محاضرة ال Suppository

1_Vaginal suppositories, also
called (.....), are usually
globular, oviform, or cone-
shaped and weigh about (.....)
when cocoa butter is the
base.


Pessaries _5g

2_Urethral suppositories, also called (....)

Bougies

4_Male urethral suppositories may be 3 to 6 mm in diameter and approximately (...) mm
long, and weigh about (...)

140mm
4g

3_Rectal suppositories intended for local action are most frequently used to relieve (....) And other such as (....)


Irritating or pain or hemorrhage

5_chlorpromazine effect used for?

Antivomting and nasua

6_Rectal absorption dependend on two factors they are (..) and (..)

Physiology,physicochemical

7_Drugs absorbed rectally, unlike those absorbed after oral administration why?

Because they don’t go to fiest bypass metabolism

8_Miscellaneous bases, generally combinations of (...) and
(...) substances.

Lipophlic and hydrophilic

9_Polyethylene glycols are polymers of (...) and (..)

Ethylene oxide and water

What is the purpose of the urethral suppositories ?
Universe local anesthetic

Which route rectal or vaginal is used more often for systemic application? suppositories Add administrated
urethral ,rectal, vaginal

Which spit suppository route would be used for nausea and vomiting? Compazine :
prochlorperazine, Ondansetron

Which suppositories is used for anti-inflammatory Drug? Indomethacin

Why does an empty rectal higher better absorption? Because anempty has better absorption and there is more available surface area of the colon the wall

What are the conditional and flus absorption? Diarrhea tumors tissue dehydration

How does the drug avoid that first pass effect? The first pass effect is avoided by being absorbed through hemorrhoidal veins at the lower part of the rectum

What happens to absorption if they’re suppository to is a place to high in the rectum? The drug well under go first pass effect

What is another route of absorption of rectal suppositories? Absorption occurs through lymphatic circulation as well

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