THE SECOND LAB DONE  ✓✓

#MICROSCOPIC

#Diagnosis → Koilocytosis

#The_black_arrows
Clear zone

#Features
Hyperchromatic
Pleomorphism
Clear zone around the nucleus

#MICROSCOPIC

#Diagnosis → Penile intraepithelial neoplasia

#The_black_arrow
Parakeratosis

#The_blue_arrows
Papillomatosis (finger-like)

#The_brown_area
Acanthosis

#The_orang_arrows
Koilocytosis

#MICROSCOPIC

#Diagnosis → Penile intraepithelial neoplasia

#The_black_arrows
Parakeratosis

#The_orang_arrows
Keratosis

#MICROSCOPIC

#Diagnosis → well differentiated squamous cell carcinoma (grade 1)

#The_black_arrows
Keratin pearls

#The_blue_arrow
Nest of squamous cells with eosinophilic cytoplasm

#Most_commen_cause
HPV

#MICROSCOPIC

#Diagnosis → moderate differentiated SCC (grade 2)

#The_black_arrows
Keratin pearls

#Features
Nuclear atypia
Nuclear pleomorphism
Irregular nuclear membrane
It has keratin pearls less than SCC grade 1

#MICROSCOPIC

#Diagnosis → poor differentiated SCC (grade 3)

#Features
Distributed cells
Nuclear atypia
Nuclear pleomorphism
NO KERATIN PEARLS
NO SQUAMOUS NESTS

NORMAL TESTS

NORMAL TESTS

#GROSS

#Diagnosis → testicular TB


Caseous necrosis has cheese-like appearance

#MICROSCOPIC

#Diagnosis → testicular TB

#The_black_area
Hematogenous area with less nucleus

#GROSS

#Diagnosis → cryptorchidism

#Left_testes
Atropic
Pale white in color

#MICROSCOPIC

#Diagnosis → cryptorchidism

#The_black_rhomboid
Atrophic tubule with no spermatogenesis

#The_blue_arrows
Pale stroma

#MICROSCOPIC

#Diagnosis → intratubular germ cell neoplasia

#Features
الخلايا السرطانية لازالت في الـ tubule
(no invasion)
Clear cytoplasm
Round prominent nucleoli

#MICROSCOPIC

#Diagnosis → intratubular germ cell neoplasia

#The_black_arrows
Prominent nucleoli with clear cytoplasm

#The_blue_arrows
The border of the tubule

▪️classic Seminoma

- has good prognosis
- patients 30-40 years old
- tumor marker is PAP (prostatic alkaline phosphatase)


#gross features
- yellowish- white mass
- lobulated
- well circumscribed
- No hemorrhage, No necrosis

#microscopic features
- large round cells
- large nuclei ( hyperchromatic)
- prominent nucleoli
- clear cytoplasm
- cells arranged in sheets or lobules with septa in between
- lymphocyte within the septa

#GROSS

#Diagnosis → classic seminoma germ cell neoplasm

#The_black_areas
Rounded lobulated yellow-white masses

#Features
No necrosis
No haemorrhage
Well circumscribed

#MICROSCOPIC

#Diagnosis → classic seminoma germ cell neoplasm

#The_blue_arrows
Inflammatory cells (lymphocytes)

#The_black_arrow
Fibrous septae (pink in color)

#MICROSCOPIC

#Diagnosis → classic seminoma germ cell neoplasm

#The_blue_arrows
Inflammatory cells (lymphocytes)

#The_black_arrow
Fibrous septae (pink in color)

#The_brown_arrows
Prominent nucleoli with clear cytoplasm

#MICROSCOPIC

#Diagnosis → spermatocytic tumour

#The_blue_arrow
bizzar nucleus cell

#Features
Highly pleomorphism
Prominent nucleoli with clear cytoplasm
Hyperchromatic cells
NO INFLAMMATORY CELLS
NO FIBROUS SEPTAE

#GROSS

#Diagnosis → non seminoma yolk sac tumour

#The_blue_arrow
Haemorrhage

#The_black_arrow
Necrosis

#The_brown_arrows
Cystic areas

#Features
Irregular, ill-defined shape
Poorly circumscribed