู† ุนุฏุฏ ุงู„ุงูŠูˆู†ุงุช ู‡ู†ุง ุจุงู„ุงูˆุฒู…ูˆู„ุงุฑุชูŠ ูˆุงุฑูŠุฏูƒู… ุชูุฑู‚ูˆู† ุจูŠู†ู‡ ูˆุจูŠู† ุงู„ฺคู„ู†ุณ ๐Ÿ™‰๐Ÿ’–๐Ÿค


Number of species
____________
โคต๏ธ

๐Ÿ’Ÿ Sodium chloride=NaCL=2

Na=1
CL=1
------------
1+1=2


๐Ÿ”† ุดูˆููˆุง ุญุจุงูŠุจ ู‡ู†ุง ุจุนุฏุฏ ุงู„ุงูŠูˆู†ุงุช ุฑุงุญ ู†ุฌู…ุน ุงูŠูˆู†ุงุช ู„ูƒู„ ุนู†ุตุฑ ุจุงู„ู…ุฑูƒุจ ู…ูˆ ูู‚ุท ู†ุงุฎุฐ ุงูŠูˆู†ุงุช ุฃูˆู„ ุนู†ุตุฑ ู…ุซู„ ุงู„ฺคู„ู†ุณ Valence ุŒุŒุŒุŒ๐Ÿ˜‰


๐ŸŒŸู‡ุณู‡ ู†ุฑุฌุน ู„ู„ู‚ุงู†ูˆู† ุนู„ู‰ ุงู„ุงุบู„ุจ ุฑุงุญ ูŠู†ุทูŠู†ูŠ ูƒุชู„ู‡ ุงู„ู…ุงุฏุฉ ุจุงู„ู†ุณุจู‡ ุงู„ู…ุฆูˆูŠู‡% ุงู†ูŠ ุฑุงุญ ุงุณุชุฎุฏู… ู‚ุงู†ูˆู† ุฒุบูŠุฑูˆู†ูŠ ุญุชู‰ ุงุญุตู„ ุงู„ูƒุชู„ู‡ ุจูˆุญุฏุฉ [[g/L]]


m (g)
๐ŸŸฃ W/V% = -------------
V (mL)

โ™ฆ๏ธ1L=1000mL
mLโ†’Lรท1000

๐ŸŒŸูˆู‡ูŠุฌ ุฑุงุญ ุทู„ุน ุงู„ูƒุชู„ู‡ ุจg/L
ุจุงู„ู†ุณุจู‡ ู„ู„M.wt ู„ุง ุชู‚ู„ู‚ูˆู† ุฑุงุญ ุชูƒูˆู† ู…ู† ุถู…ู† ู…ุนุทูŠุงุช ุงู„ุณุคุงู„.

โ–ช๏ธู‡ู†ุง ุณูƒุฑ ุงู„ุนู†ุจ ุนุฏุฏ ุงูŠูˆู†ุงุชู‡=1 ุญูุธ๐ŸŒš

โ™ฆ๏ธdextrose =1


โ™ฃ๏ธ ูˆู‡ูŠุฌ ู†ูƒูˆู† ู‡ูƒุฑู†ุง ุฌุงุจุชุฑ 12 ๐Ÿ’ช
ู„ุง ุชู†ุณูˆู†ูŠ ูˆูˆุงู„ุฏูŠ ู…ู† ุงู„ุฏุนุงุก ุงุฎุชูƒู… โค๏ธ

PHโ€ขFatima Fahd๐Ÿ‘ฉโ€โš•๐Ÿฉบ
Forwarded from ูƒู„ูŠุฉ ุงู„ุตูŠุฏู„ุฉ ุงุฎุชุจุงุฑุงุช ุณุฑูŠุนุฉ + ู…ุนู„ูˆู…ุงุช ุทุจูŠุฉ (Ahmed habib)
The volume of alcohol 95% v/v needed to produce 1.90 L of 50% v/v.
Anonymous Quiz
15%
100 mL
6%
4200 ml
8%
420 ml
71%
1000 ml
Forwarded from ูƒู„ูŠุฉ ุงู„ุตูŠุฏู„ุฉ ุงุฎุชุจุงุฑุงุช ุณุฑูŠุนุฉ + ู…ุนู„ูˆู…ุงุช ุทุจูŠุฉ (Ahmed habib)
How many grams of sodium chloride should be used in compounding the following prescription
Rx Ingredient X 0.5 g
Sodium Chloride q.s ad 50 mL Purified Water Make isoton. sol Sig. Eye drops E v = 0.26
Anonymous Quiz
66%
0.32 g
9%
0.45 g
13%
0.50
12%
0.13 g
Forwarded from ุณุฑูŠุฑูŠุฉ
Zinc sulfate is a 2-ion electrolyte, dissociating 40% in a certain concentration. Calculate its dissociation (i factor.
Anonymous Quiz
13%
None
26%
1.8
50%
1.4
11%
2. 6
Forwarded from ูƒู„ูŠุฉ ุงู„ุตูŠุฏู„ุฉ ุงุฎุชุจุงุฑุงุช ุณุฑูŠุนุฉ + ู…ุนู„ูˆู…ุงุช ุทุจูŠุฉ (Ahmed habib)
How many grams of a 1:10 trituration are required to obtain 25 mg of drug?
Anonymous Quiz
60%
0.25 g
12%
0.20g
28%
0.025 g
Forwarded from ูƒู„ูŠุฉ ุงู„ุตูŠุฏู„ุฉ ุงุฎุชุจุงุฑุงุช ุณุฑูŠุนุฉ + ู…ุนู„ูˆู…ุงุช ุทุจูŠุฉ (Ahmed habib)
How many milliliters of a syrup containing 85% w/v of sucrose should be mixed with 150 mL of a syrup containing 60% w/v of sucrose to make a syrup cotaining 80% w/v of sucrose?
Anonymous Quiz
12%
3000 mL
16%
6000ml
65%
600ml
7%
610ml
Forwarded from ูƒู„ูŠุฉ ุงู„ุตูŠุฏู„ุฉ ุงุฎุชุจุงุฑุงุช ุณุฑูŠุนุฉ + ู…ุนู„ูˆู…ุงุช ุทุจูŠุฉ (Ahmed habib)
Calculate the sodium chloride equivalent for timolol maleate which dissociates into two ions and has a molecular weight of 432 Timolol maleate,i factor =1.8
Anonymous Quiz
12%
0.014
76%
0.14
12%
0.15
Forwarded from ุณุฑูŠุฑูŠุฉ
How many milliliters of a 1% w/v epinephrine injection must be used to prepare 20 ml of an injection containing 1:200000 w/v epinephrine?
Anonymous Quiz
59%
0.01 ml
10%
1 ml
22%
0.001
10%
0.1 ml
Forwarded from ุณุฑูŠุฑูŠุฉ
Zinc sulfate is a 2-ion electrolyte, dissociating 40% in a certain concentration. Calculate its dissociation (i factor.
Anonymous Quiz
13%
None
26%
1.8
50%
1.4
11%
2. 6
Forwarded from ุณุฑูŠุฑูŠุฉ
Zinc chloride is a 4-ion electrolyte, dissociating 80% in a certain concentration. Calculate its dissociation (i) factor.
Anonymous Quiz
16%
None
16%
2.6
67%
3.4
Forwarded from ุณุฑูŠุฑูŠุฉ
Zinc chloride is a 1-ion electrolyte, dissociating 80% in a certain concentration. Calculate its dissociation (i) factor.
Anonymous Quiz
28%
1.8
8%
2.6
14%
1.1
50%
None
Forwarded from ูƒู„ูŠุฉ ุงู„ุตูŠุฏู„ุฉ ุงุฎุชุจุงุฑุงุช ุณุฑูŠุนุฉ + ู…ุนู„ูˆู…ุงุช ุทุจูŠุฉ (Ahmed habib)
How many grams of a 1:10 trituration are required to obtain 25 mg of drug?
Anonymous Quiz
60%
0.25 g
12%
0.20g
28%
0.025 g
Forwarded from ูƒู„ูŠุฉ ุงู„ุตูŠุฏู„ุฉ ุงุฎุชุจุงุฑุงุช ุณุฑูŠุนุฉ + ู…ุนู„ูˆู…ุงุช ุทุจูŠุฉ (Ahmed habib)
How many milliliters of a syrup containing 85% w/v of sucrose should be mixed with 150 mL of a syrup containing 60% w/v of sucrose to make a syrup cotaining 80% w/v of sucrose?
Anonymous Quiz
12%
3000 mL
16%
6000ml
65%
600ml
7%
610ml
Forwarded from ูƒู„ูŠุฉ ุงู„ุตูŠุฏู„ุฉ ุงุฎุชุจุงุฑุงุช ุณุฑูŠุนุฉ + ู…ุนู„ูˆู…ุงุช ุทุจูŠุฉ (Ahmed habib)
Calculate the sodium chloride equivalent for timolol maleate which dissociates into two ions and has a molecular weight of 432 Timolol maleate,i factor =1.8
Anonymous Quiz
12%
0.014
76%
0.14
12%
0.15
Forwarded from ุญูŠุฏุฑ.
Q2/ If 1 gallon of a 30% w/v solution is to be evaporated so that the solution will have a strength of 50% w/v, what will be its volume in milliliters?
Forwarded from ุญูŠุฏุฑ.
Q How many grams of 2.5% hydrocortisone cream should be mixed with 360 g of 0.25% cream to make a 1% hydrocortisone cream?๐Ÿ™‚
Forwarded from ุญูŠุฏุฑ.
many grams of white petrolatum should be mixed with 250 g of 5% and 750 g of 15% zinc oxide ointments to prepare a 10% ointment?
Forwarded from ูƒู„ูŠุฉ ุงู„ุตูŠุฏู„ุฉ ุงุฎุชุจุงุฑุงุช ุณุฑูŠุนุฉ + ู…ุนู„ูˆู…ุงุช ุทุจูŠุฉ (Ahmed habib)
How many milliliters of 37% w/w hydrochloric acid having a specific gravity of 1.20 are required to make 1000 mL of diluted hydrochloric acid 10% w/v?
Anonymous Quiz
17%
270 mL
75%
225 ml
8%
220 ml
The formula for asports rubcream
is given in the literature as follows
Methyl salicylate Menthol 15 ml 10g
1g Eucalyputus oil Hydrphilic ointment .qs ad 100gIf the specific gravity of methyl salicylate is 1.18.
How many grams of hydrophilic ointment would be needed to prepare adozen 30-g tubes of ointment .