47.3 Which statement best describes the mechanism of action of pyrantel pamoate?
A. Acts as a depolarizing neuromuscular blocking agent leading to paralysis of the worm
B. Binds to B-tubulin and inhibits the assembly of the microtubules polymerization in the parasite
C. Inhibits the mitochondrial phosphorylation of adenosine diphosphate (ADP) in the parasite D. Inhibits glucose uptake leading to parasite death
A. Acts as a depolarizing neuromuscular blocking agent leading to paralysis of the worm
B. Binds to B-tubulin and inhibits the assembly of the microtubules polymerization in the parasite
C. Inhibits the mitochondrial phosphorylation of adenosine diphosphate (ADP) in the parasite D. Inhibits glucose uptake leading to parasite death
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47.4 Which is the best treatment option for treatment of cutaneous larva migrans?
A. Pyrantel pamoate
B. Diethylcarbamazine
C. Ivermectin
D. Niclosamide
A. Pyrantel pamoate
B. Diethylcarbamazine
C. Ivermectin
D. Niclosamide
47.5 Which medication used to treat river blindness targets chloride channels and can cause a Mazzotti reaction?
A. Ivermectin B. Praziquantel
C. Pyrantel pamoate D. Albendazole
A. Ivermectin B. Praziquantel
C. Pyrantel pamoate D. Albendazole
47.6 A 48-year-old immigrant from Mexico presents with seizures and other neurologic symptoms. Eggs of Taenia solium are found in a stool specimen. A magnetic resonance image of the brain shows many cysts, some of which are calcified. Which drug would be of benefit to this individual?
A. Ivermectin
B. Pyrantel pamoate
C. Albendazole
D. Diethylcarbamazine
A. Ivermectin
B. Pyrantel pamoate
C. Albendazole
D. Diethylcarbamazine
47.7 Which drug works by increasing the permeability of the cell membrane to calcium?
A. Albendazole
B. Ivermectin
C. Niclosamide
D. Praziquantel
A. Albendazole
B. Ivermectin
C. Niclosamide
D. Praziquantel
Pharma Scope
47.7 Which drug works by increasing the permeability of the cell membrane to calcium? A. Albendazole B. Ivermectin C. Niclosamide D. Praziquantel
🛑 الجواب Praziquantel لان يزود من permeability of the cell membrane to calcium
47.8 When used for treatment of taeniasis, a laxative is usually administered prior to oral administration of which
drug?
A. Mebendazole
B. Diethylcarbamazine
C. Niclosamide
D. Pyrantel pamoate
drug?
A. Mebendazole
B. Diethylcarbamazine
C. Niclosamide
D. Pyrantel pamoate
47.9 A 37-year-old man presents with diarrhea and gastrointestinal bleeding. Eggs of Schistosoma mansoni are found upon examination of a stool specimen. The patient has a history of seizures and is currently on phenytoin. Metabolism of which medication will be increased due to his current drug regimen?
A. Ivermectin B. Praziquantel
C. Thiabendazole D. Niclosamide
A. Ivermectin B. Praziquantel
C. Thiabendazole D. Niclosamide
47.10 When used for longer treatment, such as hydatid disease, which medication is associated with risks of hepatotoxicity and agranulocytosis?
A. Albendazole
B. Diethylcarbamazine
C. Niclosamide D. Ivermectin
A. Albendazole
B. Diethylcarbamazine
C. Niclosamide D. Ivermectin