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Carcinoma of the prostate

Which of the following statements are true in carcinoma of the prostate?except

A It is the most common cancer in men over the age of 65 years.

B In the younger age group who develop prostate cancer, 10%–15% have a positive family history.

C A patient who has had a prostatectomy for BPH can develop prostate cancer. D Carcinoma mostly originates in the peripheral zone of the prostate.

E Prostate-specific antigen (PSA) is an extremely reliable method of screening
9. The following statements are true except:

A The histological type is an adenocarcinoma.

B Gleason scoring system is based on the degree of glandular differentiation.

C The Gleason score correlates well with spread and prognosis.

D Prostate is the most common site of origin for skeletal metastasis.

E Skeletal metastases from prostate cancer are mostly osteolytic.
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On rectal examination, which of the following features does not suggest carcinoma?

A Nodules within the prostate.

B Obliteration of the median sulcus.

C Irregular stony hard induration.

D Mobile rectal mucosa over the prostate.

E Extension of a hard nodule beyond the capsule into the bladder base.
11. In the assessment of prostate cancer which of the following investigations are necessary?except

A Transrectal ultrasound-guided biopsy (TRUS)
B Cross-sectional MRI
C Bone scan
D General blood tests, PSA and liver function tests
E IVU
12. Regarding treatment, the following statements are true except:

A Radical prostatectomy is only suitable for T1 and T2 disease (early cancer).

B Radical external-beam radiotherapy is an alternative to radical prostatectomy. C T3 patients are treated by surgery, radical radiotherapy, or androgen ablation.

D Incidentally diagnosed disease is treated by radical prostatectomy.

E The incidence of severe stress incontinence after radical prostatectomy is about 2%.
1. Which of the following statements are true?except

A The verumontanum is situated in the membranous urethra.

B The membranous urethra is the primary location of continence.

C The anterior urethra is composed of a bulbar and a penile part.

D The posterior urethra comprises of preprostatic, prostatic and membranous segments.

E The major portion of the female urethra is lined by stratified squamous epithelium.