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Can a frontline doctor and his patient gain confidence that Ivermectin is working for long haulers before large randomized trials?

Yes.

Via a process called
Challenge-Dechallenge-Rechallenge:

A pharmacist should not second-guess and obstruct such a classic, pragmatic approach to medicine.
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Legendary but Chilling Depiction of the 2020's Got Judge Napolitano Fired from Fox in 2011
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Vaccination Mandates & Passports Get Surprise Blast from the EU Parliament

Reacting to the increased violations of basic human rights all across EU, members of the European Parliament took a common stand in defense of the fundamental rights of all EU citizens, which are under threat now due to mandatory vaccination and abusive use of the Digital COVID Certificate.

Speaking at a press conference in Strasbourg, on October 20, 2021, they also gave voice to the severe concerns of hundreds of staff members working for the European Parliament, who live under threat of losing their jobs if they do not have the Digital COVID Certificate, aka Green Certificate.

The press conference called “Defending fundamental rights by opposing the misuse of Digital Green Certificate” was addressed by four MEPs: Christine Anderson (Germany, ID), Francesca Donato (Italy, NI), Ivan Vilibor Sinčić (NI, HR) and Cristian Terheş (ECR, RO).
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The Rothschilds, The Queen and The Military Biotech Complex: 150 Years of Common History

note: see comment section for synopsis and additional resources
“This is to request that the current retention allowance [(b)(6) redaction] for Dr. Anthony S. Fauci be converted to a permanent pay adjustment in the amount [(b)(6) redaction] over his base pay of [(b)(6) redaction] in order to appropriately compensate him for the level of responsibility in his current position of Director, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), especially as it relates to his work on biodefense research activities.” -GW Bush
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NIH Fear Factory: Taxpayer-Funded Monkey Experiments Revealed

A White Coat Waste Project lawsuit and investigation revealed that the NIH spent $16 million to give monkeys brain damage and scare them with fake snakes and spiders.

Monkeys had parts of their brains destroyed with acid in order to increase their capacity for terror, and were then tormented with simulated spiders, snakes and other things they instinctively fear. These experiments have been ongoing for more than four decades.
Melatonin-Index as a biomarker for predicting the distribution of presymptomatic and asymptomatic SARS-CoV-2 carriers

Lung melatonin modulates SARS-CoV-2 infection

http://www.melatonin-research.net/index.php/MR/article/view/109
Low melatonin as a contributor to SARS-CoV-2 disease

http://www.melatonin-research.net/index.php/MR/article/view/114
The potential of melatonin in the prevention and attenuation of oxidative hemolysis and myocardial injury from cd147 SARS-CoV-2 spike protein receptor binding

http://www.melatonin-research.net/index.php/MR/article/view/86
The Effect of Melatonin on Thrombosis, Sepsis and Mortality Rate in COVID-19 Patients

https://www.sciencedirect.com/science/article/pii/S1201971221007980
Reply to CDC Re: Natural Immunity v. Vaccine Immunity

https://www.icandecide.org/wp-content/uploads/2021/10/Reply-to-CDC-Re-Natural-Immunity-v-Vaccine-Immunity.pdf

The exchange, while long, is definitely worth the read. In short – and this is going to be an understatement – the CDC fails to rebut the clear, consistent, and irrefutable science demonstrating the superiority of natural immunity compared to vaccine immunity. In summary:

• Who is more likely to get Covid-19 (the symptomatic disease)? The answer is clear. Natural immunity provides greater than 99% protection against Covid-19 while vaccine immunity is well below this level of protection even directly after vaccination and from there rapidly wanes.

• Who is more likely to become infected with and transmit the virus (with or without symptoms)? The answer is again crystal clear. Vaccine immunity does not prevent infection and transmission, while natural immunity does. As the Director of the CDC explained, the vaccinated need to wear masks because, “what [the COVID-19 vaccines] can’t do anymore is prevent transmission.”  (This point is also covered in a prior article.)

• Worse, based on official government data from the UK and Israel, the known adverse events from COVID-19 vaccine exceed the known benefits of vaccinating the naturally immune.
OSINT pinned «https://docs.google.com/document/d/1AD0lL3Rm4lDExo4q7McBxeeHOqO8bCWWerlGu7YJubQ/edit»
OSINT
cognitive-warfare-nato.pdf
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Clark Scholar Cognitive Warfare

This project was intended to define and identify cognitive warfare campaigns, in order to protect NATO and its allies. A solution, a dashboard which visualizes campaigns and tracks cognitive attacks, is currently being developed. This effort was made in cooperation between Johns Hopkins University, Imperial College London, and the Czech Technical University.

[source]