Patho pearls πŸ”¬πŸΌ
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Which of the following markers is specific for gastro-intestinal stomal tumor (GIST) -
Anonymous Quiz
60%
CD 117
21%
CD 34
8%
CD 23
11%
S-100
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Gene deleted in clear cell RCC?
Anonymous Quiz
34%
3p
10%
7/17
11%
FH gene
46%
VHL gene
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Burt hugg dube syndrome associated with?
Anonymous Quiz
56%
Chromophobe type
19%
Papillary type
17%
Clear cell type
8%
Nephroblastoma
Benign tumor associated with tuberous sclerosis
Anonymous Quiz
53%
Angiomyolipoma
15%
Oncocytoma
20%
Nephroblastoma
11%
Papillary adenoma
Lacunar cells is seen in which type of
Hodgkins Lymphoma:
Anonymous Quiz
14%
Mixed cellularity type
24%
Lymphocyte predominant
45%
Nodular Sclerosis Type
17%
All of the above
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Leukocyte migration through endothelium is induced by ?
Anonymous Quiz
8%
N CAM
33%
Selectin
14%
C CAM
46%
PECAM
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Ans? A or B
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Which is nuclear neuroendocrine immunohistochemistry marker
Anonymous Quiz
19%
NCAM1
25%
INSM1
36%
Chromogranin
19%
Synaptophysin
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Not a marker for GIST
Anonymous Quiz
21%
SDH
41%
NRG1
26%
PDGFRA
12%
KIT
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55 year male having massive splenomegaly. Causes are all except
Anonymous Quiz
12%
CML
20%
Hairy cell leukemia
49%
Aplastic anemia
19%
Polycythemia
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1. Damage to nervous tissue is repaired by : Neuroglia

2. Mycosis fungoides : Cutaneous lymphoma

3. Secondary amyloidosis complicates: Chronic osteomyelitis

4. The earliest feature of TB is: Lymphocytosis

5. The low grade non-hodgkins lymphoma is : Follicular

6. Liquefactive necrosis is seen in : Brain

7. The crescent forming glomerulonephritis is: RPGN

8. Earliest feature of correction of IDA is : Reticulocytosis

9. Kupffer's cells are found in : Liver

10. Heart failure cells are found in : Lungs

11. Psammoma bodies show: Dystrophic calcification


12. Beta-microglobulin: is not a tumor marker

13. Commonest benign tumor of liver : Hemangioma

14. Blood when stored at 4 degree celcius can be kept for: 21 days

15. Congo-red with amyloid produces: Brilliant pink ccolour

16. Cloudy swelling does not occurs in : Lungs

17. Gamma Gandy bodies contains hemosiderin and : Ca++

18. Hutchinson's secondaries in skull are due to tumors in : Adrenals

19. Albumino -cytologic dissociation occurs in cases of: Guillain Barre syndrome

20. Metastatic calcification is most often seen in : Lungs

21. ASLO Titres are used in the diagnosis of: Acute rheumatic fever

22. Apoptosis is inhibited by : bcl-2

23. CEA: is not used as a tumor marker in testicular tumours

24. Onion peel appearance of splenic capsule is seen in : SLE

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HLA allele & Disease Association

βœ…HLA A3 : Hemochromatosis


βœ…HLA B8 : Myasthenia Gravis ,Graves disease

βœ…HLA B16 : Multiple sclerosis


βœ…HLA B27:
Ankylosing spondylitis, Acute anterior uveitis
Reactive arthritis,Psoriatic
arthritis

βœ…HLA B47: Congenital adrenal hyperplasia

βœ…HLA B51 : Behcet's disease

βœ…HLA B57: Abacavir Hypersensitivity

βœ…HLA CW6 : Psoriasis

βœ…HLA DQ1: Narcolepsy

βœ…HLA DQ 2 : Celiac disease

βœ…HLA DR2 : SLE(Japanese) & Sjogren Syndrome


βœ…HLA DR3 : Type I diabetes mellitus,Dermatitis herpetiformis,
Chronic active hepatitis,
Sjogren's syndrome ,SLE (white)

βœ…HLA DR4 : Rhematiod Arthritis

βœ…HLA DR5 : Pernicious Anemia , Hasimoto's Thyroiditis

βœ…HLA DR8 ,DR5 : juvenile arthritis ( pauci articular)
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