⭕️18. Serotonin syndrome is a result of:
Anonymous Quiz
1%
a) Increased stores of monoamine
5%
b) Significant accumulation of amine neurotransmitters in the synapses
93%
c) Both a and b
0%
d) Depleted stores of biogenic amines
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⭕️19. The therapeutic response to antidepressant drugs is usually over a period of:
Anonymous Quiz
6%
a) 2-3 days
92%
b) 2-3 weeks
1%
c) 24 hours
1%
d) 2-3 month
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⭕️20. Which of the following antidepressants may have latency period as short as 48 hours?
Anonymous Quiz
71%
a) Tranylcypromine
6%
b) Imipramine
12%
c) Fluoxetine
11%
d) Amitrityline
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⭕️21. Which of the following features do MAO inhibitors and tricyclic antidepressants have in common?
Anonymous Quiz
6%
a) Act postsynaptically to produce their effect
18%
b) Can precipitate hypotensive crises if certain foods are ingested
75%
c) Increase levels of biogenic amines
1%
d) Are useful for the manic phase of bipolar disorder
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⭕️22. Tricyclic antidepressants are:
Anonymous Quiz
4%
a) Highly selective serotonin reuptake inhibitors
4%
b) Monoamine oxidase inhibitors
6%
c) Selective norepinephrine reuptake inhibitors
87%
d) Mixed norepinephrine and serotonin reuptake inhibitors
⭕️23. Which of the following autonomic nervous system effects is common for tricyclic antidepressants?
Anonymous Quiz
3%
a) Antimuscarinic action
1%
b) Antihistaminic action
2%
c) Alfa adrenoreceptor-blocking action
94%
d) All of the above
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⭕️24. Indicate an effective antidepressant with minimal autonomic toxicity:
Anonymous Quiz
12%
a) Amitrityline
81%
b) Fluoxetine
4%
c) Imipramine
3%
d) Doxepin
⭕️25. Fluoxetine has fewer adverse effects because of:
Anonymous Quiz
1%
a) Mixed norepinephrine and serotonin reuptake inhibition
3%
b) Depleted stores of amine neurotransmitters
45%
c) Minimal binding to cholinergic, histaminic, and alfa-adrenergic receptors
51%
d) All of the above
⭕️26. Which of the following tricyclic and heterocyclic antidepressants has the greatest sedation?
Anonymous Quiz
2%
a) Doxepin
23%
b) Amitriptyline
2%
c) Trazodone
72%
d) All of the above
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⭕️27. Which of the following tricyclic and heterocyclic agents has the least sedation?
Anonymous Quiz
54%
a) Protriptyline
4%
b) Trazodone
34%
c) Amitriptyline
9%
d) Mitrazapine
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⭕️28. Indicate a tricyclic or a heterocyclic antidepressant having greatest antimuscarinic effects:
Anonymous Quiz
3%
a) Desipramine
82%
b) Amitriptyline
4%
c) Trazodone
10%
d) Mirtazapine
⭕️29. Indicate a tricyclic or a heterocyclic antidepressant having least antimuscarinic effects:
Anonymous Quiz
4%
a) Trazodone
3%
b) Buprorion
9%
c) Mirtazapine
85%
d) All of the above
⭕️30. Which of the following antidepressants has significant alfa2-adrenoreceptor antagonism?
Anonymous Quiz
15%
a) Amitriptyline
20%
b) Nefazodone
64%
c) Mirtazapine
1%
d) Doxepin
⭕️31. Indicate the main claim for an ideal antidepressant agent:
Anonymous Quiz
1%
a) A faster onset of action
0%
b) Fewer adverse sedative and autonomic effects
2%
c) Fewer toxicity when overdoses are taken
98%
d) All of the above
⭕️32. Sedation, peripheral atropine-like toxicity (e.g. Cycloplegia, tachycardia, urinary retention, and constipation), orthostatic
hypotension, arrhythmias, weight gain and sexual disturbances are possible adverse effects of:
hypotension, arrhythmias, weight gain and sexual disturbances are possible adverse effects of:
Anonymous Quiz
5%
a) Sertaline
90%
b) Amitriptyline
3%
c) Phenelsine
2%
d) Bupropion
⭕️33. Which of the following drugs is least likely to be prescribed to patients with prostatic hypertrophy, glaucoma, coronary
and cerebrovascular disease?
and cerebrovascular disease?
Anonymous Quiz
75%
a) Amitriptyline
5%
b) Paroxetine
5%
c) Bupropion
15%
d) Fluoxetine
⭕️34. Indicate the antidepressant agent, which is a phenyltolylpropylamine derivative:
Anonymous Quiz
7%
a) Paroxetine
8%
b) Maprotiline
74%
c) Fluoxetine
11%
d) Amitriptyline
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⭕️35. The mechanism of fluoxetine action includes:
Anonymous Quiz
3%
a) Selective inhibition of serotonine uptake in the CNS
0%
b) Little effect on central norepinephrine or dopamine function
30%
c) Minimal binding to cholinergic, histaminic, and alfa-adrenergic receptors
67%
d) All of the above
⭕️36. Which of the following antidepressants is used for treatment of eating disorders, especially buliemia?
Anonymous Quiz
12%
a) Amitriptyline
70%
b) Fluoxetine
9%
c) Imipramine
9%
d) Tranylcypromine
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⭕️37. A highly selective serotonine reuptake inhibitor is:
Anonymous Quiz
3%
a) Sertaline
1%
b) Paroxetine
13%
c) Fluoxetine
84%
d) All of the above
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