Pharma Scope
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47.1 A 32-year-old man is diagnosed with whipwom disease after he spent the summer working outside without shoes. Which would be the best treatment option?

A. Pyrantel pamoate
B. Mebendazole
C. Thiabendazole
D. Diethylcarbamazine
47.2 Which combination would be appropriate to use for preventative chemotherapy in countries with endemic filariasis and endemic onchocerciasis?

A. Pyrantel pamoate and mebendazole

B. Ivermectin and diethylcarbamazine
C. Albendazole and diethylcarbamazine

D. Ivermectin and albendazole
47.3 Which statement best describes the mechanism of action of pyrantel pamoate?

A. Acts as a depolarizing neuromuscular blocking agent leading to paralysis of the worm

B. Binds to B-tubulin and inhibits the assembly of the microtubules polymerization in the parasite

C. Inhibits the mitochondrial phosphorylation of adenosine diphosphate (ADP) in the parasite D. Inhibits glucose uptake leading to parasite death
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47.4 Which is the best treatment option for treatment of cutaneous larva migrans?

A. Pyrantel pamoate

B. Diethylcarbamazine

C. Ivermectin

D. Niclosamide
مادة جافة طبعاً
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47.5 Which medication used to treat river blindness targets chloride channels and can cause a Mazzotti reaction?

A. Ivermectin B. Praziquantel

C. Pyrantel pamoate D. Albendazole
47.6 A 48-year-old immigrant from Mexico presents with seizures and other neurologic symptoms. Eggs of Taenia solium are found in a stool specimen. A magnetic resonance image of the brain shows many cysts, some of which are calcified. Which drug would be of benefit to this individual?

A. Ivermectin

B. Pyrantel pamoate

C. Albendazole

D. Diethylcarbamazine
نسيت بعد اكو 😂💔
47.7 Which drug works by increasing the permeability of the cell membrane to calcium?
A. Albendazole

B. Ivermectin

C. Niclosamide

D. Praziquantel
47.8 When used for treatment of taeniasis, a laxative is usually administered prior to oral administration of which

drug?
A. Mebendazole

B. Diethylcarbamazine

C. Niclosamide
D. Pyrantel pamoate
47.9 A 37-year-old man presents with diarrhea and gastrointestinal bleeding. Eggs of Schistosoma mansoni are found upon examination of a stool specimen. The patient has a history of seizures and is currently on phenytoin. Metabolism of which medication will be increased due to his current drug regimen?

A. Ivermectin B. Praziquantel

C. Thiabendazole D. Niclosamide