SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro

This paper is showing that the (S) protein is inhibiting the DNA damage repair mechanisms. There are genetic predispositions to certain types of cancers, and certain cancers are due to DNA repair mechanism problems.

This is basically saying that DNA repair inhibition from the (S) protein leads to AIDS-like syndrome. AIDS-like syndrome means that there is an opportunistic infection that happens, especially in cancers, due to the downregulation of the immune system.

Cancer Route:
SARS-CoV-2 (S) protein ends up getting into the nucleus of your cells (the nucleus has pores called nucleopores). This is happening in high infection cases when human LINE-1 is expressed and this creates a higher chance of integration. Once integrated, the (S) protein inhibits the repair mechanism in the nucleus when DNA gets damaged. So, you'll have breaks in the DNA or misread/misdirected DNA code put in, and as it divides it starts to drift and this is where cancers arise.

So, if you don't have repair mechanisms in place, one line of problems is cancers, another issue is genetic disorders because when the cells are dividing it cannot repair them during the division process.

There is Gain-of-Function (GoF) and Loss-of-Function (LoF; the inability of something to work). A lot of genetic disorders/cancers happen due to LoF. LoF can happen due to a single nucleotide polymorphism (SNP) and loss of heterozygosity (LOH).

See: Gene Knockout & two-hit hypothesis

SNP/MNP changes the actual code and causes disease. Normally these are tumor suppressor genes, like P53, Wnt pathway, and BRCA1, for example, but if you don't have a repair mechanism working, when these cells are multiplying they will make mistakes and will have a loss of heterozygosity, resulting in the creation of cancers. see this paper: S2 Subunit of SARS-nCoV-2 Interacts with Tumor Suppressor Protein p53 and BRCA: an In Silico Study

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AIDS-like Syndrome Route:
The repair mechanism is very important in T and B-cells.

Antibodies created by T and B-cells are created by different types of code and recombined. To make this, there is something called the heavy chain; the heavy chain becomes the D-J segment, which turns into something smaller that then turns into the V-D-J segment. That turns into the actual code that will eventually make the protein. This turns into the transcription segment and it will then translate into becoming a protein and assemble.

Light chain and heavy chain. Two pieces to the heavy chain, two pieces to the light chain. Variable piece and the constant piece.

The light piece is made of L-V-J-C on your germline DNA. There are spaces between, it goes through a process and is rearranged and joined where that space is cut out. So it’s just L-VJ-C that is recombining inside of your cell. When it’s cutting/pasting, this is part of the repair mechanism. This turns into RNA. Then what happens is L-VJ-C-AAAA goes through a splicing where the space between the J and the C is taken out and it still has the poly(A). So, it will look like L-VJC-AAAAA with a poly(A) tail.

B-cells have isotype switching. B-cells can have a certain type of antibody and then switch to a new type of antibody. This switching happens through a signal, and that signal then, in its nucleus, begins to do the aforementioned recombination mechanisms. If it cannot do all of the recombination because the DNA repair is not working, then the switching mechanism doesn’t happen, so you have lower concentrations of all of the antibodies. Up front, if certain cells are infected and are unable to create the antibody because it’s not recombining, and the ones that are already there cannot switch due to SARS-CoV-2, then you cannot go from IgM to IgA or IgG, for example, so the switching slows down and over time you start to lose your antibodies.

In short, disruption of DNA repair mechanisms leads to opportunistic infections, cancers, AIDS-like syndrome.

Polyphenolics Evoke Healing Responses: Clinical Evidence and Role of Predictive Biomarkers

"Oxidative stress from free radical damage is increasingly associated with the development and progression of chronic, degenerative, and autoimmune diseases. Oxygen radical absorbance capacity (ORAC) and total oxyradical scavenging capacity (TOSC) assays have been developed to measure antioxidant capacity in foods. A high ORAC value indicates increased activity against free radicals and subsequent reduction in reactive oxygen species (ROS) due to high antioxidant content. Both assays are useful in identifying phytochemicals with high antioxidant activity."

"Quercetin possesses anticancer properties in part by enhanced degradation of NF-kappa B consistent with a down-regulation of the NF-kappa B binding activity. This activates the AP-1/JNK pathway, important in apoptosis."

https://sci-hub.se/10.1016/B978-0-12-813006-3.00029-5

COVID shots are the deadliest 'vaccines' in medical history

In this interview, Steve Kirsch, executive director of the COVID-19 Early Treatment Fund, reviews some of the COVID-19 'vaccine' data he’s presented to the U.S. Food and Drug Administration and the Centers for Disease Control and Prevention during various meetings.

[source]

Civil disobedience works! The system can't handle more than 100K protestors (in Australia)

The only way out is non-compliance en masse...

Twice as many cardiac arrests in athletes this year vs all history (YouTube censored)

A brief overview of the plethora of sudden cardiac arrests caused by the recent 'vaccine' rollout amongst athletes....

Walk Them to Their Death

Dr. Robert Duncan - Cybernetics: Intelligent Systems of Control

Wiltshire, England, 2015

[source]

Differences in Vaccine and SARS-CoV-2 Replication Derived mRNA: Implications for Cell Biology and Future Disease

"Expression of chimeric spike-human peptides may be unique to pseudouracil based mRNA vaccination and raises concerns over immune de-regulation including autoimmunity that may develop with such chimeric inoculations."

"With any virus or vaccine that enables latent virus reactivation we must consider the case of viral recombination. Chimeric RNAs are more likely to form with mRNAs that have degenerate bases. In this hypothetical case, a non-replicative pseudouridylated mRNA may hitchhike into a replication form via recombination with a live virus."

"Retroviral and non-retroviral RNA sequences are abundantly integrated into mammalian DNA. These inserted viral sequences exist in the form of long interspersed nuclear elements (LINEs). These LINE based retrotransposons mobilize and also transcribe human DNA not associated with the LINE sequences forming pseudogenes. These can be active in disease onset including tumorigenesis...the polio RNA sequences are identified with a 100% sequence homology to human chromosomes and are associated with cancer progression."

"...pseudouridylations of mRNAs are subject to activity of PUS7 writer protein which is a key regulator of protein translation and determinant of stem cell growth and differentiation. Dysregulation of PUS7 activity correlates with agitated protein synthesis in stem cells which leads to hematological disorders and aggressive stem cell acute myeloid leukemia."

"The conclusions of Ahanotu et al. are prescient and suggest the most likely method for delivering SEB as a bioweapon would be through the use of an aerosol.

The use of SEB as a weapon of mass casualty is considered likely for several reasons, mainly high morbidity with ease of production and dispersion, the delayed onset of disease symptoms associated with high morbidity and low mortality and difficulty in diagnosis. Staphylococcal enterotoxin B is a superantigen capable of massive non-specific activation of the immune system. Because of the remarkable toxicity and stability, they would most likely be disseminated as an aerosol”

note: see comment section for additional resources + full paper here

https://nobulart.com/covid-19-vaccine-ingredients/

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HCG Found in WHO Tetanus Vaccine in Kenya Raises Concern in the Developing World

from the Abstract:

"In 1993, WHO announced a “birth-control vaccine” for “family planning”. Published research shows that by 1976 WHO researchers had conjugated tetanus toxoid (TT) with human chorionic gonadotropin (hCG) producing a “birth-control” vaccine.

Conjugating TT with hCG causes pregnancy hormones to be attacked by the immune system. Expected results are abortions in females already pregnant and/or infertility in recipients not yet impregnated. Repeated inoculations prolong infertility. Currently WHO researchers are working on more potent anti-fertility vaccines using recombinant DNA. WHO publications show a long-range purpose to reduce population growth in unstable “less developed countries”.

By November 1993 Catholic publications appeared saying an abortifacient vaccine was being used as a tetanus prophylactic. In November 2014, the Catholic Church asserted that such a program was underway in Kenya. Three independent Nairobi accredited biochemistry laboratories tested samples from vials of the WHO tetanus vaccine being used in March 2014 and found hCG where none should be present. In October 2014, 6 additional vials were obtained by Catholic doctors and were tested in 6 accredited laboratories.

Again, hCG was found in half the samples. Subsequently, Nairobi’s AgriQ Quest laboratory, in two sets of analyses, again found hCG in the same vaccine vials that tested positive earlier but found no hCG in 52 samples alleged by the WHO to be vials of the vaccine used in the Kenya campaign 40 with the same identifying batch numbers as the vials that tested positive for hCG. Given that hCG was found in at least half the WHO vaccine samples known by the doctors involved in administering the vaccines"

https://www.scirp.org/journal/paperinformation.aspx?paperid=81838

[archive]