Which of the following is CORRECT for Murexide test?
Anonymous Quiz
73%
A. Caffeine + Hcl + KCI3
13%
B.Caffeine + H2SO4 + KCI3
9%
C.Caffeine + HNO3 + Br2
4%
D.Caffine + H2 + N2
Nuxvomica and areca extracted from?
Anonymous Quiz
11%
A.Roots
2%
B.Bark
84%
C.Seed
3%
D.Flowering buds
Alkaloids found in fungi is
Anonymous Quiz
1%
A.Cinchona
0%
B.Ipecac
55%
C.Ergot
5%
D.Citrina
39%
E.Both c&d
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The name of the alkaloids are obtained
from the generic name of the plant yielding them such as
from the generic name of the plant yielding them such as
Anonymous Quiz
18%
A. (cocaine, belladonnine)
73%
B.hydrastine, atropine
6%
C.ergotamine , atropine
3%
D.pelletierine
Some alkaloids can be extremely harmful to mammals, which is the case of the
intoxication.
steroidal alkaloid cyclopamine in lambs, identified as the compound
intoxication.
steroidal alkaloid cyclopamine in lambs, identified as the compound
Anonymous Quiz
67%
A.in Veratrum californicum (Liliaceae) responsible for teratogen effects
20%
B.in Veratrum californicum (Leguminsae) responsible for teratogen effects
4%
C.in Veratrum californicum (Rubiaceae) responsible for teratogen effects
9%
None of them
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DOC-20230221-WA0012..pdf
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المحاضرة الثانية عقاقير
Pyridine –piperidine-pyrolidine alkaloids
Pyridine –piperidine-pyrolidine alkaloids
❤4
Biosynthesis of pyridine - pyrolidine alkaloids
-من اسمه يعني يحوي على كل من
-pyridine
حلقة سداسية غير مشبعه
-pyrolidine
حلقة خماسية
الجزء الاساسي هو ornithine
اما جزء المساعد هو metionine نحصل منه ch3
⛔️ ينتج النه من اندماج كل من
Ornithine (حامض اميني)
+
Nicotine
في الtobacco
🔅هذه الاندماج يكون symmetric متماثل
⛔️ شنو الوسيط الرأيسي بهل انتاج؟
N-methyl pyrolidinium ion
حيث يحدث عملية electrophilic substitution في الكاربونه رقم 3 من حلقة الpyridine للNicotinic acid
-من اسمه يعني يحوي على كل من
-pyridine
حلقة سداسية غير مشبعه
-pyrolidine
حلقة خماسية
الجزء الاساسي هو ornithine
اما جزء المساعد هو metionine نحصل منه ch3
⛔️ ينتج النه من اندماج كل من
Ornithine (حامض اميني)
+
Nicotine
في الtobacco
🔅هذه الاندماج يكون symmetric متماثل
⛔️ شنو الوسيط الرأيسي بهل انتاج؟
N-methyl pyrolidinium ion
حيث يحدث عملية electrophilic substitution في الكاربونه رقم 3 من حلقة الpyridine للNicotinic acid
❤9
The important alkaloid in indian tobacco is
Anonymous Quiz
4%
A) morphine
56%
B)lobeline
41%
C)nicotine
0%
D)ephidrine
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Derivatives of piperidine
Anonymous Quiz
69%
A)lobeline
7%
B)ornithine
1%
C) asparatine
23%
D) all above
The family of lobelia inflate is
Anonymous Quiz
6%
A. Solanaceae
88%
B. Lobeliaceae
1%
C. Asteraceae
5%
D. Umbellifareae
Nicotine is biosynthesized from
Anonymous Quiz
36%
A).ornithine
10%
B).aspartic acid
2%
C) glyceraldehyde.
48%
D) all above
5%
E) none above
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Lobeline used by the Native Americans for
Anonymous Quiz
3%
A)asthma
2%
B)chronic bronchistis
49%
C) respiratory stimulant
45%
D)all above
❤1
Upon reduction, the tertiary base pyridine is converted into the
Anonymous Quiz
13%
A. Pyrolidine
79%
B. Piperidine
2%
C. Ornithine
6%
D. Nicotine
Lobelia plant is
Anonymous Quiz
5%
A)drived bark &tops
12%
B)drived roots&tops
74%
C)drived leaves &tops
9%
D)none above
All the followings are correct for nicotine except: -
Anonymous Quiz
6%
A.Obtained from the leaves of Nicotiana tobacco fam Solanaceae (Major)
6%
B.Liquid colorless alkaloid
5%
C.Gangelioleptic with a cardiovascular effect and increases blood pressure
56%
D.Biosynthetically derived from aspartic acid and lysine
28%
E. It is not carcinogenic
nicotine is derivatives of
Anonymous Quiz
15%
A) nicotinic acid
5%
B) pyridine
3%
C) piperidine
3%
D) pyrolidine
74%
E) both b&d
_________ is the key intermediate in biosynthesis of nicotine
Anonymous Quiz
18%
A. Ornithine
2%
B. Nicotinic acid
68%
C. N- methylpyrrolinium ion
12%
D. N-methylputrescine