المعمل الثاني باثو

#اللجنة_العلمية_للدفعة_الخامسة
#قسم_الباثو
#عملي

تسجيل المحاضرة الثانية
2021/10/19
#اللجنة_العلمية_للدفعة_الخامسة
#قسم_الباثولوجي
#قسم_التسجيلات

السلام عليكم ورحمة الله وبركاته
رجعنا معكم مع معمل الباثو الثاني في فقرة
#الجواب_عليك
#الشرح_علينا

طبعاً بيكون الموضوع عن الـ Bone forming tumors فقط والتكملة في المره القادمه

ارسلوا إجابتكم على بوت القناة 🌚👇🏻

@path50bot

1- Diagnosis

2- Causes

3- Common features

4- Identify the arrow

5- Treatment

6- affected bones

7- Common in

1- Diagnosis

2- Common features

3- Identify each arrow

Draw arrow identify the site of thick sclerotic bone

1- Diagnosis

2- affected bones

3- Clinical features

4- common features

1- Diagnosis

2- Identify the arrows

- Identify this microscopic picture ?

1- Diagnosis

2- Causes

3- Common in

ملزمه رهيبه جدا جدا خاصه في أورام العضام بيفيدكم جدك في العملي كمان اطلعو عليها ✨✨✨👍

#اللجنة_العلمية_للدفعة_الخامسة
#قسم_الباثو

السلام عليكم ورحمة الله وبركاته

رجعنا معكم في فقرة
#الجواب_عليك
#الشرح_علينا

وبيكون اليوم الشرح علينا ان شاء الله 🌚✨

●————●• OSTEOMA •●————●

#Definition
○ Benign, bone forming tumor composed of mature cortical type or less frequently, trabecular bone, typically involving the craniofacial skeleton

كمان هو تكون قطه جديدة من العظم ( new piece of bone ) فوق عظم اخر واكثر شيوعاً تكون في عظمة الجمجمة وهو ( benign tumor )

طيب ليه اسمين على حسب مكان نموه 👇🏻
١- لما يكون نمو العظم على عظم يسمى ( homoplastic osteoma )
٢- لما ينمو على نسيج اخر حينها نسميه ( heteroplastic osteoma )

#Causes
• Still unclear

#Common features
• Benign osteogenic tumor
• Usually involves the surface of craniofacial bones
• Admixture of mature lamellar and woven bone patterns, with Haversian-like canals
• Cortical type bone architecture is typical
• Lack of cellular atypia


#Clinical features
• Depending on the size and location, it can cause headache, facial pain, obstruction of paranasal sinuses, vision disturbancies, interference with mastication


#Treatment
• Observation for asymptomatic cases
• Surgical excision for symptomatic cases

#Affected bone
• craniofacial bone


#Common in
Older ( from 40 to 50 years ) and slight males predominance.

#Gross description
• Typically a solitary lesion Tan-white
• Oval, round or polypoid
• Firm
• Well circumscribed and attached to the underlying bone
• Cut surface with dense compact bone or trabecular bone

#Microscopic description
• Admixture of mature lamellar and woven bone patterns, with Haversian-like canals, which may have various sizes and shapes
• More frequent: cortical type bone architecture
• Less frequent: trabecular bone architecture
• Osteoblasts rimming bone are inconspicuous and small but can be prominent in growing lesions
• Osteocytes in the matrix are small,
• Intertrabecular marrow spaces are filled with moderately cellular, loose fibrous stroma
• Inflammatory infiltrates are typically absent

الإجابة 👇🏻

1- Diagnosis 👉🏻 osteoma

2- Causes 👉🏻 unclear

3- Common features 👉🏻
1- Haversian system varies in sizes and shapes ( irregular )
2- have few osteocytes


4- Identify the arrow 👉🏻 Haversian like canal

5- Treatment 👉🏻 surgery

6- affected bones 👉🏻 ‏ ‏craniofacial bone


7- Common in 👉🏻 Older ( from 40 to 50 years ) and slight males predominance.

●—●• OSTEOID OSTEOMA •●—●

#Definition
• Small, benign, bone forming tumor associated with pain and limited growth potential
• Nidus < 2 cm (any larger size arbitrarily considered to be an osteoblastoma)
• It won't spread to other bones or parts of your body.

#Causes
• unclear . They seem to start with inflammation in the bone

#Clinical features
• Intense localized pain, worse at night, relieved by NSAIDs This Pain due to production of prostaglandin E2 in reactive zone
• Juxta - articular tumors with arthritis or joint dysfunction
• Vertebral tumors with scoliosis

#treatment
CT localization with excision or radiofrequency ablation, or medical management alone

#affected bone
• femur and tibia most common
• Virtually any bone can be affected


#Common in
• Children, adolescents and young adults (most patients 5 - 24 years old)
• male more than female


#Gross description
• Small circumscribed nidus with surrounding sclerosis (intact specimen)
• Most often received as red, gritty fragments post curettage

#Microscopic description
• Small, circumscribed
• Anastomosing, irregular trabeculae or solid, sclerotic nidus of woven bone with variable mineralization
• Rimmed by single layer of osteoblasts plus frequent osteoclasts
• Loose, fibrovascular stroma
• Surrounded by thick sclerotic bone

الإجابه👇🏻

1- Diagnosis 👉🏻 osteoid osteoma

2- Common features 👉🏻
A- irregular trabecular or solid
B- loose fibrovascular stroma
C- surrounded by thick sclerotic bone
D- single layer of osteoblasts + frequent osteoclasts

3- Identify each arrow
- black arrow 👉🏻 osteoblasts and osteocytes
- green arrow 👉🏻 irregular trabecular

1- Diagnosis 👉🏻 nidus

2- affected bones 👉🏻 femur and tibia most common and virtually and any bone

3- Clinical features 👉🏻 pain worse at night

4- common features 👉🏻
1- appears entirely in the cortex
2- red gritty ( color )
3- surrounding by sclerosis