OPIOIDS ‼️
• “Morphine: miosis + constipation + retention”NOT urination
• “Methadone = long acting withdrawal control”✔️ addiction treatment
• “Meperidine = seizures” ⚠️ anticholinergic effect
• Naloxone does NOT treat withdrawal
• Morphine ❌ NOT for head injury ✔️ Crosses placenta
• Opioids ❌ NOT anti-inflammatory
• Buprenorphine ❌ not easily reversed ✔️ sublingual
• Codeine ❌ not addiction-free
Tramadol = Inhibits 5-HT & NE reuptake
(cancer patients) → give laxative
• “Morphine: miosis + constipation + retention”NOT urination
• “Methadone = long acting withdrawal control”✔️ addiction treatment
• “Meperidine = seizures” ⚠️ anticholinergic effect
• Naloxone does NOT treat withdrawal
• Morphine ❌ NOT for head injury ✔️ Crosses placenta
• Opioids ❌ NOT anti-inflammatory
• Buprenorphine ❌ not easily reversed ✔️ sublingual
• Codeine ❌ not addiction-free
Tramadol = Inhibits 5-HT & NE reuptake
(cancer patients) → give laxative
❤7
Local Anesthetics ✅
Non-ionized form → crosses membrane ✔️
• Alkaline pH → ↑ effect ✔️
Bupivacaine = heart danger ⛔️
Prilocaine = metHb
Benzocaine = topical only
Amides = ❗ More systemic toxicity
Procaine = NOT used topically ❗
Articaine = both amide + ester bond ❗
Procaine = allergy
Non-ionized form → crosses membrane ✔️
• Alkaline pH → ↑ effect ✔️
Bupivacaine = heart danger ⛔️
Prilocaine = metHb
Benzocaine = topical only
Amides = ❗ More systemic toxicity
Procaine = NOT used topically ❗
Articaine = both amide + ester bond ❗
Procaine = allergy
❤10