#GROSS

#Diagnosis → classic seminoma germ cell neoplasm

#The_black_areas
Rounded lobulated yellow-white masses

#Features
No necrosis
No haemorrhage
Well circumscribed

#MICROSCOPIC

#Diagnosis → classic seminoma germ cell neoplasm

#The_blue_arrows
Inflammatory cells (lymphocytes)

#The_black_arrow
Fibrous septae (pink in color)

#MICROSCOPIC

#Diagnosis → classic seminoma germ cell neoplasm

#The_blue_arrows
Inflammatory cells (lymphocytes)

#The_black_arrow
Fibrous septae (pink in color)

#The_brown_arrows
Prominent nucleoli with clear cytoplasm

#MICROSCOPIC

#Diagnosis → spermatocytic tumour

#The_blue_arrow
bizzar nucleus cell

#Features
Highly pleomorphism
Prominent nucleoli with clear cytoplasm
Hyperchromatic cells
NO INFLAMMATORY CELLS
NO FIBROUS SEPTAE

#GROSS

#Diagnosis → non seminoma yolk sac tumour

#The_blue_arrow
Haemorrhage

#The_black_arrow
Necrosis

#The_brown_arrows
Cystic areas

#Features
Irregular, ill-defined shape
Poorly circumscribed

#MICROSCOPIC

#Diagnosis → non seminoma yolk sac tumour

#The_blue_arrows
Hyalinized stroma (pink, AFP)

#The_black_arrows
Schiller Duval bodies (red)

#Features
Small hyperchrmatic pleomorphism cells
It has a papillary structure with Schiller Duval body inside

✓ Alfa fetoprotein is elevated

#MICROSCOPIC

#Diagnosis → non seminoma yolk sac tumour

#The_blue_arrows
Cancer cells

#The_black_arrow
Schiller Duval body

#MICROSCOPIC

#Diagnosis → non seminoma yolk sac tumour

#The_black_arrows
Schiller Duval bodies in tubular (finger-like) structure

#MICROSCOPIC

#Diagnosis → non seminoma yolk sac tumour

#The_black_arrows
Hyalinized stroma in globular structure

#The_brown_arrows
Cancer cells

#GROSS

#Diagnosis → non seminoma embryonal carcinoma

#The_blue_arrows
Necrosis

#The_black_arrows
Haemorrhage

#Features
It has a worse prognosis than yolk sac tumour

#MICROSCOPIC

#Diagnosis → non seminoma embryonal carcinoma

#The_black_arrows
RBCs

#Features
It has a papillary structure but without Schiller Duval body inside
Its cells larger than yolk sac's cells

#GROSS

#Diagnosis → non seminoma choriocarcinoma

#Features
Soft friable tumor
Severe haemorrhage
It forms placental tissue

#MICROSCOPIC

#Diagnosis → non seminoma choriocarcinoma

#The_brown_arrows
Haemorrhage

#The_black_arrow
Cytotrophoblast
- clear cytoplasm
- irregular nuclei
- Prominent nucleoli

#The_blue_arrows
Syncytiotrophoblast
- larger cell with numerous nuclei
- hyperchromatic nucleus
- smudge chromatin
- elongated cytoplasm

#MICROSCOPIC

#Diagnosis → non seminoma choriocarcinoma

#The_brown_area
Haemorrhage & necrosis

#The_black_arrow
Cytotrophoblast

#The_blue_arrows
Syncytiotrophoblast

#GROSS

#Diagnosis → teratoma

#Features
It contains parts from the three embryonal layers: ectoderm, mesoderm, endoderm

#GROSS

#Diagnosis 👉🏻 Normal prostate


#The_red_arrow
Central urethra

#The_green_arrow
Posterior lobe

#The_black_arrow
Left lateral lobe

#The_blue_arrow
Right lateral lobe

#MICROSCOPIC

#Diagnosis 👉🏻 Normal prostate


#The_blue_arrow
fibromuscular stroma

#The_red_area
prostate glands

#The_black_arrow
concretion

#The_brown_arrows
Columnar epithelium

#The_features
- Well differentiated glands with tall columnar epithelial lining cells.
- The cells do not have prominent nucleoli.

#MICROSCOPIC

#Diagnosis 👉🏻 Chronic prostatitis

#The_black_arrow
Lymphocytes

#The_blue_arrow
Hemorrhage

#The_features
Lymphocytes (small dark blue)  are seen in the stroma

BENIGN PROSTATIC HYPERPLASIA
( NODULAR PROSTATIC HYPERPLASIA)


✫ Gross description
- Enlarged prostate
- Multiples Nodules

✫Microscopic description
- corpora amylacea
- Columnar epithelium layer
- Myoepithelium layer (flat)
- Lumen dilution
فكونت papillary
- Glandular proliferative
- Stroma proliferative (Cellularity hyperplasia)

#GROSS

#Diagnosis 👉🏻 nodular prostatic hyperplasia

#The_black_arrows
Nodules

#MICROSCOPIC

#Diagnosis 👉🏻 nodular prostatic hyperplasia


#The_black_arrow
Hyalinosis (corpora amylacea)

#The_blue_arrow
Columnar epithelium layer

#The_red_arrow
Myoepithelium layer

#The_green_arrows
Cellularity hyperplasia