⭕️62. Indicate the mechanism of barbiturate action (at hypnotic doses):
Anonymous Quiz
81%
a) Increasing the duration of the GABA-gated Cl- channel openings
1%
b) Directly activating the chloride channels
3%
c) Increasing the frequency of Cl- channel opening events
15%
d) All of the above
👏1
⭕️63. Which of the following hypnotic agents is a positive allosteric modulator of GABAA receptor function?
Anonymous Quiz
3%
a) Zaleplon
1%
b) Flurazepam
5%
c) Zolpidem
90%
d) All of the above
⭕️65. Which of the following hypnotic agents is able to interact with both BZ1 and BZ2 receptor subtypes?
Anonymous Quiz
4%
a) Zaleplon
3%
b) Phenobarbital
86%
c) Flurazepam
7%
d) Zolpidem
⭕️66. Flumazenil blocks the actions of:
Anonymous Quiz
7%
a) Phenobarbital
3%
b) Morphine
90%
c) Zolpidem
0%
d) Ethanol
👏1
⭕️67. Which of the following agents blocks the chloride channel directly?
Anonymous Quiz
1%
a) Secobarbital
8%
b) Flumazenil
7%
c) Zaleplon
84%
d) Picrotoxin
⭕️69. Indicate the main claim for an ideal hypnotic agent:
Anonymous Quiz
3%
a) Rapid onset and sufficient duration of action
1%
b) Minor effects on sleep patterns
2%
c) Minimal “hangover” effects
84%
d) All of the above
10%
e) None of the above
👏1
⭕️70. Indicate the hypnotic drug, which binds selectively to the BZ1 receptor subtype, facilitating GABAergic inhibition:
Anonymous Quiz
4%
a) Thiopental
82%
b) Zolpidem
10%
c) Flurazepam
4%
d) Phenobarbital
⭕️71. Which agent exerts hypnotic activity with minimal muscle relaxing and anticonvulsant effects?
Anonymous Quiz
12%
a) Flurazepam
16%
b) Triazolam
71%
c) Zaleplon
1%
d) None of the above
⭕️72. Indicate the usual cause of death due to overdose of hypnotics:
Anonymous Quiz
97%
a) Depression of the medullar respiratory center
1%
b) Hypothermia
1%
c) Cerebral edema
1%
d) Status epilepticus
👏1
⭕️73. Choose the drug that has been found to be more selective for the ω1 subtype of BZD receptor, and produces hypnotic action but little antianxiety, muscle relaxant or anticonvulsant actions:
Anonymous Quiz
6%
A. Zopiclone
74%
B. Zolpidem
16%
C. Flumazenil
4%
D. Melatonin
⭕️74. Diazepam is indicated in the following conditions except:
Anonymous Quiz
87%
A. Generalized tonic-clonic (grand mal) epilepsy
5%
B. Tetanus
1%
C. Febrile convulsions
6%
D. Cardiac catheterization
👏1
⭕️75. The following drug is used to reverse the CNS depression produced by diazepam:
Anonymous Quiz
13%
A. Dexamphetamine
3%
B. Doxapram
8%
C. Physostigmine
77%
D. Flumazenil
⭕️1. The state of “general anesthesia” usually includes:
Anonymous Quiz
1%
a) Analgesia
8%
b) Loss of consciousness, inhibition of sensory and autonomic reflexes
1%
c) Amnesia
91%
d) All of the above
❤1👏1
⭕️2. Inhaled anesthetics and intravenous agents having general anesthetic properties:
Anonymous Quiz
88%
a) Directly activate GABAA receptors
3%
b) Facilitate GABA action but have no direct action on GABAA receptors
5%
c) Reduce the excitatory glutamatergic neurotransmission
4%
d) Increase the duration of opening of nicotine-activated potassium channels
👏2
⭕️3. Indicate the anesthetic, which is an inhibitor of NMDA glutamate receptors:
Anonymous Quiz
4%
a) Thiopental
6%
b) Halothane
88%
c) Ketamine
2%
d) Sevoflurane
👏1
⭕️4. An ideal anesthetic drug would:
Anonymous Quiz
1%
a) Induces anesthesia smoothly and rapidly and secure rapid recovery
0%
b) Posses a wide margin of safety
1%
c) Be devoid of adverse effects
99%
d) All of the above
👏1
⭕️5. Which of the following general anesthetics belongs to inhalants?
Anonymous Quiz
10%
a) Thiopental
76%
b) Desfluran
3%
c) Ketamine
11%
d) Propofol
⭕️6. Indicate the anesthetic, which is used intravenously:
Anonymous Quiz
83%
a) Propofol
6%
b) Halothane
4%
c) Desflurane
8%
d) Nitrous oxide
⭕️7. Which of the following inhalants is a gas anesthetic?
Anonymous Quiz
4%
a) Halothane
0%
b) Isoflurane
95%
c) Nitrous oxide
1%
d) Desflurane