is useful in treatment of polycystic ovary syndrome

Hypoglycemia doesn’t occur when metformin is taken with insulin

is not bound to serum proteins, and is not metabolized. Excretion is via the urine

pioglitazone and rosiglitazone are with groups called

Metformin should be used with caution in patients less than 80 years and in those HF or alcohol abuse

Block k channel and open Ca channel is

Pioglitazone act to inhibit PPARY

Pioglitazone and rosiglitazone are undergo extensive metabolism by different CYP450 isozymes

Emapagliflozin act to treatment Type2 diabetes and indicated to reduce the risk of cardiovascular disease

All DPP-4 inhibitors except linagliptin require dosage adjustments in renal dysfunction

Canagliflozin should be taken after the first meal

Acarbose inhibit of Alfa glucosidase enzyme

Metformin doesn’t produce problem such as lactic acid

Oral Antibiotic drugs act on Type2 diabetes are

Insulin resistance: failure of body cell to response to insulin in endogenous or exogenous insulin

is peptides secreted from Small intestine in response to CHO and stimulate beta cell to release insulin and inhibit glucagon and inhibit appetite and slows gastric emptying

Regular insulin is a short-acting, soluble, crystalline zinc insulin ,Insulin lispro, aspart, and glulisine are classified as rapid-acting insulins.

Modification of the amino acid sequence of regular insulin produces analogs that are short-acting insulins.

Peak levels of insulin lispro are seen at 30 to 90 minutes, as compared with 50 to 120 minutes for regular insulin

Insulin aspart and insulin glulisine have pharmacokinetic and pharmacodynamic properties similar to those of insulin lispro

Inhaled insulin is also considered short-acting