Which of the following is a potential side effect of alkylating agents?
Anonymous Quiz
7%
Enhanced repair enzyme activity
29%
Inhibition of DNA synthesis
18%
Exclusively mutagenic effects
45%
Reactivity with other biomolecules
The anthracycline antibiotics are characterized by ______ anthracene nucleus
Anonymous Quiz
14%
planar nonoxidized
8%
spherical oxidized
72%
planar oxidized
6%
spherical nonoxidized
what is the mechanism of
anthracycline?
..by exhibit their cytotoxic effects initially focused on the ability of the compounds to associate with DNA resulting from intercalation of their planar ring system reinforced by auxiliary binding of the amino sugar.
anthracycline?
..by exhibit their cytotoxic effects initially focused on the ability of the compounds to associate with DNA resulting from intercalation of their planar ring system reinforced by auxiliary binding of the amino sugar.
Several anthracyclines are used clinically such as
Anonymous Quiz
25%
inhibitor of microtubule function
62%
doxorubicin ,daunorubicin
13%
oxidized anthracene nucleus
👍1
the anthracyclines are considered specific for the R phase of the cell cycle.
Anonymous Quiz
36%
true
64%
false
derivatives of podophyllotoxin functions as an inhibitor of microtubule function.
Anonymous Quiz
25%
Bleomycin
13%
Anthracyclines
62%
Epipodophyllotoxins
Bleomycin can cause a pulmonary toxicity, which may first occur as pneumonitis
Anonymous Quiz
87%
true
13%
false
What strategy was employed in the development of cyclophosphamide and ifosfamide to improve selectivity a control aziridinium cation formation?
Anonymous Quiz
12%
Addition of electron-donating functionalities.
25%
Attachment of nitrogen to a phenyl ring
59%
Utilization of highly electron-withdrawing functionalities
5%
Stabilization of the aziridinium cation
🗿5
- الرساله ؛ ملخص ادوية كيمياء لحد ادوية بيورين من اكمل ادزهم
🙏2
The enzyme responsible for this conversion of bleomycin is known as
Anonymous Quiz
54%
bleomycin hydrolase
25%
bleomycin carboxylase
20%
bleomycin kinase
✨طريقك نحو الرسوب✨
¹⁶﴿ وقُل رَبِّ ارحَمهُما كَما رَبَّياني صَغيرًا ﴾
¹⁷﴿أُجِيبُ دَعْوَةَ الدَّاعِ إِذَا دَعَانِ﴾
🙏9❤5💘1