The diffusion coefficient, D, is defined as the amount of a drug that diffuses across
a membrane of a given unit area per unit time when the concentration gradient is unity

The nature and quantity of the diluent, binder disintegrant, lubricant and any wetting agent are important in the formulation of capsule dosage form

In in vitro studies of dissolution kinetics, the agitation rate is about 50 rpm (revolutions per minute).

Tablet coatings may be used for several reasons; all are true except:

is an-----
example of protein peptide drug generally
not given orally due to degradation and inadequate absorption in GIT

As the plasma drug concentration decreases during elimination, the rate of
elimination dDE/dt will----accordingly, but the clearance will be-----

Physiological factors affecting drug absorption in the gastrointestinal tract
include

Solubilization of aspirin may be increased by the addition of

All are effects of food on the bioavailability *:of a drug from drug product except

Factors that affect drug dissolution of a :solid oral dosage form include

One of the following not related to the formulation factors that influence the *bioavailability of drug from capsule

which one will have more dissolution behavior in phoaphate buffer (pH
7.5):erythromycin dihydrate, monohydrate or anhydrate

Dissolution