#Gross

#Diagnosis 👉🏻  Phenochromocytoma
"chromaffin reaction"


#The_red_arrow
tumor which has not been placed in dichromate fixative

#The_white_arrow
tumor at the bottom has been placed into a dichromate fixative
والذي يظهر لنا باللون البني الغامق وذلك عشان انه catecholamines حصلها oxidized

#Microscopic

#Diagnosis 👉🏻   Phenochromocytoma


#The_black_star
Neoplasm

#The_black_arrows
intervening capillaries

#The_blue_arrow
sustentacular cells

#The_red_area
Zellballen ( nest )

#The_yellow_arrows
Vacuoles

#The_blue_star
Normal adrenal


#The_features
- Nested (zellballen) with adjacent smaller sustentacular cells surrounded by abundant intervening capillaries
- Cells: large, polygonal to spindle , uniform or extensively vacuolated
- Cytoplasm: abundant fine, granular red-purple cytoplasm
- Nuclei: central round to oval, nucleoli prominent

سلايد اوضح

Microscopic

#Diagnosis 👉🏻   Phenochromocytoma


#The_yellow_arrows
intervening capillaries

#The_black_arrows
sustentacular cells

#The_blue_area
Zellballen ( nest )

#Microscopic

#Diagnosis 👉🏻  Phenochromocytoma


#The_black_arrow
Phenochromocytoma
والتي تظهر باللون البني عند صبغها بصبغة S100 لانه ذي الصبغة تصبغ الادرينالين و النورادرينالين ويلي يكونوا في حاله افراز بشكل كبير

#The_blue_arrow
Adrenal cortex (negative)

#Microscopic

#Diagnosis 👉🏻  Phenochromocytoma


#The_black_arrow
Phenochromocytoma
والتي تظهر باللون البني عند صبغها بصبغة Chromogranin
وتظهر الانوية باللون الازرق

#The_blue_arrow
Adrenal cortex (negative)

THE FIRST & SECOND LAB DONE  ✓✓

Q1)

Q2)

Q3)

Q4)

Q5)

Q6)

Q7)