KR20210028062A Physiological Saline Containing Graphene

https://worldwide.espacenet.com/patent/search/family/075143365/publication/KR20210028062A?q=pn%3DKR20210028062A

here you can download the safety Data Sheet for ALC-0135.

“Poly(ethylene glycol) (PEG), also known as poly(ethylene oxide) (PEO), is an amphiphilic polyether that is soluble both in water and most organic solvents. PEG and its derivatives are among the few polymers approved for medical uses by the FDA.

Functionalized PEG, also named activated PEG, is a family of PEG derivatives decorated with functional groups. Funtionalized PEGs are used broadly for drug PEGylation, polymer engineering, nantechnology, biotechnology, and biomedical engineering.”

This is the description given by Sinopeg, Chinese company that delivers PEGs for most Covid injection manufacturers.

From their September 2020 blog post we extract more details:

“The coupling of PEG to protein is also called protein polyglycolization, which is essentially a drug delivery technology. The coupling of activated peg with protein molecules can improve the three-dimensional space state of proteins, resulting in changes in various biochemical properties of proteins. For example, chemical stability increased, half-life prolonged, immunogenicity and toxicity decreased or disappeared, protein solubility increased. SINOPEG is a dynamic science company dedicated to drug delivery systems (DDS). SINOPEG are specialized in the R&D of long acting biopharmaceuticals, developing and manufacturing of block copolymers, lipids for drug delivery, medical devices, bio-engineering, and other broad uses.

Up to now, the FDA has approved 20 polyglycolic drugs. In addition to monoclonal antibodies, polyglycolic drugs have become the most powerful drug development technology.

As a leading company in polyethylene glycol derivatives (PEGs)， SINOPEG is capable of supplying small to large quantities of rich selection of PEG derivative products with unique molecular designs (chemical structure, molecular weights (MW)) and exceptional product quality control to serve bio-technology and pharmaceutical companies and research organizations worldwide.”

Facilitation of Polymerase Chain Reaction with Poly(ethylene glycol)-Engrafted Graphene Oxide Analogous to a Single-Stranded-DNA Binding Protein [source]

Method and process to make and use cotton-tipped electrochemical immunosensor for the detection of corona virus United States Patent 11035817

https://www.freepatentsonline.com/11035817.html

Mechanism of DNA Adsorption and Desorption on Graphene Oxide

https://pubs.acs.org/doi/full/10.1021/la503401d