هل سؤال جاي شرح+ رسم
__
1..• The importance of intestinal reduction is shown in the metabolism of sulfasalazine
2.. used : treatment of ulcerative colitis.
3.. absorbed: poorly
4.. undergoes reductive cleavage of the azo linkage to yield :
sulfapyridine and 5-aminosalicylic acid.
5..The reaction occurs:
primarily in the colon and is carried out principally by intestinal bacteria.
6.. How were the studies conducted?
Studies in germfree rats, lacking intestinal flora, have demonstrated that sulfasalazine is not reduced to any appreciable extent
__
1..• The importance of intestinal reduction is shown in the metabolism of sulfasalazine
2.. used : treatment of ulcerative colitis.
3.. absorbed: poorly
4.. undergoes reductive cleavage of the azo linkage to yield :
sulfapyridine and 5-aminosalicylic acid.
5..The reaction occurs:
primarily in the colon and is carried out principally by intestinal bacteria.
6.. How were the studies conducted?
Studies in germfree rats, lacking intestinal flora, have demonstrated that sulfasalazine is not reduced to any appreciable extent
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اللهم نسألك توفيقاً من عندك ودرجاتٌ من حيث لا ندري ، واللهم إني استودعك اجاباتي واجابات اخوتي وزملائي الطلبة فرد إلينا بأفضل النتائج ❤️❤️
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🌚💔ملازم دكتوره ضحى جايبه mcq هواي منهم ف لاتعوفون شي
وذني الفوك جايبتهم شرح مع رسم
ملازم دكتور احمد اغلبهن mcq
وجايب شرح قليل من اخر ٣ ملازم حننشر الي نتوقعه يجي
وتعيشون وتسلمون
وذني الفوك جايبتهم شرح مع رسم
ملازم دكتور احمد اغلبهن mcq
وجايب شرح قليل من اخر ٣ ملازم حننشر الي نتوقعه يجي
وتعيشون وتسلمون
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🇺🇸: pay your bills
🇸🇦: ادفع مستحقات الجامعة
🇮🇶: حجب درجات النظري
ممنوع تمتحنون وانتو مدافعين
نداء اخير الي مادافع قسط راح ينفصل
الممثل كل خمس دقايق ينزل اسمائكم
الي مادافع قسط ميستلم نتيجته
حجب النتيجة + فلقة واربعين جلدة
🇸🇦: ادفع مستحقات الجامعة
🇮🇶: حجب درجات النظري
ممنوع تمتحنون وانتو مدافعين
نداء اخير الي مادافع قسط راح ينفصل
الممثل كل خمس دقايق ينزل اسمائكم
الي مادافع قسط ميستلم نتيجته
حجب النتيجة + فلقة واربعين جلدة
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In general, structural chnnges In the barbiturate serien that favor partitioning into the libid tissue storesd
Anonymous Quiz
68%
decrease duration of action but increase central nervous system (CNS) depressio
15%
Increase duration of action but increase central nervous system (CNS) depression.
8%
decrease duration of action but decrease central nervous system (CNS) depression.
9%
Increase duration of action but decrease central nervous system (CNS) depressio
❤1👍1
In general, structural changes in the barbiturate series that favor partitioning into the lipid tissue stores
decrease duration of action but increase central nervous system (CNS) depression.
decrease duration of action but increase central nervous system (CNS) depression.
Anonymous Quiz
94%
T
6%
F
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An understanding of the metabolic labile site on lidocaine led to the development of the primary amine prodrug tocainide.
Anonymous Quiz
87%
T
13%
F
❤2
An understanding of the metabolic labile site on lidocaine led to the development of:
A- the quaternary ammonium analog tocanidc. B- The secondary amine prodrug tocainide.
C- The tertiary amine prodrug tocainidc. D-The primary amine analog tocainidc.
A- the quaternary ammonium analog tocanidc. B- The secondary amine prodrug tocainide.
C- The tertiary amine prodrug tocainidc. D-The primary amine analog tocainidc.
Anonymous Quiz
13%
A
6%
B
13%
C
68%
D
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A study of the metabolic fate of a drug is required for all new drug products. Often it is found that the metabolites are also active.
Anonymous Quiz
93%
T
8%
F
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Examples of an inactive parent drug that is converted to an active metabolite include the nonsteroidal anti-inflammatory agent sulindac being reduced to the active
Anonymous Quiz
19%
A. Sulfone metabolite
64%
B. sulfide metabolite.
14%
C. Sulfoxide metabolite.
3%
D. Sulfhydryl metabolite.
❤1
In the tcracyclic antidepressant series, imipraminc and nortriptyline amitriptyline arc N-demethylated
to desipraminc and, respectively All four compounds have been marketed in the United Slates.
to desipraminc and, respectively All four compounds have been marketed in the United Slates.
Anonymous Quiz
68%
T
32%
F
In the tricyclic antidepressant secies imipramine and amitriptyline are N-demethylated to
A- Nortriptyline and Dcsipramlne. B-desipramine and Nortriptyline
C-Mapritylmc and Dcsipramine. D-Desipramine and Mapritylmc.
A- Nortriptyline and Dcsipramlne. B-desipramine and Nortriptyline
C-Mapritylmc and Dcsipramine. D-Desipramine and Mapritylmc.
Anonymous Quiz
26%
A
61%
B
10%
C
2%
D
❤2
Nursing mothers must be concerned, because drugs and their metabolites can be excreted in human milk and be ingested by the nursing infant.
Anonymous Quiz
89%
T
11%
F
Receptors include a relatively small region of a macromolecule, which may be an:
Anonymous Quiz
11%
A- Isolatable enzyme.
7%
B- A structural & functional component of a cell membrane.
11%
C- A specific intracellular substance such as a protein or nucleic acid.
68%
D- All ofabove.
2%
E-Not ofabove.
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The more advanced method of receptor isolation
Anonymous Quiz
25%
A affinity chromatography.
6%
B thin layer chromatography.
37%
C recombinant dna
28%
D all above
5%
E non of above
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