NAD+
https://collabs.shop/efhzdm

Use code PRIMALSAM for 10% off your order!

*Research peptides are for research use only, and not specified for human, animal, or in-vivo use only.

TFW your morning run does the opposite
*Especially with cortisol issues

🏃‍♀️ So let's talk about something that might be blowing your mind right now... that morning run you're KILLING yourself to wake up for? It might actually be working AGAINST your weight loss goals, especially if you have cortisol issues or autoimmunity.

Here's what's actually happening: 🤯

→ When you have autoimmune disease or adrenal issues, intense cardio can spike your cortisol (that pesky stress hormone) even HIGHER than it already is.

→ And what does cortisol loves to do? Store fat, especially around your middle, and mess with your hormone and thyroid function.

→ Then you're exhausted but wired, craving sugar by 3pm, can't sleep even though you're tired, and the scale won't budge despite your perfect diet.

🌤 What if instead, you could:

• Wake up feeling ACTUALLY rested (not just caffeine-ready)

• Exercise in a way that SUPPORTS your hormones instead of draining them

• Watch inflammation melt away (goodbye puffy face!)

• Feel energized ALL day (not just the first hour after coffee)

I'm not saying throw away your running shoes! I'm saying we need to work WITH your body, not against it (ie, those are your lovely walking shoes now, honey). 👟👟

Want to know exactly how I restructured my workout routine to support my own fatigued adrenals + Hashimoto's?

📰💖 I've got all the details in this archive blog post where I break down the science and what can work instead:

https://tinyurl.com/46ds852m

Your body is trying to recover - let's stop fighting it and start working with it.

*Not medical advice.

Cagrilintide: An Exciting New Approach to Weight Management
Recent research on cagrilintide is showing promising results for weight management through a different mechanism than GLP-1 agonists. Here's what you should know:

What is Cagrilintide?
Cagrilintide is a long-acting amylin analog that mimics the hormone amylin, which works alongside insulin to regulate glucose metabolism and appetite. Unlike GLP-1 agonists (semaglutide, tirzepatide), cagrilintide targets the amylin receptor pathway.

Key Benefits:
Reduces hunger and food cravings
Promotes satiety (feeling of fullness)
Slows gastric emptying
Can complement GLP-1 therapy through different mechanism

How It Differs from GLP-1 Medications:
While GLP-1s like Ozempic and Wegovy work by targeting GLP-1 receptors to reduce appetite and slow digestion, cagrilintide works through the amylin pathway. The key difference:
GLP-1s: Impact insulin secretion and blood glucose directly
Cagrilintide: Primarily focuses on appetite regulation without direct blood glucose effects

Clinical Trial Results:
Cagrilintide Alone: Phase 2 trials showed dose-dependent weight loss of up to 10.8% at highest doses over 26 weeks
Combined with Semaglutide: The combination therapy showed enhanced weight loss compared to either medication alone
REDEFINE (rx brand name of Cagri + Sema combined) Phase 3 Trial: Combining weekly cagrilintide with semaglutide demonstrated significantly greater weight reduction than semaglutide alone

Common Side Effects:
Fatigue (most commonly reported)
Nausea
Injection site reactions
Constipation
Reduced appetite (intended effect)

Microdosing Approach to Minimize Side Effects:
Subjects report success with peptides with a microdosing strategy:
Start with very small doses (much lower than standard)
Gradually increase dose over extended period *if tolerated and necessary
Allow body to adjust more slowly to reduce fatigue and GI symptoms
Ensure adequate hydration and electrolyte balance

This represents a significant advance in weight management medications, offering a new pathway that can work alone or synergistically with existing GLP-1 therapies.

CAGRI is ON SALE! Save $30/vial.

Eligible for further multi-vial pricing at this discount, and stackable with my discount code PRIMALSAM

https://polarispeptides.com/product/cagrilintide-5mg/

*Research peptides are for research use only, and not specified for human, animal, or in-vivo use only.

Hi tribe! 👋 Just a reminder that posting outside sources of research materials goes against channel guidelines.

I keep an eye out for these posts so there is no circulation of potentially harmful products, as well as to protect the time I put into creating content and research for our channel.

These types of posts will be deleted to protect the channel, and the user will be removed.

Thanks so much for choosing to learn with me about peptides, and please let me know if you have any questions at all!

xx
Sam

Ever been so tired of fighting your own body that you just wave the white flag? 🏳️

There I was, staring at yet another unflattering photo (you know the kind), wondering if "accepting" my metabolic malfunction fate was really the answer.

Spoiler alert: it wasn't. My body was SCREAMING for help.

My energy? Nonexistent.
My weight? Stubborn as that stain on your favorite shirt.
My libido? We were no longer on speaking terms.
My mood? I avoided my family so I didn’t snap over small crap.
My confidence? A sad and wrinkly deflated birthday balloon.

I decided "acceptance" wasn't going to cut it anymore. I couldn't live like this anymore.

Here's exactly how I flipped the script:

I completely revolutionized my approach to hormones and inflammation. Instead of just "dealing with it," I got strategic with ancestral wisdom plus modern science (because why choose just one?).

The transformation wasn't just about the number on the scale (though hello, jeans that fit again! 👖). It was waking up ACTUALLY feeling rested. Having energy past 2pm. Feeling again like that woman who used to laugh, feel sexy, and not want to bite someone's head off over tiny inconveniences.

Which sounds more like you?
-"I've tried everything and nothing works"
-"My doctor says my labs are normal but I feel TERRIBLE"
-"I'm so tired of being tired"
-“Specialists gave up on me.”

If you're nodding yes, I've got something for you: a method to reclaim your energy, waistlines, and zest for life, all by using my uncensored approaches to hormonal health.

Want the unfiltered protocol? Stay tuned for my next post for the simplified version of the steps I added the last two years that made ALL the difference.

P.S. Remember that unflattering jeans photo I mentioned? It's now my "before" pic. What would YOUR "before" pic be?

🔥 THE UNCENSORED PROTOCOL: What ACTUALLY Worked for My Subject When Nothing Else Did 🔥

Welcome to the no-BS zone! Here's the FULL protocol that mainstream medicine doesn't want you talking about:
(Psst: Stay tuned for later this week where I’ll be dropping a downloadable checklist to help you implement this above protocol in your own research! )

1️⃣ Dual GLP-1 Support
• My research subject used low-dose, bi-weekly GLP-1 (two different formulations, Reta and Tirz) with INCREDIBLE results.
• Not just for weight - for inflammation markers too!
👉 Download my Free Quick Start Guide: Peptides for Weight Loss HERE:
https://t.me/primalpeps/484

2️⃣ Mitochondrial Resurrection
• Modern research subjects’ cellular powerhouses are DYING. Here's how to put that into reverse:
• MOTS-c peptide support
• Microdosing cycle strategy 3x / year makes this affordable and gentle - get my free Microdosing Magic Guide here: https://www.dropbox.com/scl/fo/e2zv3bex32q3madg95ab1/AJ8Zm4t_RV-CFD5HiCvQEec?rlkey=h8xe8l9al3r78s6rr3b4a7l1d&st=udki53rr&dl=0
• Learn more about MOTS-c here (research use only) and save on your first order of research materials: https://polarispeptides.com/product/mots-c-10mg/nebula/primalsam/ - use code PRIMALSAM to save 10%
• nnEMF awareness and mitigation steps (game changer!)
• Turn off wifi at night
• Ethernet cable
• Phone and electronics out of bedroom
• Red Light Therapy - 15 min daily transformed my energy
👉 My favorite RLT mat is the flexible Thera Tri-Lite - use code PRIMALSAM to save 10%
https://therasage.com/products/single-red-light-panel?rfsn=7881394.971241&variant=31128343248980&utm_source=refersion&utm_medium=affiliate&utm_campaign=7881394.971241

3️⃣ True Hydration (not just "drinking water")
• Standard water = basically useless without minerals and with fluoride added
• Added specific minerals to filtered water based on HTMA testing
• My personal mineral cocktail was extra sodium, potassium, molybdenum.
• Get checked here (not affiliated, just in love with their service and pricing): https://www.optimalhealthnetwork.com/Hair-Tissue-Mineral-Analysis-HTMA-p/ohchtma.htm
• My fave general tonic for remineralizing water: Concentrace Trace Mineral Drops - Glass Bottle - by Trace Minerals Research.
• Access my dispensary and get 25% off ongoing: https://us.fullscript.com/welcome/steague

4️⃣ Hormone Optimization (the REAL secret)
• THIS was the true turning point! Nothing compares to:
• INJECTABLE Testosterone (creams, pellets, troches just don't cut it as well)
• Bioidentical estradiol + progesterone in perfect balance Result: Complete body recomposition, energy surge, libido BACK
• Paloma can help with HRT (thyroid, estrogen, progesterone) except Testosterone https://app.palomahealth.com/referral/PRIMALSAM
• Regenics may be able to help qualifying women with Testosterone https://regenics.com/?ref=8252

5️⃣ Strategic Protein Protocol
• Less than fitness influencers recommend.
• More than USDA says you need.
• Focus on ANIMAL protein sources for bioavailability, supplementing with non-soy, non-legume sources as needed (ie, nuts and seeds)
👉 FREE Quick Protein Bites Guide: https://t.me/primalpeps/60
👉 My family gets our meat from Butcher Box (MRNA-free promise, antibiotic-free, hormone-free) - use my link for FREE protein for a year (I will earn a small commission if you purchase through my affiliate link): https://butcherbox.pxf.io/N9QaMP

6️⃣ Circadian Rhythm Repair
• The foundation everything else builds on:
• Morning sunlight exposure (non-negotiable!)
• Meal timing aligned with cortisol rhythm
• Evening red light + blue light blocking
👉 FREE QUANTUM SUPPORT GUIDE: https://www.dropbox.com/scl/fo/fqe0hqdesoxpnpebfqb5e/AJTbHlolAmsQUcM5JgSbRq8?rlkey=ehz02bdxggbnhe0ncb2pedujc&st=lguwoq8a&dl=0
👉 These high quality Bon Charge blue blockers clip onto any glasses: https://boncharge.com/products/clip-on-blue-light-blocking-glasses?rfsn=8520396.5606126 + use PRIMALSAM for 15% off

Your Body Isn't Broken - It's Just Speaking a Language No One Taught You to Understand

How deep have you fallen into the "why am I still not feeling better?" spiral despite trying ALL. THE. THINGS?

I used to be that person with 37 different supplements cluttering my counter but no actual PLAN. Sound familiar? 😏

My targeted supplement plans aren't random collections - they're precisely formulated to address specific issues with FEWER supplements than you're probably taking now.

Plus, each plan comes with a FREE mini module!

Choose your own adventure:

🦋 Thyroid Support + free Quantum Thyroid Bundle (thyroid optimization that doesn't require a medical degree) 🔗 tinyurl.com/mrydwz79

⚖️ GLP-1 Support + Weight Loss Quick Start Bundle (for sustainable results that don't involve crying into kale leaves) 🔗 tinyurl.com/yuh2cxws

🦠 Standard Viral Protocol + free Viral Infections Module - One of the most common underlying conditions making your progress stuck is reactivated EBV and over 90% of people are affected! 🔗 tinyurl.com/3vmeys6c

Imagine waking up and actually WANTING to bound out of bed instead of hitting snooze 6 times. Picture opening your closet and feeling excited about what to wear instead of dreading how things will fit. Think about having the mental clarity to be fully present instead of nodding along while your brain feels like it's swimming through fog. That's not a fantasy - that's what happens when you finally address what's REALLY going on!

This isn't just about supplements – it's about reclaiming the version of you that's been hiding under those symptoms.

⏰ Take 25% my full dispensary: us.fullscript.com/welcome/steague

Happy Monday, Tribe! Just popping in to let you know that the "THE UNCENSORED WEIGHT LOSS PROTOCOL: STEP-BY-STEP IMPLEMENTATION GUIDE AND JOURNAL" is still in the works.

I decided to upgrade it into a journal and add resources for you so publication has been delayed slightly.

I felt it needed to be more robust and helpful for you to use, so please pardon the brief delay as I put some more bells and whistles on it this week! 😉

Reta-Cagri: Hunter Williams’ Personal Dosing Protocol

“Through meticulous experimentation on myself, I’ve refined the ideal ratios for combining retatrutide and cagrilintide, calibrated precisely to your hunger-control needs without causing nausea or excessive fullness:

4:1 Ratio (Retatrutide : Cagrilintide) Perfect for subtle, extra hunger control. If retatrutide alone nearly covers your hunger but leaves slight cravings, this ratio is ideal.
My Current Protocol: I personally love the 4:1 ratio because it perfectly manages hunger on non-training fasting days, while still letting me comfortably eat and fuel on heavy lifting days. Zero nausea, perfect hunger balance.

2:1 Ratio (Retatrutide : Cagrilintide) Delivers significantly stronger hunger suppression. If you’ve tried retatrutide alone but still struggle with consistent cravings or emotional snacking, this ratio hits the sweet spot—powerful but manageable.

1:1 Ratio (Retatrutide : Cagrilintide) This is your “big gun” for extreme cases—serious hunger struggles, compulsive eating, or stubborn food addictions. Cravings nearly vanish, and hunger signals become minimal.
Important Note: This ratio can increase nausea or discomfort, so use responsibly, and maintain proper electrolyte and protein intake.

Right now, the 4:1 ratio is my ideal choice.

It provides perfect hunger management, keeping my training and fasting routine effortless, and it’s been an absolute game changer for achieving and maintaining peak body composition.”

-Hunter Williams

Let's chat about the easiest wellness switch I've made that's had such a positive impact! 💙

The wellness hack that easily saves me $1500 a year, helps my energy levels, AND supports my thyroid.

Hint: It's not a supplement, it's not a diet change, and you use it every single day without thinking about it: tinyurl.com/4ed4bamr

After years of trying different approaches for my thyroid health, sometimes the simplest solutions are hiding in plain sight! Who knew that changing what I drink would make such a difference?

Being mindful about water quality is just as important as the food we carefully choose. Plus, I found an easy, no-installation-needed solution that looks lovely in my kitchen.

I'm sharing all the details about how I filter my water (including what minerals I add back in for optimal balance) on the blog today. It's been such a game-changer for the whole fam!

🚰 The hormone solution that’s in your kitchen sink: tinyurl.com/4ed4bamr

Would love to know - have you thought about your water quality lately? What questions do you have?

*Not medical advice.

JUST RELEASED: The Uncensored Weight Loss Protocol 🔥

How I FINALLY broke through my stubborn weight plateau when nothing else worked (even after addressing thyroid issues and eating "clean")...

This isn't your typical "eat less, move more" advice. I'm sharing the exact 6-part system that transformed my metabolism when it seemed permanently broken after gallbladder removal:

✅ The hormone optimization strategy that mainstream doctors aren't discussing
✅ Why small doses of two specific GLP-1 formulations worked better than one
✅ The mitochondrial resurrection protocol that fired up my cellular energy
✅ My TRUE hydration formula (hint: drinking plain water isn't enough)
✅ The protein strategy that balances leptin and cortisol naturally
✅ The precise circadian reset that makes everything else work

Plus a DAY-BY-DAY implementation checklist so you know exactly what to do and when (after discussing this with your doctor, of course)!

👉 DOWNLOAD IT HERE: https://www.dropbox.com/scl/fo/7woasifj9omuf3a6yh38a/AAJxbSdLa1uFaoMncCdJhuQ?rlkey=k3n8z9qrrgmd0togcwpaa1m2n&st=fu2kkjo2&dl=0

Thank you for your patience as I worked to make this guide even more comprehensive and actionable! If it helps even one person reclaim their health the way it helped me, it was worth every minute.

XX,
Sam

My girlfriend sent me an ad for this supplement to review, & I thought I'd share what I found with y’all who are navigating health challenges similar to mine.

When you're dealing with autoimmunity or chronic health issues 🙋‍♀️, what looks "healthy" on the surface can sometimes work against you.

Looking at this blend with 60 ingredients (holy moly), here's what concerned me (color coded):

💜 Gut Disruption: Ingredients like pectin, plant-based iron, & supplemental prebiotics can irritate an already sensitive digestive system. If you've got bloating, irregular BMs, or food sensitivities, these additives might make things worse rather than better.

💛 High Oxalates: These plant ingredients are low in bioavailable nutrients AND high in oxalates, which can bind to minerals in your GI & prevent proper absorption of the very nutrients you're trying to get...leading to potential nutrient deficiencies.

🧡 Immune Stimulants: For those with autoimmunity, certain "superfoods" can actually increase cytokine production and may trigger flares. That sudden joint pain, brain fog, or fatigue after starting a new supplement? This could be why.

💚 Untailored Adaptogens: Adaptogens are powerful, but timing matters! Taking them at the wrong time relative to your unique cortisol pattern can disrupt your adrenal glands & energy regulation instead of supporting these.

🤍 Quality Concerns: Many of these blends use lower-quality forms of ingredients while charging premium prices. Citric acid is one of them, which is typically grown in GMO corn mold. Yuk.

When I was at my lowest health point, simplifying my nutrition is a factor that made all the difference. Sometimes less truly is more.

I crafted an affordable *General Nutrient & Anti-Inflammatory Plan* for gentle gut support with natural anti-inflammatory & immune-supportive benefits. It contains ancestral-focused vitamins that don't over-stimulate the immune system.

Save 25% inside my dispensary + free shipping on orders $50+: tinyurl.com/238ws72r

Hey Tribe! Popping in to let you know that I updated the font size inside your Uncensored Weight Loss Protocol guide so that it is more mobile friendly. 😊

You can re-download it here: https://www.dropbox.com/scl/fo/7woasifj9omuf3a6yh38a/AAJxbSdLa1uFaoMncCdJhuQ?rlkey=k3n8z9qrrgmd0togcwpaa1m2n&st=fu2kkjo2&dl=0

Ever tried something new for your health only to have your body respond with "umm...that's gonna be a NO from me"? 😅

Last month I switched antidepressants hoping for better OCD management. Instead? I gained 6 pounds (eating the SAME foods!), my OCD went into overdrive making me feel like Melvin from "As Good As It Gets" (IYKYK), and my libido that had FINALLY improved with TRT? Completely vanished.

But here's the thing – this "fail" was actually a WIN in disguise.

Why? Because now I KNOW what doesn't work for MY unique body. I grieved briefly, then called my psychiatrist: "Bruh, this Zoloft situation is NOT it. Back to Lexapro we go!"

The good news is that I'm seeing these all of these issues starting to reverse just 1 week into switching back to the rx that was working before! :-)

Your body is constantly communicating with you. Those "failures" are actually valuable data points showing you what IS working by contrast.

After 10+ years of biohacking, I've learned that keeping detailed journals, taking breaks between experiments, and testing one thing at a time (with professional guidance) are absolute game-changers.

You're not failing – you're gathering intel for your personal health blueprint. That frustrating reaction? It's your body's way of steering you toward what truly works.

What health "fail" ended up teaching you something valuable? Drop it below! 👇