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13. In the treatment of bladder cancers, which of the following statements are true?except

A Non-muscle invasive (superficial) tumours are treated by endoscopic resection and a single dose of mitomycin instillation.

B Grade 3 superficial disease is best managed by BCG immunotherapy.

C External beam radiotherapy should be the first-line treatment in muscleinvasive disease.

D When the cancer has invaded muscle (pT2 and pT3) radical cystectomy and lymphadenectomy is the treatment of choice.

E Neoadjuvant cisplatin-based chemotherapy improves survival in muscle-invasive tumours.
1. The following statements are true except:

A The prostate is anatomically divided into a peripheral zone, a central zone and a transitional zone.

B The glands of the peripheral zone are lined by transitional epithelium.

C Benign prostatic hypertrophy occurs in the transitional zone.

D Most carcinomas arise in the peripheral zone.

E Denonvilliers’ fascia separates the prostate from the rectum.
Which of the following statements are true?except

A Luteinising hormone (LH) from the anterior pituitary controls the secretion of testosterone.

B Leydig cells from the testes secrete 90% of the testosterone.

C The enzyme 5α-reductase type II is found in high concentration in the prostate.

D 5α-reductase converts testosterone into 1.5-dihydrotestosterone (DHT).

E Prostate-specific antigen (PSA) is both specific and sensitive in the diagnosis of prostate cancer.
4. In urodynamic studies, which of the following statements are true?except

A A voided volume >200 mL with a peak flow rate >15 mL/s is normal.

B A voiding pressure of <60 cm H2 O is normal.

C Increase in voiding pressures with a low flow rate is diagnostic of BOO.

D In patients with a residual volume of 250 mL or more, bilateral hydronephrosis will result.

E Urodynamically proven BOO only occurs from BPH.
Management of BPH causing BOO

6. Which of the following statements are true?except

A All patients with acute retention ultimately require prostatectomy.

B Chronic retention accounts for 15% of prostatectomies.

C Severe symptoms account for 60% of prostatectomies.

D Drug therapy is with α-blockers and/or 5α-reductase inhibitor.

E A low maximum flow rate of <10 mL/s and a residual volume of 100–250 mL are indications for surgery.
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Management of BPH causing BOO

6. Which of the following statements are true?except

A All patients with acute retention ultimately require prostatectomy.

B Chronic retention accounts for 15% of prostatectomies.

C Severe symptoms account for 60% of prostatectomies.

D Drug therapy is with α-blockers and/or 5α-reductase inhibitor.

E A low maximum flow rate of <10 mL/s and a residual volume of 100–250 mL are indications for surgery.
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