Forwarded from ً
Among the physiological factors that affect drug absorption from the rectum are:
Anonymous Quiz
7%
pH and lack of buffering capacity of the rectal fluids.
4%
Circulation route
3%
Colonic content.
86%
All of above
Forwarded from ً
In systemic effects , if the rectum void we get on ..... Absorption
Anonymous Quiz
24%
Decreased
57%
Increase
8%
Non effects
12%
The fecal non effects in absorption
Forwarded from ً
an evacuant enema may be administered and allowed to act before the administration of a suppository of a drug to be absorbed
Anonymous Quiz
87%
True ☑️
13%
False 😔
Forwarded from ً
Drugs absorbed rectally are avoided portal circulation and thus minimizing first-pass effect
Anonymous Quiz
79%
True ☺️
21%
False ❌
😁1
Forwarded from ً
Physicochemical factors of the drug includes such all properties except
Anonymous Quiz
8%
Amount of the drug
17%
pKa of the drug
7%
The relative solubility of the drug in lipid and in water
57%
Rheological properties
11%
The particle size of a dispersed drug and surface properties.
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Physicochemical factors of the base include all except
Anonymous Quiz
5%
1. Its ability to dissolve at body temperature
28%
Rheological properties
48%
Amount of drug
3%
composition of the base
16%
All of above
Forwarded from ً
Rheological properties are the physicochemical factor of
Anonymous Quiz
61%
The base
12%
The drug
25%
Both
2%
None
Forwarded from ً
If the drug has low solubility in both fat and water, the preferred base is
Anonymous Quiz
7%
Aqueous base
68%
Intermediate base
10%
Fatty base
15%
All of above
Forwarded from ً
We use a fatty Base if Solubility in fat and water respectively
Anonymous Quiz
8%
Low , low
6%
High, high
53%
Low, high
32%
High, low
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According to the Particle size of drugs which are/is true
Anonymous Quiz
7%
Particles of drug effects on the availability only
6%
Greater particle size gives greater surface area
39%
the more readily dissolution of The particles give a greater chance for rapid absorption
35%
B&C
12%
All of above
Forwarded from ً
All are true about the ideal suppository base except
Anonymous Quiz
5%
non irritating to sensitive and inflamed tissues.
9%
Not contaminating the drug during storage
7%
Inert and compatible with the medications
30%
Stable on storage, change color, odor and drug release pattern
48%
All of the above are true
Forwarded from ً
Ideal suppository base deffeculty manufactured by compression or molding.
Anonymous Quiz
61%
False ❌
39%
True ☑️
Forwarded from ً
Types of suppository base are
Anonymous Quiz
5%
Oleaginous or fatty base
2%
Miscellaneous base
5%
Water soluble or miscible base
88%
All of above
Forwarded from ً
Theobromine oil is an example of
Anonymous Quiz
8%
Water soluble base
13%
Miscellaneous base
74%
Fatty base
5%
None of above
Forwarded from ً
...... Are/ is an example (s) of water soluble base
Anonymous Quiz
9%
Cocoa butter
10%
Glycerinated gelatin
13%
Polyethylene glycol
62%
B&C
6%
All of above
Forwarded from ً
Miscellaneous base is
Anonymous Quiz
11%
Glycerinated gelatin is an example of it
76%
Combination of lipophilic and hydrophilic substance
6%
Appears to be the superior base
8%
Required temperature about 35 C⁰
👍1
1_Vaginal suppositories, also
called (.....), are usually
globular, oviform, or cone-
shaped and weigh about (.....)
when cocoa butter is the
base.
Pessaries _5g
2_Urethral suppositories, also called (....)
Bougies
4_Male urethral suppositories may be 3 to 6 mm in diameter and approximately (...) mm
long, and weigh about (...)
140mm
4g
3_Rectal suppositories intended for local action are most frequently used to relieve (....) And other such as (....)
Irritating or pain or hemorrhage
5_chlorpromazine effect used for?
Antivomting and nasua
6_Rectal absorption dependend on two factors they are (..) and (..)
Physiology,physicochemical
7_Drugs absorbed rectally, unlike those absorbed after oral administration why?
Because they don’t go to fiest bypass metabolism
8_Miscellaneous bases, generally combinations of (...) and
(...) substances.
Lipophlic and hydrophilic
9_Polyethylene glycols are polymers of (...) and (..)
Ethylene oxide and water
What is the purpose of the urethral suppositories ?
Universe local anesthetic
Which route rectal or vaginal is used more often for systemic application? suppositories Add administrated
urethral ,rectal, vaginal
Which spit suppository route would be used for nausea and vomiting? Compazine :
prochlorperazine, Ondansetron
Which suppositories is used for anti-inflammatory Drug? Indomethacin
Why does an empty rectal higher better absorption? Because anempty has better absorption and there is more available surface area of the colon the wall
What are the conditional and flus absorption? Diarrhea tumors tissue dehydration
How does the drug avoid that first pass effect? The first pass effect is avoided by being absorbed through hemorrhoidal veins at the lower part of the rectum
What happens to absorption if they’re suppository to is a place to high in the rectum? The drug well under go first pass effect
What is another route of absorption of rectal suppositories? Absorption occurs through lymphatic circulation as well
called (.....), are usually
globular, oviform, or cone-
shaped and weigh about (.....)
when cocoa butter is the
base.
Pessaries _5g
2_Urethral suppositories, also called (....)
Bougies
4_Male urethral suppositories may be 3 to 6 mm in diameter and approximately (...) mm
long, and weigh about (...)
140mm
4g
3_Rectal suppositories intended for local action are most frequently used to relieve (....) And other such as (....)
Irritating or pain or hemorrhage
5_chlorpromazine effect used for?
Antivomting and nasua
6_Rectal absorption dependend on two factors they are (..) and (..)
Physiology,physicochemical
7_Drugs absorbed rectally, unlike those absorbed after oral administration why?
Because they don’t go to fiest bypass metabolism
8_Miscellaneous bases, generally combinations of (...) and
(...) substances.
Lipophlic and hydrophilic
9_Polyethylene glycols are polymers of (...) and (..)
Ethylene oxide and water
What is the purpose of the urethral suppositories ?
Universe local anesthetic
Which route rectal or vaginal is used more often for systemic application? suppositories Add administrated
urethral ,rectal, vaginal
Which spit suppository route would be used for nausea and vomiting? Compazine :
prochlorperazine, Ondansetron
Which suppositories is used for anti-inflammatory Drug? Indomethacin
Why does an empty rectal higher better absorption? Because anempty has better absorption and there is more available surface area of the colon the wall
What are the conditional and flus absorption? Diarrhea tumors tissue dehydration
How does the drug avoid that first pass effect? The first pass effect is avoided by being absorbed through hemorrhoidal veins at the lower part of the rectum
What happens to absorption if they’re suppository to is a place to high in the rectum? The drug well under go first pass effect
What is another route of absorption of rectal suppositories? Absorption occurs through lymphatic circulation as well
❤4👍1
Forwarded from طـن أمسكيوات
Ttrue solution:
Anonymous Quiz
44%
Lotions
5%
Suspensions
8%
Emulsions
33%
All of above
10%
Non of above
Forwarded from طـن أمسكيوات
lotions may be sometimes preferred over semisolid preparations such as ointments and creams due to
Anonymous Quiz
7%
non-greasy character
24%
increased spreadability over large areas of the skin
69%
all
😍1