43. What is the primary mechanism of action of probenecid in promoting renal clearance of uric acid?
Anonymous Quiz
5%
a. Blocking prostaglandin synthesis
12%
b. Inhibiting xanthine oxidase
18%
c. Enhancing uric acid reabsorption
26%
d. Converting uric acid to allantoin
40%
e. Inhibiting urate-anion exchanger
44. At what creatinine clearance level should probenecid be avoided?
Anonymous Quiz
15%
a. Less than 30 mL/min
68%
b. Less than 50 mL/min
8%
c. Greater than 70 mL/min
7%
d. Less than 20 mL/min
2%
e. No restrictions on creatinine clearance
45. What is the primary function of pegloticase in patients with gout?
Anonymous Quiz
7%
a. Inhibiting xanthine oxidase
9%
b. Blocking prostaglandin synthesis
69%
c. Converting uric acid to allantoin
11%
d. Inhibiting urate-anion exchanger
4%
e. Enhancing uric acid reabsorption
46. How often is pegloticase administered in patients with gout?
Anonymous Quiz
6%
a. Every week
63%
b. Every 2 weeks
17%
c. Once a month
7%
d. Twice a month
6%
e. Every 3 weeks
47. What adverse reactions may occur with pegloticase, requiring premedication with antihistamines and corticosteroids?
Anonymous Quiz
7%
a. Nausea and vomiting
24%
b. Dermatologic reactions
16%
c. Anemia and anaphylaxis
49%
d. Infusion-related reactions
5%
e. Hypertension and headache
اذا اشتدت بيكم ف اختاروا B لأن الواضح محبوبه عند الدكتور
😁5
✨طريقك نحو الرسوب✨
¹¹﴿ إِنِّي جَزَيْتُهُمُ الْيَوْمَ بِمَا صَبَرُوا أَنَّهُمْ هُمُ الْفَائِزُونَ ﴾
¹²"وُجُوهٞ يَوۡمَئِذٖ نَّاعِمَةٞ ٨
لِّسَعۡيِهَا رَاضِيَةٞ ٩
لِّسَعۡيِهَا رَاضِيَةٞ ٩
ان شاءالله نرجس صلاح وطلاب اوروك يجاوبون الأحد آمين 🫶🏻🩵
🙏7
⏳MCQs Pharma Lec4⏳
•Drugs affecting bone metabolism
⚠️اسئلة الكوز⚠️
•Drugs affecting bone metabolism
⚠️اسئلة الكوز⚠️
1. What is the primary characteristic of Osteoporosis?
Anonymous Quiz
5%
a. Excessive bone formation
91%
b. Progressive loss of bone mass
2%
c. Enlarged or misshapen bones
2%
d. Softening of bones
0%
e. Increased calcium homeostasis
2. In which population does Osteoporosis occur most frequently?
Anonymous Quiz
2%
a. Children
93%
b. Postmenopausal women
2%
c. Teenagers
2%
d. Middle-aged men
0%
e. Infants
3. Which disorder is usually limited to one or a few bones?
Anonymous Quiz
6%
a. Osteoporosis
8%
b. Osteomalacia
78%
c. Paget disease
4%
d. Rickets
3%
e. Bone remodeling disorder
4. What is Osteomalacia often attributed to?
Anonymous Quiz
2%
a. Vitamin C deficiency
2%
b. Vitamin A deficiency
90%
c. Vitamin D deficiency
6%
d. Calcium deficiency
1%
e. Iron deficiency
5. What cells are responsible for bone resorption in the remodeling process?
Anonymous Quiz
15%
a. Osteoblasts
9%
b. Hydroxyapatite crystals
66%
c. Osteoclasts
7%
d. Calcium phosphate crystals
3%
e. Bone-building cells
👍1
6. Which strategy is NOT mentioned for reducing bone loss in postmenopausal women?
Anonymous Quiz
5%
a. Adequate dietary intake of calcium
5%
b. Weight-bearing exercise
5%
c. Smoking cessation
10%
d. Excessive alcohol intake
75%
e. Regular caffeine intake