PAPILLARY RENAL CELL CARCINOMA


✫ Gross description
- Well circumscribed with pseudo capsule
- Tan yellow to red brown
- hemorrhage
- Necrosis
- Aries from cells of renal tubules

✫Microscopic description
- Small cuboidal cells arranged on single layer on papillary cores
- Cells are small with uniform
- Scant pale (not clear) cytoplasm
- hyperchromatic nuclei without nucleoli
- Papillary cores often contain foamy macrophages
- May have psammoma bodie

Papillary renal cell carcinoma

#MICROSCOPIC

#Diagnosis 👉🏻 Papillary renal cell carcinoma


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Papillary
بسبب القطع بين وكانها microcytic

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Foamy macrophages

#MICROSCOPIC

#Diagnosis 👉🏻 Papillary renal cell carcinoma


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Psammoma bodie
وعشان تشبه glomerular قال عنها glomeruloid pattern

#MICROSCOPIC

#Diagnosis 👉🏻 Chromophobe renal cell carcinoma


#The_microscopic_features
- cells polymorphisme 
- hyperchrmatic nucleus
- Cytoplasm clear (scantl

#GROSS

#Diagnosis 👉🏻 Wilms tumor ( Nephroblastoma )


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Tumor

✫ Gross description
- Tan yellow , soft
- lobulated

#MICROSCOPIC

#Diagnosis 👉🏻 Wilms tumor ( Nephroblastoma )

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Tubules

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Blastema

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Stroma

#The_microscopic_features
- Undifferentiated blastema
ويلي تكون spindle shape and hyperchromatic  
- Tubules
- Stroma

#MICROSCOPIC

#Diagnosis 👉🏻 Wilms tumor ( Nephroblastoma )

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Tubules

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Blastema

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Stroma

#MICROSCOPIC

#Diagnosis 👉🏻 Wilms tumor ( Nephroblastoma )


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Tubules

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Blastema

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Stroma

THE SECOND LAB DONE  ✓✓

#MICROSCOPIC

#Diagnosis → Koilocytosis

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Clear zone

#Features
Hyperchromatic
Pleomorphism
Clear zone around the nucleus

#MICROSCOPIC

#Diagnosis → Penile intraepithelial neoplasia

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Parakeratosis

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Papillomatosis (finger-like)

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Acanthosis

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Koilocytosis

#MICROSCOPIC

#Diagnosis → Penile intraepithelial neoplasia

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Parakeratosis

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Keratosis

#MICROSCOPIC

#Diagnosis → well differentiated squamous cell carcinoma (grade 1)

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Keratin pearls

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Nest of squamous cells with eosinophilic cytoplasm

#Most_commen_cause
HPV

#MICROSCOPIC

#Diagnosis → moderate differentiated SCC (grade 2)

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Keratin pearls

#Features
Nuclear atypia
Nuclear pleomorphism
Irregular nuclear membrane
It has keratin pearls less than SCC grade 1

#MICROSCOPIC

#Diagnosis → poor differentiated SCC (grade 3)

#Features
Distributed cells
Nuclear atypia
Nuclear pleomorphism
NO KERATIN PEARLS
NO SQUAMOUS NESTS

NORMAL TESTS

NORMAL TESTS

#GROSS

#Diagnosis → testicular TB


Caseous necrosis has cheese-like appearance

#MICROSCOPIC

#Diagnosis → testicular TB

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Hematogenous area with less nucleus

#GROSS

#Diagnosis → cryptorchidism

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Atropic
Pale white in color