#MICROSCOPIC

#Diagnosis 👉🏻  Malignant nephrosclerosis


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Fibrinoid necrosis

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Thrombosis

#MICROSCOPIC

#Diagnosis 👉🏻  Malignant nephrosclerosis


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Onion skin

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Tiny lumen

CYSTIC DISEASES OF THE KIDNEYS
fluid-filled sacs, to form in or around the kidneys.

Types
- Non genetic (simple kidney cyst)
- Genetic (polycystic kidney disease)


𑁍 Simple kidney cyst
• Very common.
• Benign.

The causes
Unknown

✫ Gross description
- Solitary cyst with thin wall and filled with clear yellow fluid.
- Usually unilocular.

✫Microscopic description
- simple epithelium lining without atypia
- may have clear cells (Do not have clear cells within the wall of the cyst)
- Papillary progactions



𑁍 Polycystic kidney disease
May caused compressione on blood vessels , ischemia, necrosis.

✫ Gross description
- large kidney
- Multiples cyst with clear or hemorrhage fluid

✫Microscopic description
- Cysts are lined by cuboidal or flattened
- Surrounded by collagenous stroma
- The interstitium showed fibrosis and in some areas mononucelar inflammatory infiltrate.
- thyroidisation

POLYCYSTIC KIDNEY

#MICROSCOPIC

#Diagnosis 👉🏻  Polycystic kidney  


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Cyst

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inflammatory cells infiltrate

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Glomerular

RENAL CELL CARCINOMA
(CLEAR CELLS CARCINOMA)
Invasive to pelvic and calyces , so caused hematuria

✫ Gross description
- Well circumscribed and unencapsulated
- cut surface
Solid , golden yellow, area of hemorrhage

✫Microscopic description
- cells polymorphisme
- hyperchrmatic nucleus (central)
- Cytoplasm clear (low nuclear cytoplasmic ratio)
- prominent nucleoli
- hemorrhage
- Nests of tumor cells

#GROSS

#Diagnosis 👉🏻 Clear cell carcinoma

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Hemorrhage

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Tumor

#MICROSCOPIC

#Diagnosis 👉🏻 Clear cell carcenoma


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Hemorrhage

باقي العلامات موضحة داخل السلايد

#MICROSCOPIC

#Diagnosis 👉🏻 Clear cell carcinoma


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Hemorrhage

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Nest of tumor cells

PAPILLARY RENAL CELL CARCINOMA


✫ Gross description
- Well circumscribed with pseudo capsule
- Tan yellow to red brown
- hemorrhage
- Necrosis
- Aries from cells of renal tubules

✫Microscopic description
- Small cuboidal cells arranged on single layer on papillary cores
- Cells are small with uniform
- Scant pale (not clear) cytoplasm
- hyperchromatic nuclei without nucleoli
- Papillary cores often contain foamy macrophages
- May have psammoma bodie

Papillary renal cell carcinoma