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White noise improves learning by modulating activity in dopaminergic midbrain regions and right superior temporal sulcus

Abstract:

In neural systems, information processing can be facilitated by adding an optimal level of white noise. Although this phenomenon, the so-called stochastic resonance, has traditionally been linked with perception, recent evidence indicates that white noise may also exert positive effects on cognitive functions, such as learning and memory. The underlying neural mechanisms, however, remain unclear. Here, on the basis of recent theories, we tested the hypothesis that auditory white noise, when presented during the encoding of scene images, enhances subsequent recognition memory performance and modulates activity within the dopaminergic midbrain (i.e., substantia nigra/ventral tegmental area, SN/VTA). Indeed, in a behavioral experiment, we can show in healthy humans that auditory white noise-but not control sounds, such as a sinus tone-slightly improves recognition memory. In an fMRI experiment, white noise selectively enhances stimulus-driven phasic activity in the SN/VTA and auditory cortex. Moreover, it induces stronger connectivity between SN/VTA and right STS, which, in addition, exhibited a positive correlation with subsequent memory improvement by white noise. Our results suggest that the beneficial effects of auditory white noise on learning depend on dopaminergic neuromodulation and enhanced connectivity between midbrain regions and the STS-a key player in attention modulation. Moreover, they indicate that white noise could be particularly useful to facilitate learning in conditions where changes of the mesolimbic system are causally related to memory deficits including healthy and pathological aging.

https://pubmed.ncbi.nlm.nih.gov/24345178/
Forwarded from Авва
Молодой математик, выросший в Донецке и Киеве, учившийся и живший в Москве, покончил сегодня жизнь самоубийством после неудачной попытки покинуть территорию РФ. Это его прощальное письмо.

https://t.me/const_poems/101
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Forwarded from Life's Too Short
Yulia's Dream – безкоштовна науково-дослідницька програма з математики для обдарованих школярів (9-11 класів) з України🇺🇦

Програма присвячена пам’яті Юлії Здановської, 21-річної української студентки-математика, переможниці Європейської олімпіади з математики 2017 року, яка загинула від російської ракети у рідному місті Харкові.

Yulia's Dream – це ініціатива в рамках PRIMES – Програми досліджень у галузі математики, техніки та природничих наук для старшокласників Масачусетського технологічного інституту. За цією програмою учні збиратимуться онлайн раз на тиждень у невеликих групах, щоб вивчати розширені математичні теми за межами шкільної програми або працювати над математичними дослідницькими проєктами під керівництвом академічних наставників із числа аспірантів факультету математики Масачусетського технологічного інституту та спеціалістів з математики. Інструкція буде доступна українською, англійською та російською мовами.

Деталі 👉🏻math.mit.edu/research/highschool/primes/YuliasDream.php

MIT Department of Mathematics
Forwarded from Axis of Ordinary
"The Church-Turing thesis was born after Kleene got dosed with laughing gas!

Nobody knew how to use the lambda-calculus to define the "predecessor" function, which subtracts 1 from any natural number except 0, which it leaves alone. At the dentist, Kleene saw how to do it."

Source: https://twitter.com/johncarlosbaez/status/1505962963747758080
Forwarded from gerontion
Hearing is a fundamental sense of many animals, including all mammals, birds, some reptiles, amphibians, fish, and arthropods. The auditory organs of these animals are extremely diverse in anatomy after hundreds of millions of years of evolution, yet all are made up of cellular tissue and are morphologically part of the bodies of animals. Here, we show that hearing in the orb-weaving spider Larinioides sclopetarius is not constrained by the organism’s body but is extended through outsourcing hearing to its extended phenotype, the proteinaceous, self-manufactured orb web. We find that the wispy, wheel-shaped orb web acts as a hyperacute acoustic antenna to capture the sound-induced air particle movements that approach the maximum physical efficiency better than the acoustic responsivity of all previously known eardrums. By sensing the motion of web threads, the spider remotely detects and localizes the source of an incoming airborne acoustic wave, such as those emitted by approaching prey or predators. By outsourcing its acoustic sensors to its web, the spider is released from body size constraints and permits the araneid spider to increase its sound-sensitive surface area enormously, up to 10,000 times greater than the spider itself. The spider also enables the flexibility to functionally adjust and regularly regenerate its external "eardrum" according to its needs. The outsourcing and supersizing of auditory function in spiders provides unique features for studying extended and regenerative sensing and designing novel acoustic flow detectors for precise fluid dynamic measurement and manipulation.

https://www.pnas.org/doi/10.1073/pnas.2122789119
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Forwarded from Цуберок 🇺🇦 #УкрТґ
кажуть, що звичайна формула кінетичної енергії — лише наближення, яке працює при низьких швидкостях