⭕️1. A drug in the central nervous system is enhanced if the drug is
Anonymous Quiz
3%
(a) Ionized
14%
(b) More lipid soluble
2%
(c) Given intravenously
81%
(d) Highly plasma protein bound
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⭕️2. Following is GABAA agonist
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82%
(a) Muscimol
8%
(b) Baclofen
4%
(c) Bicuculline
3%
(d) None of the above
3%
(e) All of the above
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⭕️3. Which of the following is a neurotransmitter in the central nervous system (CNS)
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8%
(a) Acetylcholine
1%
(b) Noradrenaline
0%
(c) Dopamine
1%
(d) 5–Hydroxytryptamine
89%
(e) All of the above
⭕️4. The autonomic nervous system is also known as
Anonymous Quiz
1%
(a) Visceral
0%
(b) Vegetative
88%
(c) Involuntary nervous system
11%
(d) All of the above
⭕️5. Following is GABAB agonist
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8%
(a) Muscimol
83%
(b) Baclofen
1%
(c) Picrotoxin
8%
(d) Bicuculline
⭕️6. Following is GABAA antagonist:
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6%
(a) Muscimol
87%
(b) Bicuculline
1%
(c) Strychnine
5%
(d) Baclofen
⭕️7. The apparent stimulation of CNS by local anesthetic is due to
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5%
(a) Direct excitatory action
68%
(b) Depression of inhibitory neurons
1%
(c) Non specific action
26%
(d) All of the above
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⭕️8. Histamine induced edema results from the action on _____ receptors
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2%
(a) H3
3%
(b) H2
92%
(c) H1
3%
(d) All of the above
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⭕️9. Following is the effect of histamine on small vessels
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3%
(a) Outward passage of plasma protein and fluid into the extracellular spaces
4%
(b) Increase in the flow of lymph and its protein content
2%
(c) Formation of edema
92%
(d) All of the above
⭕️10. Which of the following is not a CNS depressant but increases the tendency to fall asleep at night ?
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1%
(a) Pyridoxine
1%
(b) Methaqualone
97%
(c) Melatonin
1%
(d) Ethanol
⭕️12. Which of the following neuromuscular blocking agent has short duration of action
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5%
(a) Atracurium
81%
(b) Mivacurium
11%
(c) Pancuronium
3%
(d) Doxacurium
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⭕️13. Botulinium toxin causes muscle palsy by blocking
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1%
(a) Nerve action potential
95%
(b) Acetylcholine release
2%
(c) Permeability to sodium and potassium
2%
(d) Muscle action potential
⭕️14. Neuromuscular blocking drugs do not produce central actions because
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3%
(a) Nicotinic receptors are not present in the brain
93%
(b) They do not cross the blood-brain barrier
2%
(c) They are sequestrated in the periphery by tight binding to the skeletal muscles
2%
(d) They do not ionize at the brain pH
⭕️15. Pancuronium differs from tubocurarine in that
Anonymous Quiz
2%
(a) It is a depolarizing blocker
2%
(b) Its action is not reversed by neostigmine
96%
(c) It can cause rise in BP on rapid I.V. injection
1%
(d) It causes marked histamine release
⭕️16. The drug that produces neuromuscular blockade by persistent epolarization is
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12%
(a) D-tubocurarine
2%
(b) Gallamine
11%
(c) Pancuronium
76%
(d) Decamethonium
⭕️17. Agents that block neuromuscular transmission of acetyl choline acts via
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2%
(a) Inhibiting acetyl choline synthesis
3%
(b) Inhibiting acetyl choline release
1%
(c) Inhibiting post-synaptic action of acetyl choline
95%
(d) All of the above
⭕️18. Which of the following drugs enhances GABA actions on the neuromuscular junctions of nematodes and arthropods?
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5%
(a) Glutamic acid
80%
(b) Ivermectin
10%
(c) Picrotoxin
2%
(d) Pyrantel pamoate
3%
(e) Pyrimethamine
⭕️19. The therapeutic use of neostigmine bromide is as a
Anonymous Quiz
2%
(a) Miotic
3%
(b) CNS depressant
92%
(c) Treatment of curare poisoning
2%
(d) Neuromuscular blocker
1%
(e) Muscle relaxan
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⭕️20. The organ extremely sensitive to the action of atropine is
Anonymous Quiz
3%
(a) Gastric glands
95%
(b) Salivary glands
1%
(c) Urinary bladder muscle
1%
(d) Heart
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⭕️21. The antimuscarinic agent preferred in the management of motion sickness is
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5%
(a) Atropine methonitrate
93%
(b) Scopolamine
0%
(c) Homatropine methyl bromide
2%
(d) Ipratropium bromide