قسم pathology للدفعة الخامسة
- Identify this microscopic picture ?
●——●• OSTEOSARCOMA •●——●
#Definition
• Malignant tumor in which the cells synthesize bone
• Most common primary malignant solid tumor of bone (plasma cell myeloma is actually the most common primary bone tumor but it's not a solid tumor)
• Many types of osteosarcoma that differ based on the tumor's location (within the bone or on the surface of the bone) and the grade of the tumor (low grade, intermediate grade or high grade)
#Common features
• Bone is necessary for diagnosis (typically has a filigree microscopic appearance)
• Most cases occur in children (10 - 14 years old) and are primary; secondary osteosarcoma is most common in adults
#affected bone
• Osteosarcoma may arise in any bone
• Most common : long bones of extremities
#Clinical features
• Painful enlarging mass lesion is common
#Gross description
• originates from metaphysis of the proximal humerus, extends into surrounding soft tissues
#Microscopic description
- eosinophilic cytoplasm ( little )
- hyper-cellular
- hyper-chromatic nuclei ( large )
- spindle cells ( different sizes and shapes
الإجابه 👇🏻
#Definition
• Malignant tumor in which the cells synthesize bone
• Most common primary malignant solid tumor of bone (plasma cell myeloma is actually the most common primary bone tumor but it's not a solid tumor)
• Many types of osteosarcoma that differ based on the tumor's location (within the bone or on the surface of the bone) and the grade of the tumor (low grade, intermediate grade or high grade)
#Common features
• Bone is necessary for diagnosis (typically has a filigree microscopic appearance)
• Most cases occur in children (10 - 14 years old) and are primary; secondary osteosarcoma is most common in adults
#affected bone
• Osteosarcoma may arise in any bone
• Most common : long bones of extremities
#Clinical features
• Painful enlarging mass lesion is common
#Gross description
• originates from metaphysis of the proximal humerus, extends into surrounding soft tissues
#Microscopic description
- eosinophilic cytoplasm ( little )
- hyper-cellular
- hyper-chromatic nuclei ( large )
- spindle cells ( different sizes and shapes
الإجابه 👇🏻
Patient with osteopenia in 40 years old has a high serum calcium level .The patient has an excessive or inappropriate levels of PTH results from autonomous parathyroid secretion.
What is the most possible diagnosis for this patient?
What is the most possible diagnosis for this patient?
Anonymous Quiz
64%
hyperparathyroidism
15%
Osteopetrosis
6%
Osteogenesis Imperfecta
15%
osteoporosis
س/ م فهمتش المقصود ؟!
ج/هنا علئ ما هوه مكتوب انه اول شي سبب هذا المرض هوه الطفره في جين FGFR3 الذي يعمل هذا الجين علئ تثبيط النموء الغضروفي وعند ما يحصل طفره فيه يعمل علئ تنشيط المستقبل وبهذا الطريقه يحدث التاثير الذي هوه كبح او تثبيط النموء ..
هذا مو مكتَوب ..
#من_اسئلتكم
#فريق_التقوية
ج/هنا علئ ما هوه مكتوب انه اول شي سبب هذا المرض هوه الطفره في جين FGFR3 الذي يعمل هذا الجين علئ تثبيط النموء الغضروفي وعند ما يحصل طفره فيه يعمل علئ تنشيط المستقبل وبهذا الطريقه يحدث التاثير الذي هوه كبح او تثبيط النموء ..
هذا مو مكتَوب ..
#من_اسئلتكم
#فريق_التقوية
قسم pathology للدفعة الخامسة
Photo
What is this disease?
Anonymous Quiz
76%
Rickets
9%
Osteomalacia
11%
osteoporosis
5%
hyperparathyroidism
السلام عليكم ورحمة الله وبركاته
رجعنا معكم مع معمل الباثو الثاني في فقرة
#الجواب_عليك
#الشرح_علينا
طبعاً بيكون الموضوع عن الـ cartilage forming tumors وكذا بنكون خلصنا
ارسلوا إجابتكم على بوت القناة 🌚👇🏻
@path50bot
رجعنا معكم مع معمل الباثو الثاني في فقرة
#الجواب_عليك
#الشرح_علينا
طبعاً بيكون الموضوع عن الـ cartilage forming tumors وكذا بنكون خلصنا
ارسلوا إجابتكم على بوت القناة 🌚👇🏻
@path50bot