Study room 808
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7. The following statements are true except:

A α-adrenergic blocking agents inhibit the contraction of prostatic smooth muscle. B 5α-reductase inhibitors inhibit the conversion of testosterone to DHT.

C Drug therapy results in 20% improvement in symptom scores.

D Transurethral resection of the prostate (TURP) results in 75% improvement in the symptom scores.

E Retrograde ejaculation occurs in all patients after TURP.
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Carcinoma of the prostate

Which of the following statements are true in carcinoma of the prostate?except

A It is the most common cancer in men over the age of 65 years.

B In the younger age group who develop prostate cancer, 10%–15% have a positive family history.

C A patient who has had a prostatectomy for BPH can develop prostate cancer. D Carcinoma mostly originates in the peripheral zone of the prostate.

E Prostate-specific antigen (PSA) is an extremely reliable method of screening
9. The following statements are true except:

A The histological type is an adenocarcinoma.

B Gleason scoring system is based on the degree of glandular differentiation.

C The Gleason score correlates well with spread and prognosis.

D Prostate is the most common site of origin for skeletal metastasis.

E Skeletal metastases from prostate cancer are mostly osteolytic.
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On rectal examination, which of the following features does not suggest carcinoma?

A Nodules within the prostate.

B Obliteration of the median sulcus.

C Irregular stony hard induration.

D Mobile rectal mucosa over the prostate.

E Extension of a hard nodule beyond the capsule into the bladder base.