the liver and adipose tissue, this leads to increased lipogenesis, and a high intake of fructose may be a factor in the development of obesity

Other tissues that normally derive much of their energy from glycolysis and produce lactate include

dephosphorylation that causes an increase in activity

Because of the dependence of the brain on glucose as a fuel, these metabolic defects commonly cause neurological disturbances

Dihydrolipoyl transacetylase

Inherited pyruvate kinase and aldolase deficiency in erythrocytes cause hemolytic anemia

Vitamin B1 deficiency is associated with impairment of glucose metabolism,
significant

Phosphofructokinase inhibited by citrate

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